Yonsei University · Medicine
Professor Jee Suk Chang's research lab specializes in radiation oncology and medical physics, with a strong focus on improving the precision and safety of radiation therapy. The lab investigates advanced image-guided treatment techniques, including atlas-based segmentation and auto-contouring for head and neck structures, to enhance treatment planning efficiency. It also explores patient-specific anatomical changes—such as bladder volume variations in rectal cancer patients—aimed at optimizing treatment outcomes through personalized interventions. Additionally, the lab contributes to the clinical application and evaluation of intensity-modulated radiation therapy (IMRT) in breast cancer, emphasizing treatment planning optimization and quality assurance.
Figures are computed from collected data and may differ slightly.
Until recently, chemotherapy with a combination of anthracycline and cytosine arabinoside was the most effective treatment for acute promyelocytic leukaemia (APL) ( Fenaux & Degos, 1996). This can be safely combined with anti-fibrinolytic drugs such as tranexamic acid for the attempted prophylaxis of haemorrhage without the occurrence of thrombolytic complications. However, several studies have now demonstrated that all-trans retinoic acid (ATRA) can induce complete remission of APL with progres
<b>Background:</b> While atlas segmentation (AS) has proven to be a time-saving and promising method for radiation therapy contouring, optimal methods for its use have not been well-established. Therefore, we investigated the relationship between the size of the atlas patient population and the atlas segmentation auto contouring (AC) performance. <b>Methods:</b> A total of 110 patients' head planning CT images were selected. The mandible and thyroid were selected for this study. The mandibles an
To our knowledge, this study is the first to prove that there are bladder volume variations and a reduction in bladder volume in rectal cancer patients. Moreover, our results will serve as the basis for implementation of bladder training to patients receiving RT with full bladder.
Radiation therapy (RT) plays a critical role in breast cancer treatment. In the modern technological era, innovations and progress in breast RT and delivery techniques have greatly improved the clinical outcomes. Intensity-modulated RT (IMRT) is a modern RT technology that permits the modulation of RT beams, ensuring a more uniform dose distribution through the target tissue and better avoidance of underlying critical structures. Recently, several studies have been published on breast IMRT. Howe
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