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Hyun-Seung Kang

Seoul National University · Medicine

About the Lab

Professor Hyun-Seung Kang's research lab specializes in cerebrovascular disease, with a primary focus on the endovascular and surgical management of intracranial aneurysms. The lab investigates innovative interventional techniques, such as coil embolization and intra-arterial thrombolysis, to improve treatment outcomes and reduce complications like thromboembolism. Genetic factors influencing aneurysm development and recurrence are also a key research interest, particularly through the study of gene polymorphisms in extracellular matrix regulators. Advanced imaging techniques, including 3D rotational angiography, are employed to enhance diagnostic accuracy and guide long-term follow-up.

intracranial aneurysmsendovascular treatmentcoilsthromboembolismgenetic predisposition

Research Overview

Papers
323
Total Citations
5,752
Papers (5y)
69
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
69total
2021
2022
2023
2024
2025
Citations per year (5y)
352total
20212022202320242025

Selected Papers

15
1
Article|103 citations·2005
Repeat Endovascular Treatment in Post-Embolization Recurrent Intracranial Aneurysms
Hyun‐Seung Kang, Moon Hee Han, Bae Ju Kwon, O-Ki Kwon, Sung Hyun Kim
SJR Q1FWCI 3.8Neurosurgery

RE is a safe and effective treatment option in cases of recanalized or recurrent aneurysms. Close follow-up evaluation is essential in patients with intracranial aneurysms after coil embolization.

NeurologyMedicine
2
Article|93 citations·2006
Single Nucleotide Polymorphisms of Tissue Inhibitor of Metalloproteinase Genes in Familial Moyamoya Disease
Hyun‐Seung Kang, Seung‐Ki Kim, Byung-Kyu Cho, Young-Yim Kim, Yong-Seung Hwang, Kyu‐Chang Wang
SJR Q1FWCI 5.5Neurosurgery

Our findings suggest that the presence of a G/C heterozygous genotype at position -418 in TIMP2 promoter could be a genetic predisposing factor for FMMD.

RheumatologyMedicine
3
Article|73 citations·2004
Postoperative 3D angiography in intracranial aneurysms.
Hyun‐Seung Kang, Moon Hee Han, Bae Ju Kwon, Sung Il Jung, Chang Wan Oh, Dae Hee Han, Kee‐Hyun Chang
FWCI 2.2PubMedOA

3D angiography allowed us to detect more residual aneurysms after surgical clip placement than did conventional DSA, although none of those detected on only 3D angiography were judged to require additional treatment. 3D angiography may provide baseline data for the long-term follow-up of postsurgical aneurysms.

NeurologyMedicine
4
Article|71 citations·2005
Short-term outcome of intracranial aneurysms treated with polyglycolic acid/lactide copolymer-coated coils compared to historical controls treated with bare platinum coils: a single-center experience.
Hyun‐Seung Kang, Moon Hee Han, Bae Ju Kwon, O-Ki Kwon, Sung Hyun Kim, Seung Hong Choi, Kee‐Hyun Chang
FWCI 5.2PubMedOA

In this study, the incidence of recanalization was not different in aneurysms treated with PGLA-coated coils compared with historical controls treated with bare platinum coils.

NeurologyMedicine
5
Article|55 citations·2010
Is Clopidogrel Premedication Useful to Reduce Thromboembolic Events During Coil Embolization for Unruptured Intracranial Aneurysms?
Hyun‐Seung Kang, Moon Hee Han, Bae Ju Kwon, Cheolkyu Jung, Jeongeun Kim, O-Ki Kwon, Chang Wan Oh
SJR Q1FWCI 2.6Neurosurgery

Clopidogrel premedication seems to have a beneficial effect in reducing the number of procedure-related thromboembolisms during coil embolization for unruptured intracranial aneurysms, especially in female patients. Smoking and hyperlipidemia were independent risk factors related to thromboembolism.

NeurologyMedicine
6
Article|52 citations·2008
INTRA-ARTERIAL TIROFIBAN INFUSION FOR THROMBOEMBOLISM DURING ENDOVASCULAR TREATMENT OF INTRACRANIAL ANEURYSMS
Hyun‐Seung Kang, Bae Ju Kwon, Hong Gee Roh, Sung Won Yoon, Hyuk Won Chang, Jeong Eun Kim, Moon Hee Han
SJR Q1FWCI 0.8Neurosurgery

Intra-arterial tirofiban delivery appears to be a safe and effective treatment modality when thromboembolism is encountered during the endovascular treatment of intracranial aneurysms.

NeurologyMedicine
7
Article|52 citations·2005
Evaluation of the lenticulostriate arteries with rotational angiography and 3D reconstruction.
Hyun‐Seung Kang, Moon Hee Han, Bae Ju Kwon, O-Ki Kwon, Sung Hyun Kim, Kee‐Hyun Chang
FWCI 1.7PubMedOA

Analysis of LSAs with RA and 3D reconstructed images may provide useful information in patients with cerebrovascular diseases, especially before surgical and endovascular treatment.

