Seoul National University · Medicine
Professor Han-Kwang Yang's research lab specializes in gastrointestinal oncology, with a primary focus on improving surgical outcomes and survival prediction in gastric cancer. The lab investigates minimally invasive surgical techniques such as laparoscopic distal gastrectomy and their impact on recovery, pain, and long-term prognosis. A key direction involves developing and validating clinical nomograms for individualized survival prediction after D2 gastrectomy, integrating data from large institutional cohorts. The lab also explores the cost-effectiveness and clinical benefits of gastric cancer screening programs, particularly in population-based settings.
Figures are computed from collected data and may differ slightly.
Laparoscopic distal gastrectomy with D2 lymphadenectomy for locally advanced gastric cancer shows benefits in terms of lower complication rate, faster recovery, and less pain compared with open surgery.
We developed a nomogram predicting 5- and 10-year overall survival after D2 gastrectomy for gastric cancer. Validation using the SNUH and CIAH data sets revealed good discrimination and calibration, suggesting good clinical utility. The nomogram improved individualized predictions of survival.
The seventh system provided a more detailed classification of prognosis than the sixth system, especially between T2 and T3 tumors and N1 and N2 tumors, although further studies were found to be needed for the N3a and N3b classification.
The screening group had significantly lower medical care expenses and showed a significantly better prognosis than the nonscreening group. On the basis of the GDP per capita, the NCSP for gastric cancer was cost-effective for treatment prognosis.
For middle-third EGC, LAPPG can be considered as a better treatment option than LADG in terms of nutritional advantage and lower incidence of gallstone.
Synchronous cancer should be considered in the preoperative workup and combined resection should be applied whenever possible. Periodic examination for metachronous cancer is necessary during the postoperative period.
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