Yonsei University · Medicine
Professor Hyeok-Hee Lee's research lab focuses on cardiovascular and metabolic health, with a strong emphasis on the prevention and management of cardiometabolic diseases in aging populations. Her work explores the interplay between cardiovascular risk factors, diabetes, liver disease, and cancer survivorship, particularly examining how lifestyle changes, such as physical activity and smoking cessation, influence long-term cardiovascular outcomes. The lab also investigates the clinical implications of conditions like thrombocytopenia and hepatic fibrosis in patients with chronic diseases, aiming to identify early markers and improve patient prognosis.
Figures are computed from collected data and may differ slightly.
CVD mortality and hospitalization have gradually increased in the last decade, and a substantially high proportion of adults were carrying more than 1 cardiovascular risk factor in 2018. With the rapid population aging, a continued increase in CVD appears inevitable in Korea. Concerted and sustained approaches are essential to achieve early prevention and reduce the burden of CVD.
Hepatic steatosis with fibrosis is independently associated with the progression of carotid atherosclerosis in patients with type 2 diabetes.
Journal Article Smoking habit change after cancer diagnosis: effect on cardiovascular risk Get access Hyeok-Hee Lee, Hyeok-Hee Lee Department of Preventive Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of KoreaDepartment of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea https://orcid.org/0000-0002-2895-6835 Search for other works by this author on: Oxford Academic PubMed
Thrombocytopenia at CS presentation was associated with worse clinical findings, higher frequencies of complications, and longer stay at the intensive care unit. Also, thrombocytopenia was independently associated with increased 30-day mortality. (Clinical trial registration No. NCT02985008).
Journal Article Changes in physical activity and incident cardiovascular events in cancer survivors Get access Hyeok-Hee Lee, Hyeok-Hee Lee Department of Preventive Medicine, Yonsei University College of Medicine,Seoul, KoreaDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, KoreaInstitute for Innovation in Digital Healthcare, Yonsei University, Seoul, Korea https://orcid.org/0000-0002-2895-6835 Search for other works by this author on: Oxford Academic PubMed Google S
The burden of cardiometabolic risk factors among U.S. adults with hypertension has increased overall, with concurrent diabetes and hyperlipidemia now affecting more than 1 in 5. Only one-quarter of adults with hypertension, diabetes, and hyperlipidemia have all 3 conditions controlled-a proportion that has not improved in more than a decade.
Approximately half of pre-diagnosis smokers quit smoking after a cancer diagnosis. Smoking cessation was associated with a 15% reduced risk of dementia. More than 2% of pre-diagnosis non-smokers initiated or relapsed into smoking after a cancer diagnosis. Smoking initiation/relapse was associated with a 29% elevated risk of dementia.
This cohort study examines the risk of heart failure in patients by smoking status after diagnosis of cancer.
Background: The development of cancer and its treatment often entail changes in body weight. This study aimed to investigate the association of post-diagnosis body weight change with cardiovascular disease (CVD) risk in cancer survivors. Methods: From the Korean National Health Insurance database, we identified 112,565 3-year cancer survivors who had been diagnosed with cancer at age ≥20 years from 2006 through 2013 and had normal body weight (body mass index [BMI] 18.5-22.9 kg/m2) before a canc
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