Pulmonary and Respiratory MedicineMedicine
8
Article|50 citations·2013
Smooth-muscle progenitor cells isolated from patients with moyamoya disease: novel experimental cell model
Hyun‐Seung Kang, Youn-Joo Moon, Young-Yim Kim, Woong‐Yang Park, Ae Kyung Park, Kyu‐Chang Wang, Jeong Eun Kim, Ji Hoon Phi, Ji Yeoun Lee, Seung‐Ki Kim
SJR Q1FWCI 1.8Journal of neurosurgery

With adequate culture conditions, SPCs could be established from the peripheral blood of patients with MMD. These cells showed specific DEGs compared with healthy control volunteers. This study provides a novel experimental cell model for further research of MMD.

RheumatologyMedicine
9
Article|47 citations·2007
EMBOLIZATION OF INTRACRANIAL ANEURYSMS WITH HYDROGEL-COATED COILS
Hyun‐Seung Kang, Moon Hee Han, Tae Hong Lee, Yong Sam Shin, Hong Gee Roh, O-Ki Kwon, Bae Ju Kwon, Sun Yong Kim, Sung Hyun Kim, Hong Sik Byun
SJR Q1FWCI 5.3Neurosurgery

HydroCoil embolization seems to be a feasible treatment option in intracranial aneurysms in terms of initial aneurysmal occlusion rate and durability at the time of the follow-up evaluation; however, caution is required regarding aseptic meningitis and delayed hydrocephalus. Calculated aneurysmal volume of 600 mm3 seems to be critical in determining the anatomic outcome in aneurysms embolized with HydroCoils.

NeurologyMedicine
10
Article|45 citations·2011
Early recurrent hemorrhage after coil embolization in ruptured intracranial aneurysms
Young Dae Cho, Jong Young Lee, Jung Hwa Seo, Hyun‐Seung Kang, Jeong Eun Kim, O-Ki Kwon, Young Seob Chung, Moon Hee Han
SJR Q1FWCI 1.7Neuroradiology
NeurologyMedicine
11
Article|40 citations·2017
Antiplatelet Premedication for Stent-Assisted Coil Embolization of Intracranial Aneurysms: Low-Dose Prasugrel vs Clopidogrel
Hyun Ho Choi, Jung Jun Lee, Young Dae Cho, Moon Hee Han, Won‐Sang Cho, Jeong Eun Kim, Sang Joon An, Jong Hyeon Mun, Dong Hyun Yoo, Hyun‐Seung Kang
SJR Q1FWCI 4.1Neurosurgery

Use of low-dose PSG as an antiplatelet premedication is quick, effective, and safe for stent-assisted coil embolization of unruptured intracranial aneurysms. Prasugrel premedication significantly lowered the frequency of thromboembolic events without increasing the risk of hemorrhage.

Cardiology and Cardiovascular MedicineMedicine
12
Article|37 citations·2009
Endovascular coil embolization of anterior choroidal artery aneurysms
Hyun‐Seung Kang, Bae Ju Kwon, O-Ki Kwon, Cheolkyu Jung, Jeong Eun Kim, Chang Wan Oh, Moon Hee Han
SJR Q1FWCI 1.0Journal of neurosurgery

Coil embolization is a safe and effective treatment modality in cases of AChA aneurysms. Coil embolization enables procedural recognition of arterial compromise and immediate reestablishment of flow, thus contributing to a favorable outcome.

NeurologyMedicine
13
Article|35 citations·2013
Endovascular coil embolization of middle cerebral artery aneurysms of the proximal (M1) segment
Young Dae Cho, Woong Jae Lee, Kang Min Kim, Hyun‐Seung Kang, Jeong Eun Kim, Moon Hee Han
SJR Q1FWCI 3.7Neuroradiology
NeurologyMedicine
14
Article|32 citations·2018
Low-Dose Prasugrel vs Clopidogrel-Based Tailored Premedication for Endovascular Treatment of Cerebral Aneurysms
Won‐Sang Cho, Joongyub Lee, Eun Jin Ha, Kyung Hyun Kim, Jeongjun Lee, Young Dae Cho, Jeong Eun Kim, Moon Hee Han, Hyun‐Seung Kang
SJR Q1FWCI 2.9Neurosurgery

Abstract BACKGROUND Antiplatelet premedication is widely accepted for interventional treatment of cerebral aneurysms to prevent thromboembolism. However, antiplatelet resistance sometimes limits the effectiveness of premedication. OBJECTIVE To compare 2 groups administered low-dose prasugrel (PSG group) or clopidogrel-based tailored antiplatelet (CPG group) in terms of platelet function and procedure-related complications. METHODS A total of 411 patients with 505 unruptured aneurysms who underwe

Cardiology and Cardiovascular MedicineMedicine
15
Article|29 citations·2007
<b>Intracranial Hemorrhage After Carotid Angioplasty:</b>A Pooled Analysis
Hyun‐Seung Kang, Moon Hee Han, O-Ki Kwon, Bae Ju Kwon, Sung Hyun Kim, Chang Wan Oh
SJR Q1FWCI 2.7Journal of Endovascular Therapy

The incidence of CAS-associated ICH was significantly lower in series consisting of >100 cases. More caution should be directed toward patients with symptomatic lesions, severe stenosis, maximal ICA stenosis distal to the carotid bifurcation, and preexisting cerebral infarction.

Pulmonary and Respiratory MedicineMedicine

Research Areas

NeurologyRheumatologyPulmonary and Respiratory MedicineEpidemiologyElectrical and Electronic EngineeringSurgery

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