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Chulho Sohn

Seoul National University · Medicine

About the Lab

Professor Chulho Sohn's research lab specializes in advanced neuroimaging techniques, particularly focusing on the application of 3T MRI and perfusion imaging in acute cerebrovascular diseases. The lab investigates the diagnostic utility of sequences such as GRE T2*-weighted, FLAIR, DWI, and ASL in conditions like subarachnoid hemorrhage, brain death, and acute ischemic stroke. A key research direction involves understanding hemodynamic changes and perfusion abnormalities, especially the impact of delayed cerebral blood flow on quantitative imaging metrics like CBF in arterial occlusion. The lab also explores the pathophysiological mechanisms underlying early brain injury and stroke outcomes through multimodal MRI.

3T MRIacute strokeperfusion imagingsubarachnoid hemorrhageASL perfusion

Research Overview

Papers
415
Total Citations
8,855
Papers (5y)
92
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
92total
2021
2022
2023
2024
2025
Citations per year (5y)
826total
20212022202320242025

Selected Papers

15
1
Article|71 citations·2003
Characteristic MR imaging findings of cavernous hemangiomas in the cavernous sinus.
Chul Ho Sohn, Sang Pyo Kim, Il‐man Kim, Jeong Hyun Lee, Ho Kyu Lee
FWCI 0.4PubMedOA

Cavernous hemangiomas occur very rarely in the cavernous sinus and are difficult to diagnose preoperatively. MR images obtained in five patients with surgically verified cavernous hemangiomas in the cavernous sinus were reviewed. MR images showed hypointensity on T1-weighted images and well-defined hyperintensity on T2-weighted images with marked homogeneous enhancement after contrast material administration. We report the characteristic MR imaging observations for these lesions.

NeurologyMedicine
2
Article|41 citations·2005
MR imaging of hyperacute subarachnoid and intraventricular hemorrhage at 3T: a preliminary report of gradient echo T2*-weighted sequences.
Chul‐Ho Sohn, Seung-Kug Baik, Hee-Jung Lee, Sung-Moon Lee, Il‐man Kim, Man-Bin Yim, Jae-Suk Hwang, M. Louis Lauzon, Robert J. Sevick
FWCI 3.0PubMedOA

We describe MR imaging findings applying gradient echo (GRE) T2*-weighted and fluid-attenuated inversion recovery (FLAIR) MR images at 3T to three patients with hyperacute subarachnoid and intraventricular hemorrhage from ruptured aneurysms. Hyperacute subarachnoid and intraventricular hemorrhages (SAH and IVH) were more clearly visualized as an area of decreased signal intensity on GRE T2*-weighted sequences than on FLAIR sequences in all three patients. These preliminary results suggest that a

Radiology, Nuclear Medicine and ImagingMedicine
3
Article|36 citations·2012
Imaging Findings of Brain Death on 3-Tesla MRI
Chul‐Ho Sohn, Hwa-Pyung Lee, Jun Beom Park, Hyuk Won Chang, Ealmaan Kim, Eunhee Kim, Ui Jun Park, Hyoung-Tae Kim, Jeonghun Ku
SJR Q1FWCI 1.6Korean Journal of RadiologyOA

T2-weighted imaging, DWI, and MRA using 3T MRI may be useful for diagnosing brain death. However, SWI findings are not specific due to high false positive findings.

Public Health, Environmental and Occupational HealthMedicine
4
Article|36 citations·2018
Impact of stroke mechanism in acute basilar occlusion with reperfusion therapy
Woo‐Jin Lee, Keun‐Hwa Jung, Young Jin Ryu, Jeong‐Min Kim, Soon‐Tae Lee, Kon Chu, Manho Kim, Sang Kun Lee, Chul‐Ho Sohn, Jae‐Kyu Roh
SJR Q1FWCI 1.6Annals of Clinical and Translational NeurologyOA

Stroke mechanism has a major influence on outcomes, and outcome predictors differ according to the underlying mechanism in acute BA occlusion with EVT. Clot sign profile on pre-angiography MRI might be useful to determine the underlying mechanism.

