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Sung Hyun Lee

Seoul National University · Medicine

About the Lab

Professor Sung Hyun Lee's research lab specializes in clinical and translational research with a focus on improving patient outcomes through advanced anesthetic techniques, musculoskeletal surgery, and predictive modeling in chronic pain. The lab investigates innovative approaches such as ultrasound-guided nerve blocks and arthroscopic repair techniques to enhance postoperative recovery and reduce complications. Additionally, it applies machine learning to predict chronic lower back pain, aiming to enable early intervention and personalized treatment strategies. The integration of precise clinical interventions with data-driven methodologies defines the lab’s interdisciplinary research direction.

acute pain managementmachine learning in healthcarearthroscopic surgeryultrasound-guided interventionschronic pain prediction

Research Overview

Papers
263
Total Citations
2,881
Papers (5y)
78
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
78total
2022
2023
2024
2025
2026
Citations per year (5y)
234total
20222023202420252026

Selected Papers

15
1
Article|111 citations·2003
Empirical model of the acoustic impedance of a circular orifice in grazing mean flow
Seong-Hyun Lee, Jeong–Guon Ih
SJR Q1FWCI 1.3The Journal of the Acoustical Society of America

Although there are many analytical and empirical models for orifice impedance, the predicted acoustical performance when adopting any one of them sometimes shows a large discrepancy with the measured result in some cases. In order to obtain a new practical and precise empirical impedance model under grazing flow conditions, the acoustic impedance of circular orifices has been measured with a variation of the involved parameters under very carefully tested and controlled measurement conditions. T

Mechanics of MaterialsEngineering
2
Article|95 citations·2020
Application of machine learning approaches for osteoporosis risk prediction in postmenopausal women
Jae‐Geum Shim, Dong Woo Kim, Kyoung‐Ho Ryu, Eun-Ah Cho, Jin Hee Ahn, Jeong-In Kim, Sung Hyun Lee
SJR Q1FWCI 8.2Archives of Osteoporosis
Orthopedics and Sports MedicineMedicine
3
Article|83 citations·2009
Hepatic veno-occlusive disease in children after hematopoietic stem cell transplantation: incidence, risk factors, and outcome
Sung Hyun Lee, Kwai Han Yoo, Ki Woong Sung, Hong Hoe Koo, Younghoon Kwon, Minji Kwon, H J Park, B-K Park, Yoonju Kim, Jongmoo Park, H J Im, Juwon Seo
SJR Q1FWCI 2.5Bone Marrow Transplantation
GeneticsMedicine
4
Article|63 citations·2020
Evaluation of ultrasound-guided erector spinae plane block for postoperative management of video-assisted thoracoscopic surgery: a prospective, randomized, controlled clinical trial
Jae‐Geum Shim, Kyoung‐Ho Ryu, Pyoung On Kim, Eun-Ah Cho, Jin Hee Ahn, Ji-Eun Yeon, Sung Hyun Lee, Du–Young Kang
SJR Q2FWCI 8.4Journal of Thoracic DiseaseOA

A single preoperative injection of ESPB with ropivacaine may improve acute postoperative analgesia and emergence agitation in patients undergoing VATS.

SurgeryMedicine
5
Article|49 citations·2007
A model of acoustic impedance of perforated plates with bias flow considering the interaction effect
Seong-Hyun Lee, Jeong–Guon Ih, K.S. Peat
SJR Q1FWCI 1.6Journal of Sound and Vibration
Biomedical EngineeringEngineering
6
Article|48 citations·2017
Wastewater treatment and electricity generation from a sunlight-powered single chamber microbial fuel cell
Sung Hyun Lee, Kyeong-Seok Lee, Saurav Sorcar, Abdul Razzaq, Craig A. Grimes, Su‐Il In
SJR Q2FWCI 2.8Journal of Photochemistry and Photobiology A Chemistry
Environmental EngineeringEnvironmental Science
7
Article|35 citations·2008
Antioxidant and Hepatoprotective Activities of <i>Cirsium setidens</i> NAKAI against <font>CCl</font><sub>4</sub>-Induced Liver Damage
Sung Hyun Lee, Seong-Il Heo, Lan Li, Min Jie Lee, Myeong‐Hyeon Wang
SJR Q1FWCI 0.5The American Journal of Chinese Medicine

The antioxidant activity and hepatoprotective potential of Cirsium setidens Nakai, a widely used medicinal plant, were investigated. The n-butanol (n-BuOH) fraction of leaves and roots of C. setidens had a higher 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity than the other soluble fractions. The n-BuOH fraction of roots of C. setidens had a significant hepatoprotective activity at a dose of 500 mg/kg compared to that of a standard agent. The biochemical results were confirmed

Pulmonary and Respiratory MedicineMedicine
8
Article|35 citations·2021
Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years
Jae‐Geum Shim, Kyoung‐Ho Ryu, Eun-Ah Cho, Jin Hee Ahn, Hong Kyoon Kim, Yoon-Ju Lee, Sung Hyun Lee
SJR Q2FWCI 3.9MedicinaOA

