Kyoto University · Medicine
Professor Hiroki Shiomi's research lab specializes in interventional cardiology and structural heart disease, with a primary focus on optimizing reperfusion strategies and revascularization outcomes in acute myocardial infarction and complex coronary artery disease. The lab investigates time-sensitive interventions such as door-to-balloon and onset-to-balloon times in ST-elevation myocardial infarction (STEMI), emphasizing the clinical impact of reducing delays in treatment. Additionally, the lab conducts comparative effectiveness research on coronary revascularization strategies, particularly evaluating the long-term benefits of coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) in patients with left main coronary artery disease (ULMCAD), especially those with high anatomical complexity. Their work aims to guide evidence-based decision-making in interventional cardiology to improve patient survival and quality of life.
Figures are computed from collected data and may differ slightly.
Short onset to balloon time was associated with better 3 year clinical outcome in patients with STEMI having primary percutaneous coronary intervention, whereas the benefit of short door to balloon time was limited to patients who presented early. Efforts to minimise onset to balloon time, including reduction of patient related delay, should be recommended to improve clinical outcome in STEMI patients.
CABG as compared with PCI was associated with better long-term outcome in patients with ULMCAD, especially those with high anatomical complexity.
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