Yonsei University · Medicine
Professor Chan Joo Lee's research lab focuses on cardiovascular epidemiology and hypertension management, with a strong emphasis on real-world outcomes, blood pressure control, and the socioeconomic impact of heart failure in aging populations. The lab investigates lifestyle interventions, pharmacological treatment strategies, and psychosocial determinants influencing hypertension control, particularly in low-risk, stage-1 hypertensive patients. Their work leverages large national health databases to inform clinical guidelines and regulatory decisions, such as the approval of Reti-CVD in Korea. The lab also explores health-related quality of life and medication adherence to improve long-term cardiovascular outcomes.
Figures are computed from collected data and may differ slightly.
The study's results underscore the growing socioeconomic burden of HF in Korea, driven by an aging population and increasing HF prevalence.
In conclusion, lifestyle modification emphasizing both diet and exercise was effective for lowering BP and should be favored over diet-only modifications.
These results led the Korean regulatory body to authorize Reti-CVD.
Evidence about the benefits of treating uncomplicated, low-risk, stage-1 hypertension is lacking. The study aimed to investigate the association between mean blood pressure (BP) and clinical outcomes, and to determine optimal BPs in treated, low-risk, stage-1 hypertension. From the National Health Insurance Service Health Examination Database, patients with stage-1 hypertension between 2005 and 2006 were selected. They had a systolic BP of 140 to 159 mm Hg or diastolic BP of 90 to 99 mm Hg. Pati
We sought to investigate the psychosocial characteristics of patients with uncontrolled hypertension and examine factors that influence blood pressure (BP) control. A total of 1011 patients with uncontrolled hypertension were enrolled in 13 tertiary hospitals. Uncontrolled hypertension was defined as systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg despite on antihypertensive therapy. Socio-demographics, anthropometrics, behavioral risk factors, medication pattern, adherence, and measures of hea
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