Tohoku University · Agricultural and Biological Sciences
Professor Minoru Ueda's research lab specializes in regenerative medicine and biomaterials, focusing on the development of bioactive scaffolds for tissue engineering. The lab investigates the osteogenic potential of calcium phosphate-based materials, such as beta-tricalcium phosphate (beta-TCP) and hydroxyapatite (HA), in combination with mesenchymal stem cells (MSCs) for bone regeneration. Key research directions include optimizing scaffold design for enhanced cell differentiation and bone formation, as well as evaluating in vivo performance through histological and biochemical analyses. The lab aims to translate these findings into clinical applications for bone repair and regeneration.
Figures are computed from collected data and may differ slightly.
Bone marrow has been shown to contain a population of rare cells capable of differentiating to the cells that form various tissues. These cells, referred to as mesenchymal stem cells (MSCs), are capable of forming bone when implanted ectopically in an appropriate scaffold. The aim of this study was to investigate the potential of a new beta-tricalcium phosphate (beta-TCP) as a scaffold and to compare the osteogenic potential between beta-TCP and hydroxyapatite (HA). The beta-TCP and HA loaded wi
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