Sungkyunkwan University · Medicine
Professor Sang Won Seo's research lab specializes in the intersection of neuroscience, cognitive aging, and neurodegenerative diseases, with a focus on understanding the neural and biological mechanisms underlying cognitive decline in conditions such as Alzheimer’s disease and frontotemporal dementia. The lab investigates the impact of metabolic and vascular risk factors—like NAFLD—on brain health and cognition, while also exploring neuroimaging and pathological markers to predict disease progression. Additionally, the lab contributes to fundamental physics through studies on quantum phenomena in ultracold atomic systems, particularly vortex dynamics and spin textures in Bose-Einstein condensates.
Figures are computed from collected data and may differ slightly.
NAFLD was independently associated with lower cognitive performance independent of CVD and its risk factors. Given the scarcity of risk factors associated with age-related cognitive decline, these findings may have significant implications.
Our findings suggest the presence of hierarchy between svMCI and SVaD, and that the cognitive decline from svMCI to SVaD is associated with lesions in dorsolateral prefrontal and temporal cortices.
We report on the observation of half-quantum vortices (HQVs) in the easy-plane polar phase of an antiferromagnetic spinor Bose-Einstein condensate. Using in situ magnetization-sensitive imaging, we observe that pairs of HQVs with opposite core magnetization are generated when singly charged quantum vortices are injected into the condensate. The dynamics of HQV pair formation is characterized by measuring the temporal evolutions of the pair separation distance and the core magnetization, which re
In a two-dimensional (2D) classical fluid, a large-scale flow structure emerges out of turbulence, which is known as the inverse energy cascade where energy flows from small to large length scales. An interesting question is whether this phenomenon can occur in a superfluid, which is inviscid and irrotational by nature. Atomic Bose-Einstein condensates (BECs) of highly oblate geometry provide an experimental venue for studying 2D superfluid turbulence, but their full investigation has been hinde
Patients with FTD and FTLD often develop symptoms after age 65, and age at onset represents an important consideration when making antemortem neuropathologic predictions.
Our findings suggest that the protective effects of education against cognitive decline remain in early-stage aMCI and disappear in late-stage aMCI.
We present an experimental study on the interaction and dynamics of half-quantum vortices (HQVs) in an antiferromagnetic spinor Bose-Einstein condensate. By exploiting the orbit motion of a vortex dipole in a trapped condensate, we perform a collision experiment of two HQV pairs, and observe that the scattering motions of the HQVs is consistent with the short-range vortex interaction that arises from nonsingular magnetized vortex cores. We also investigate the relaxation dynamics of turbulent co
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