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Sehun Jang

Seoul National University · Biochemistry, Genetics and Molecular Biology

About the Lab

Professor Sehun Jang's research lab focuses on pediatric immunology and environmental health, with a strong emphasis on food allergies, atopic dermatitis, and the impact of environmental exposures on child health. The lab investigates the pathophysiology of allergic diseases, including the role of immune pathways such as NLRP3 inflammasome in allergic rhinitis, and explores clinical interventions like oral immunotherapy and baked food diets to induce tolerance in young children. A key focus is on understanding the systemic and long-term effects of allergic and inflammatory conditions, as well as the neurotoxic potential of low-level environmental pollutants like toluene on fetal and child development. The lab integrates clinical research with molecular mechanisms to improve quality of life and health outcomes in pediatric populations.

food allergyatopic dermatitisenvironmental exposureimmunotherapypediatric immunology

Research Overview

Papers
2
Total Citations
2
Papers (5y)
2
Primary Field
Biochemistry, Genetics and Molecular Biology

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
2total
2024
2025
Citations per year (5y)
2total
20242025

Selected Papers

2
1
Article|2 citations·2024
NLRP3 inhibition attenuates the allergic rhinitis symptoms in a mouse model
Minhyung Lee, Youngkyung Ko, Sehun Jang, Chan Hee Gil, Kyoung Mi Eun, Yulian Zhang, Sung‐Woo Cho, Dae Woo Kim, Hyun Jik Kim, Chae‐Seo Rhee
SJR Q3FWCI 0.5Asian Pacific Journal of Allergy and ImmunologyOA

NLRP3 inflammasome signaling pathway may be an alternative pathway to induce AR symptoms in OVA-induced AR model. MCC950 is a specific inhibitor of NLRP3 cascade, which attenuates AR symptoms regardless of IgE.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
Article|0 citations·2025
Effects of dupilumab on skin symptoms and food allergen sensitization in infants and young children with moderate to severe atopic dermatitis
Jeongmin Song, Sehun Jang, Sanghee Shin, Sukyung Kim, Kangmo Ahn, Jihyun Kim
Allergy Asthma & Respiratory DiseaseOA
DermatologyMedicine

Research Areas

Molecular BiologyDermatology

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