Jae Il Shin
Kyung Hee University · Medicine
Jae Il Shin 교수의 연구실은 감염성 질환, 특히 코로나19와 관련된 면역 반응의 비정상적 활성화인 사이토카인 폭풍의 발병 기전을 중심으로 연구를 진행하고 있습니다. 또한 류마티스성 관절염과 같은 만성 염증성 질환에서 흡연이 유발하는 면역 및 에피제네틱 변화에 대한 기전 연구도 수행하고 있으며, 감염병과 자가면역질환의 면역학적 기전을 통합적으로 분석하고자 합니다. 정신건강 영향 평가를 포함한 패an데믹 전반의 건강 영향 분석도 연구 범위에 포함하고 있습니다.
Figures are computed from collected data and may differ slightly.
Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine storm refers to a set of clinical conditions caused by excessive immune reactions and has been recognized as a leading cause of severe COVID-19. While comparisons have been made between COVID-19 cytokine storm and other kinds of cytokine storm such as hemophagocytic lymphohistiocytosis and cytokine release syndrome, the pathogenesis
More than half of the patients without any symptoms present with CT abnormalities. Asymptomatic patients may be contagious and thus a potential source of transmission of COVID-19.
Rheumatoid arthritis (RA) is a chronic inflammatory disease caused by both genetic and environmental factors. Smoking has been implicated as one of the most important extrinsic risk factors for its development and severity. Recent developments have shed light on the pathophysiology of RA in smokers, including oxidative stress, inflammation, autoantibody formation and epigenetic changes. The association of smoking and the development of RA have been demonstrated through epidemiologic studies, as
Abstract The COVID‐19 pandemic and related restrictions can impact mental health. To quantify the mental health burden of COVID‐19 pandemic, we conducted a systematic review and meta‐analysis, searching World Health Organization COVID‐19/PsycInfo/PubMed databases (09/29/2020), including observational studies reporting on mental health outcomes in any population affected by COVID‐19. Primary outcomes were the prevalence of anxiety, depression, stress, sleep problems, posttraumatic symptoms. Sensi
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