EpidemiologyMedicine
5
Review|34 citations·2003
Contrast-enhanced MR angiography of the intracranial circulation
Chul‐Ho Sohn, Robert J. Sevick, Richard Frayne
SJR Q2FWCI 1.3Magnetic Resonance Imaging Clinics of North America
Radiology, Nuclear Medicine and ImagingMedicine
6
Article|33 citations·2013
Effect of Delayed Transit Time on Arterial Spin Labeling
Tae Jin Yun, Chul‐Ho Sohn, Moon Hee Han, Hyun‐Seung Kang, Jeong Eun Kim, Byung‐Woo Yoon, Jin Chul Paeng, Seung Hong Choi, Ji‐hoon Kim, In Chan Song, K H Chang
SJR Q1FWCI 2.1Investigative Radiology

Our results demonstrate that the correlation between the CBF values from the ASL and DSC tends to be weaker when the transit time is more delayed, with the restoration of the strength of the correlation when the TTP is extremely delayed (>25 seconds). Understanding the effect of delayed transit time on the CBF from ASL perfusion MR in a clinical setting would facilitate the proper interpretation of ASL images.

Radiology, Nuclear Medicine and ImagingMedicine
7
Article|29 citations·2014
MRI molecular imaging using GLUT1 antibody-Fe3O4 nanoparticles in the hemangioma animal model for differentiating infantile hemangioma from vascular malformation
Chul‐Ho Sohn, Seung Pyo Park, Seung Hong Choi, Sung‐Hye Park, Sukwha Kim, Lianji Xu, Sang-Hyon Kim, Jian Hur, Jaehoon Choi, Tae Hyun Choi
SJR Q1FWCI 1.5Nanomedicine Nanotechnology Biology and Medicine
SurgeryMedicine
8
Article|29 citations·2017
Detection of crossed cerebellar diaschisis in hyperacute ischemic stroke using arterial spin-labeled MR imaging
Koung Mi Kang, Chul‐Ho Sohn, Seung Hong Choi, Keun‐Hwa Jung, Roh‐Eul Yoo, Tae Jin Yun, Ji‐hoon Kim, Sun‐Won Park
SJR Q1FWCI 2.4PLoS ONEOA

ASL imaging could detect CCD in 75% of patients with hyperacute infarction. We found that CCD was more prevalent in patients with arterial occlusion, larger ischemic brain volumes, and higher initial NIHSS and mRS scores. In particular, vessel occlusion and initial mRS score appeared to be significantly related with CCD pathophysiology in the hyperacute stage.

EpidemiologyMedicine
9
Article|25 citations·2017
Evaluation of Gadolinium Retention After Serial Administrations of a Macrocyclic Gadolinium-Based Contrast Agent (Gadobutrol)
Roh‐Eul Yoo, Chul‐Ho Sohn, Koung Mi Kang, Tae Jin Yun, Seung Hong Choi, Ji Hoon Kim, Sun‐Won Park
SJR Q1FWCI 2.1Investigative Radiology

Serial administrations of gadobutrol did not result in signal increases in the DN or GP on unenhanced T1-weighted MR images due to gadolinium retention.

Materials ChemistryMaterials Science
10
Article|23 citations·2020
Association of carotid and intracranial stenosis with Alzheimer’s disease biomarkers
Koung Mi Kang, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Hye Jeong Choi, Eunjung Lee, Younghwa Lee, Jun‐Young Lee, Yu Kyeong Kim, Bo Kyung Sohn, Chul‐Ho Sohn, Dong Young Lee
SJR Q1FWCI 2.3Alzheimer s Research & TherapyOA

Neither carotid nor intracranial artery stenosis appears to be associated with brain Aβ burden, while intracranial artery stenosis is related to amyloid-independent neurodegeneration, particularly hippocampal atrophy.

