Yonsei University · Medicine
Professor Hee Jung Kim's research lab focuses on the intersection of musculoskeletal health, sarcopenia, and chronic pain, particularly in aging populations. The lab investigates the role of muscle mass and strength in pain perception and treatment outcomes, with a strong emphasis on sarcopenia as a modifiable risk factor in degenerative spinal disease and chronic musculoskeletal pain. Research also extends to nutritional status, physical activity, and quality of life in cancer patients, highlighting the importance of systemic factors in clinical outcomes. The lab employs clinical, observational, and population-based studies to identify biomarkers and predictors for improved patient care and rehabilitation strategies.
Figures are computed from collected data and may differ slightly.
Although CYP1B1 mutations are major causes of PCG in Korea, ~70% of PCG patients have neither CYP1B1 nor MYOC mutations suggesting a high degree of genetic heterogeneity. Furthermore, the fact that 11 out of 22 patients had only one mutant allele in the CYP1B1 gene necessitates further investigation for other genetic backgrounds underlying PCG.
Aortic annular area and Valsalva sinus diameter are independent determinants for iEOA measured by preoperative CT; surgeon-dependent factors are also significant determinants in SAVR.
Monoclinic vanadium dioxide (VO₂ (M)) particles co-doped with niobium and tungsten, with potential application in smart windows, were synthesized by hydrolysis and subsequent thermal decomposition of vanadyl sulfate. All the doped VO₂ particles exhibited a monoclinic crystalline phase and the critical phase transition temperature (<i>T</i><sub>c</sub>) of VO₂ (M) was adjusted by Nb and W co-doping. The <i>T</i><sub>c</sub> of Nb-doped VO₂ (M) decreased at a rate of approximately 10 °C/at% Nb dop
High fat infiltration of the paraspinal muscles at the mid-lumbar region appeared to be an independent factor associated with poor analgesia after epidural steroid injection in elderly patients with symptomatic degenerative lumbar spinal disease receiving conservative care. However, the cross-sectional area of the paraspinal muscles was not associated with pain relief after injection.
We measured heating of isotonic saline by three fluid warmers in six experiments: saline at 5 °C or 20 °C delivered at 30, 50 or 100 ml.min(-1) . At the three flow rates, the enFLOW(®) , buddy lite(™) and ThermoSens(®) systems heated 5 °C saline to mean (SD) temperatures of: 41.1 (0.5) °C, 37.7 (0.6) °C and 39.1 (0.6) °C; to 40.3 (0.8) °C, 33.9 (1.6) °C and 39.3 (0.7) °C; and to 37.1 (0.8) °C, 24.0 (1.3) °C and 37.6 (1.0) °C, respectively, p < 0.0001 for each experiment. The mean (SD) times take
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In this study, we found that OPCAB was associated with better survival rates and renal preservation compared with on-pump CABG.
Purpose : This study aimed to investigate nutritional risk, physical activity, and quality of life (QoL) and the interaction of these factors in colorectal cancer patients.\n\nMethods : Participants were colorectal cancer patients receiving follow-up treatment at the colorectal cancer outpatient clinic of Severance Hospital in Seoul. Participants were recruited from October 25 to November 30, 2010. The survey questionnaire consisted of Nutritional Risk Score (NRS), International Physical Activit
The relationship between sarcopenia and pain remains unclear; thus, this study evaluated whether muscle strength is independently associated with neuropathic-like pain symptoms in patients with chronic musculoskeletal pain. A cut-off score of painDETECT ≥13 was used to indicate a possible neuropathic component. Handgrip strength was measured, and muscle mass was estimated. A total of 2599 patients, including 439 patients who reported neuropathic-like pain symptoms (16.9%), were included for anal
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