Yonsei University · Engineering
Professor Kyungho Yoon's research lab specializes in computational biomedical engineering, focusing on the development of advanced simulation and modeling techniques for non-invasive brain stimulation and thermal ablation therapies. The lab integrates physics-based modeling, machine learning, and medical imaging to enable real-time, patient-specific prediction of acoustic and thermal fields in biological tissues. Key research directions include transcranial focused ultrasound (tFUS) for neuromodulation, super-resolution simulation for improved treatment guidance, and personalized radiofrequency ablation using physics-informed neural networks. The lab emphasizes clinical translation by addressing computational efficiency and accuracy in complex biological environments such as the human skull and skin.
Figures are computed from collected data and may differ slightly.
Remarkable improvement of the ionic conductivity of inorganic solid electrolytes (SEs) exceeding 10 mS cm<sup>-1</sup> at room temperature has opened up the opportunities to realize the commercialization of solid-state batteries (SSBs). The transition to the intrinsically inflammable SEs also promises that SSBs would successfully utilize lithium metal anode thus achieving the high-energy-density lithium metal batteries without the risk of a safety hazard. However, the practical operation of soli
Low-intensity focused ultrasound (FUS) has significant potential as a non-invasive brain stimulation modality and novel technique for functional brain mapping, particularly with its advantage of greater spatial selectivity and depth penetration compared to existing non-invasive brain stimulation techniques. As previous studies, primarily carried out in small animals, have demonstrated that sonication parameters affect the stimulation efficiency, further investigation in large animals is necessar
All-solid-state batteries are considered as one of the attractive alternatives to conventional lithium-ion batteries, due to their intrinsic safe properties benefiting from the use of non-flammable solid electrolytes in ASSBs. However, one of the issues in employing the solid-state electrolyte is the sluggish ion transport kinetics arising from the chemical and physical instability of the interfaces among solid components including electrode material, electrolyte and additive agents. In this wor
Transcranial focused ultrasound (tFUS) is emerging as a non-invasive brain stimulation modality. Complicated interactions between acoustic pressure waves and osseous tissue introduce many challenges in the accurate targeting of an acoustic focus through the cranium. Image-guidance accompanied by a numerical simulation is desired to predict the intracranial acoustic propagation through the skull; however, such simulations typically demand heavy computation, which warrants an expedited processing
In this paper, we propose a continuum mechanics based 3-D beam finite element with cross-sectional discretization allowing for warping displacements. The beam element is directly derived from the assemblage of 3-D solid elements, and this approach results in inherently advanced modeling capabilities of the beam element. In the beam formulation, warping is fully coupled with bending, shearing, and stretching. Consequently, the proposed beam elements can consider free and constrained warping condi
The all-solid-state battery (ASSB) has become one of the most promising next-generation battery systems, since the aspect of safety has emerged as a crucial criterion for new large-scale applications such as in electric vehicles. Despite the recent remarkable progress in the performance enhancement, the real-world implementation of the ASSB still requires full comprehension/evaluation of its properties and performance under various practical operational conditions. Unlike batteries employed in c
It was concluded that higher bone level has a biomechanical advantage with respect to stress concentration.
In this research, we developed multivariable-incorporating SR neural networks for transcranial focused ultrasound simulation. Our super-resolution technique may contribute to promoting the safety and efficacy of tFUS-mediated NIBS by providing on-site feedback information on the intracranial pressure field to the operator.
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