Psychiatry and Mental healthMedicine
11
Article|17 citations·2009
Perfusion Computed Tomography Evaluation of Cerebral Hemodynamic Impairment in Patients With Unilateral Chronic Steno-Occlusive Disease
Eunhee Kim, Chul‐Ho Sohn, Dong Gyu Na, Jeong Eun Kim, K H Chang, Ji‐hoon Kim, Se Jeong Jeon
SJR Q3FWCI 1.2Journal of Computer Assisted Tomography

Mean transit time is the most predictive parameter for assessing decreased CVR in patients with unilateral steno-occlusive vascular disease.

Pulmonary and Respiratory MedicineMedicine
12
Article|16 citations·2020
<p>Prediction of Amyloid Positivity in Mild Cognitive Impairment Using Fully Automated Brain Segmentation Software</p>
Koung Mi Kang, Chul‐Ho Sohn, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Younghwa Lee, Jun‐Young Lee, Yu Kyeong Kim, Bo Kyung Sohn, Roh‐Eul Yoo, Tae Jin Yun, Seung Hong Choi
SJR Q2FWCI 1.2Neuropsychiatric Disease and TreatmentOA

Relative hippocampal volume measures provided by automated brain segmentation software can be useful for screening cerebral Aβ positivity in clinical practice for patients with amnestic MCI. The information may also help clinicians interpret structural MRI to predict outcomes and determine early intervention for delaying the progression to Alzheimer's disease dementia.

Psychiatry and Mental healthMedicine
13
Article|13 citations·2023
Change of iron content in brain regions after intravenous iron therapy in restless legs syndrome: quantitative susceptibility mapping study
Tae‐Joon Kim, Min Hye Kim, Jung Hwan Kim, Jin‐Sun Jun, Jung‐Ick Byun, Jun‐Sang Sunwoo, Jung-Won Shin, Sung‐Min Gho, Chul‐Ho Sohn, Ki‐Young Jung
SJR Q1FWCI 2.8SLEEPOA

Intravenous iron treatment results in changes in brain iron content which correlate to reductions in RLS severity. This suggests a connection between symptom improvement and the associated specific brain regions constituting the sensorimotor network.

EpidemiologyMedicine
14
Article|13 citations·2004
Craniopharyngioma in the Temporal Lobe: A Case Report
Chul‐Ho Sohn, Seung Kug Baik, Sang-Pyo Kim, Il‐man Kim, Robert J. Sevick
SJR Q1FWCI 0.3Korean Journal of RadiologyOA

Herein, we report on an unusual case of craniopharyngioma arising in the temporal lobe with no prior history of surgery and with no connection to the craniopharyngeal duct. MR images showed a cystic tumor with a small solid portion. To the best of our knowledge, this is the first case of a craniopharyngioma occurring in the temporal lobe.

Endocrinology, Diabetes and MetabolismMedicine
15
Article|11 citations·1992
[Doppler ultrasound study of breast tumors using color Doppler ultrasound, duplex ultrasound and the CW Doppler ultrasound].
Chul‐Ho Sohn, Werner Stolz, E.‐M. Grischke, D. Wallwiener, G. Bastert, D. von Fournier
FWCI 0.7PubMed

The preoperative examinations by doppler-sonography of 83 patients with tumors of the breast are presented. The examinations are done with newest technique: duplex-sonography in slow-flow-technique (AI 3200, Dornier); colour-sonography in MEM-technique (AI 5200, Dornier) and synchronical colour-doppler++ (Quantum 2000, Siemens) and CW-doppler-sonography (Vasocope 3, Kranzbühler). There is a markable difference between the side of carcinoma and the normal side as well as pre- and postmenopausal p

Pathology and Forensic MedicineMedicine

Research Areas

Radiology, Nuclear Medicine and ImagingPsychiatry and Mental healthGeneticsNeurologyPulmonary and Respiratory MedicineEpidemiology

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