<i>Background and Objectives</i>: Chronic lower back pain (LBP) is a common clinical disorder. The early identification of patients who will develop chronic LBP would help develop preventive measures and treatment. We aimed to develop machine learning models that can accurately predict the risk of chronic LBP. <i>Materials and Methods</i>: Data from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014 and 2015 (KNHANES VI-2, 3) were screened for selecting patients w

PharmacologyMedicine
9
Article|33 citations·2018
Ultrasound-Guided Prolotherapy with Polydeoxyribonucleotide for Painful Rotator Cuff Tendinopathy
Kyoung Ho Ryu, Dongchan Ko, Goeun Lim, Eugene S. Kim, Sung Hyun Lee
SJR Q1FWCI 2.8Pain Research and ManagementOA

PDRN prolotherapy may improve the conservative treatment of painful rotator cuff tendinopathy for a specific subset of patients.

SurgeryMedicine
10
Article|21 citations·2020
Estimating the biological effects of helium, carbon, oxygen, and neon ion beams using 3D silicon microdosimeters
Sung Hyun Lee, Kota Mizushima, Ryosuke Kohno, Y. Iwata, Shunsuke Yonai, Toshiyuki Shirai, Vladimir Pan, David Bolst, Linh T. Tran, Anatoly Rosenfeld, Masao Suzuki, Taku Inaniwa
SJR Q1FWCI 1.0Physics in Medicine and Biology

In this study, the survival fraction (SF) and relative biological effectiveness (RBE) of pancreatic cancer cells exposed to spread-out Bragg peak helium, carbon, oxygen, and neon ion beams are estimated from the measured microdosimetric spectra using a microdosimeter and the application of the microdosimetric kinetic (MK) model. To measure the microdosimetric spectra, a 3D mushroom silicon-on-insulator microdosimeter connected to low noise readout electronics (MicroPlus probe) was used. The para

Pulmonary and Respiratory MedicineMedicine
11
Article|19 citations·2007
Effect of non-uniform perforation in the long concentric resonator on transmission loss and back pressure
Seong-Hyun Lee, Jeong–Guon Ih
SJR Q1Journal of Sound and Vibration
Biomedical EngineeringEngineering
12
Article|19 citations·2004
Polycrystalline sputtered Cd(Zn, Mn)Te films for top cells in PV tandem structures
Sung Hyun Lee, Akhlesh Gupta, A. Compaan
FWCI 2.7Physica status solidi. C, Conferences and critical reviews/Physica status solidi. C, Current topics in solid state physics

The CdTe-ZnTe or CdTe–MnTe alloy system is evaluated for application in high efficiency polycrystalline thin film multijunction solar cells. CdZnTe alloy films with 1.6 and 1.7 eV band gap and CdMnTe with 1.6 and 1.8 eV were deposited by RF magnetron sputtering from targets made of mixed powders of CdTe and ZnTe (25% and 40%) or MnTe (13% and 25%), respectively. Without postdeposition treatment, however, both of these alloy films exhibit quite low photovoltaic performance when used to make cells

Electrical and Electronic EngineeringEngineering
13
Article|18 citations·2022
Machine learning for prediction of postoperative nausea and vomiting in patients with intravenous patient-controlled analgesia
Jae‐Geum Shim, Kyoung‐Ho Ryu, Eun-Ah Cho, Jin Hee Ahn, Yun Byeong, Goeun Lim, Sung Hyun Lee
SJR Q1FWCI 3.7PLoS ONEOA

We developed and validated machine learning models for predicting PONV in the first 24 h. The machine learning model showed better performance than the Apfel model in predicting PONV.

SurgeryMedicine
14
Article|18 citations·1989
The effects of gamma irradiation on the survival and development of Clonorchis sinensis metacercariae
Sung Hyun Lee, Yeoung‐Hyun Park, W M Sohn, Sung‐Tae Hong, J Y Chai
Korean Journal of ParasitologyOA

The effects of gamma irradiation on the survival and development of C. sinensis metacercariae were studied to evaluate the feasibility of irradiation as a control measure for clonorchiasis. Pseudorasbora parva were collected at an endemic river of clonorchiasis and were used for irradiation of the fluke in three schemes. The first (Scheme 1) was irradiation of the isolated metacercariae from the fish followed by infection to experimental rats. The second (Scheme 2) was irradiation of the fish, a

EcologyEnvironmental Science
15
Article|15 citations·2020
Anti-Allodynic Effects of Polydeoxyribonucleotide in an Animal Model of Neuropathic Pain and Complex Regional Pain Syndrome
Sung Hyun Lee, Sie Hyeon Yoo, Hae-Jin Lee, Donggyu Han, Ji-Young Lee, Seung Hwan Jeon, Eun-Ah Cho, Hue Jung Park
SJR Q2FWCI 1.1Journal of Korean Medical ScienceOA

SC administration of PDRN results in the attenuation of allodynia and activation of astrocytes in neuropathic pain or CRPS models. We propose that PDRN can have significant potential advantages in neuropathic pain treatment.

PhysiologyMedicine

Research Areas

Pulmonary and Respiratory MedicineBiomedical EngineeringSurgeryEpidemiologyElectrical and Electronic EngineeringAutomotive Engineering

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