Seoul National University · Medicine
Professor Jae Ho Jung's research lab specializes in ophthalmic surgery and ocular pharmacology, with a focus on glaucoma-related pathophysiology, vitreoretinal surgery, and orbital disorders. The lab investigates the effects of prostaglandin analogs on orbital fat metabolism, evaluates surgical outcomes in retinal diseases such as AMD and PCV, and explores innovative techniques for correcting eyelid and orbital anatomical abnormalities. Additionally, the lab examines drug delivery mechanisms in the eye, particularly the pharmacokinetics of corticosteroids after vitreoretinal procedures.
Figures are computed from collected data and may differ slightly.
Latanoprost, travoprost, bimatoprost, and tafluprost inhibited human preadipocyte differentiation and intracellular lipid accumulation. Morphologic and metabolic changes in orbital adipocytes caused by PGF2α analogs are a possible pathophysiologic explanation of superior eyelid deepening in patients with glaucoma.
In this series, the functional outcomes of vitrectomy for vitreous hemorrhage associated with AMD were inferior to outcomes of the PCV group. Vitrectomy is beneficial for improving visual function in select cases of breakthrough vitreous hemorrhage.
This surgical technique is an effective method for the correction of coexistent epiblepharon and epicanthal fold without significant complications.
Neuro-ophthalmic manifestations and disease course of pediatric MFS were similar to those of adult MFS as stated in the literature. However, the presence of autonomic symptoms was higher and anti-GQ1b antibody positivity was lower in pediatric MFS than in adult MFS.
Intravitreal absorption and excretion of TA in the posterior subtenon space are increased after vitrectomy. Although the terminal half-life of TA was shorter, higher early concentration and similar effective duration were achieved in the vitrectomized eyes.
The intraoperative use of bevacizumab reduced inflammatory cell infiltration in the early stage of the procedure, but it was insufficient to prevent postoperative adhesion in rabbit eyes after extraocular muscle surgery.
The HRQOL of IXT children was positively related to that of their parents. A larger deviation angle and worse distance stereoacuity function may predict more-negative impacts on children and their parents, respectively.
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