Seoul National University · Medicine
Professor Hong-Seop Kho's research lab focuses on geriatric oral health, particularly the evaluation and management of oral and maxillofacial dysfunctions in older adults. The lab investigates the impact of aging, systemic conditions, and treatment-related factors—such as radiotherapy and medication—on salivary gland function and oral mucosal integrity. Using advanced methods like natural language processing and clinical data mining, the lab aims to differentiate complex oral conditions, including temporomandibular disorders, and develop evidence-based screening tools for oral frailty and quality of life. The research emphasizes improving clinical outcomes through early detection and personalized care in geriatric populations.
Figures are computed from collected data and may differ slightly.
Xerostomia is becoming a major issue in dental and medical clinics with an increase of aged population. Medication is the most common etiology of xerostomia, while the most severe xerostomia generally occurs in patients with a history of head and neck radiotherapy. Xerostomic patients usually suffer from diminished quality of life due to various symptoms and complications. Decreased salivary output is a definite objective sign, but oral mucosal wetness is a more reliable factor for the evaluatio
Stress-related psychoendocrinological interactions throughout the menstrual cycle resulted in a decrease in oral mucosal epithelial MUC1 expression and a weakening of oral mucosal defense.
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