Sehun Jang
Seoul National University · Biochemistry, Genetics and Molecular Biology
About the Lab
Professor Sehun Jang's research lab focuses on pediatric immunology and environmental health, with a strong emphasis on food allergies, atopic dermatitis, and the impact of environmental exposures on child health. The lab investigates the pathophysiology of allergic diseases, including the role of immune pathways such as NLRP3 inflammasome in allergic rhinitis, and explores clinical interventions like oral immunotherapy and baked food diets to induce tolerance in young children. A key focus is on understanding the systemic and long-term effects of allergic and inflammatory conditions, as well as the neurotoxic potential of low-level environmental pollutants like toluene on fetal and child development. The lab integrates clinical research with molecular mechanisms to improve quality of life and health outcomes in pediatric populations.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
2NLRP3 inflammasome signaling pathway may be an alternative pathway to induce AR symptoms in OVA-induced AR model. MCC950 is a specific inhibitor of NLRP3 cascade, which attenuates AR symptoms regardless of IgE.
Research Areas
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