The University of Tokyo · Health Professions
Professor Kayo Waki's research lab specializes in digital health interventions for chronic disease management, particularly diabetes care. The lab focuses on developing and evaluating remote patient monitoring systems that integrate real-time data transmission, personalized feedback, and dietary support to improve glycemic control and patient engagement. Key research directions include the usability and feasibility of IT-based health systems, such as DialBetics and SMART-D, with an emphasis on patient-centered design and clinical outcomes. The lab also investigates lifestyle factors, including diet and alcohol consumption, in relation to diabetes risk in Japanese populations.
Figures are computed from collected data and may differ slightly.
Numerous diabetes-management systems and programs for improving glycemic control to meet guideline targets have been proposed, using IT technology. But all of them allow only limited-or no-real-time interaction between patients and the system in terms of system response to patient input; few studies have effectively assessed the systems' usability and feasibility to determine how well patients understand and can adopt the technology involved. DialBetics is composed of 4 modules: (1) data transmi
Established risk factors for diabetes in western populations were also identified as predictors of the disease among Japanese. Moderate to high alcohol consumption was positively associated with the incidence of diabetes in Japanese lean (BMI < or = 22 kg/m2) men.
Our findings may provide information to help clinicians make timely interventions to avoid MAs.
1. This is a retrospective study using the UNOS database to examine the effects of various recipient, donor and transplant factors on 10-year liver graft survivals. A total of 68,776 adult liver transplants were reported to OPTN/UNOS from September 1987 to July 2006. Recipient, donor and transplant characteristics were compared using the paired t test for continuous variables. The chi-square tests were used to compare categorical variables. We calculated actual liver graft survival rates using t
DialBetics with FoodLog was shown to be an effective and convenient tool, its new meal-photo input function helping provide patients with real-time support for diet modification.
Using SMART-D was feasible, and the system was well regarded by patients. Further study with larger scale cohorts and longer study and follow-up periods is needed to evaluate the effects of SMART-D on clinical outcomes and quality of life.
Approximately half of the patients showed interest in using an ICT-based self-management tool. Willing patients may expect ICT-based self-management tools to complement outpatient visits and to make self-management easier. Starting with patients who display the willingness factors might optimize programs based on such tools.
Simultaneous pancreas-kidney transplantation (SPK) is considered the treatment of choice for type 1 diabetic patients with end-stage renal disease. The American Diabetes Association supports pancreas transplantation for diabetic patients who have had, or plan to have, a kidney transplant (1). When the procedure is successful, a majority of pancreas transplant recipients have normal levels of glycemia and normal to nearly normal levels of HbA1c (2,3), improving their quality of life (3,4). Howeve
Long-term pancreas graft survival has remained unchanged despite the dramatic decreases in technical failures and early acute rejection rates that have contributed to prolonged SPK graft survival.
A personalized smartphone-based mHealth intervention based on SCT is feasible and effective at promoting physical activity among type 2 diabetes patients. The methodology of the intervention could be readily applied to other patient populations.
Background The role of anti–human leukocyte antigen (HLA) antibodies in operational tolerance (OT) after pediatric living-donor liver transplantation (LDLT) remains inconclusive. We investigated whether the presence of HLA antibodies impeded the development of OT. Methods We retrospectively examined the prevalence of anti-HLA antibodies in pediatric LDLT recipients before transplantation and at 3 weeks after transplantation and analyzed the significance of those antibodies in relation to later O
Self-management is a key component of diabetes therapy.1 We developed a real-time partially automated interactive system—DialBetics—to achieve diabetes self-management. This is the first system combining information technology and natural language processing (NLP) that performs real-time automated text communication with patients, increasing their convenience while minimizing health care providers’ workload and cost.2 A pilot study was conducted to assess the safety, usability, and impact of rem
It is apparent from calculations that for paired kidney donation programs, a national program will provide optimum benefit. To obviate major problems associated with donors traveling long distances, we propose shipping donor kidneys. Evidence is provided from the United Network for Organ Sharing (UNOS) Kidney Transplant Registry, that 14,873 immediate functioning kidneys from deceased head-trauma donors with an average cold ischemia time of 18.3 h had 85.7% three-yr graft survival compared with
Based upon data reported to the OPTN/ UNOS Pancreas Transplant Registry from October 1987- November 2007, overall deceased donor pancreas graft survival rates at 10 years improved from 43% for transplants prior to 1990 to 48% for transplants between 1995-1999. Overall graft survival rates have not improved substantially since 2000. The major causes of pancreas graft failure were technical (40%) and acute rejection (15%) during the early posttransplant period, and chronic rejection (25%) of graft
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