Sungkyunkwan University · Medicine
Professor Sung-Ji Park's research lab specializes in cardiovascular imaging and risk stratification, with a focus on echocardiography, cardiac magnetic resonance (CMR), and biomarkers in predicting perioperative and long-term cardiovascular outcomes. The lab investigates subclinical cardiac changes in aortic stenosis and hypertension, particularly using advanced imaging techniques to detect early structural and functional deterioration. Key research directions include identifying clinical predictors of postpartum chronic hypertension in women with hypertensive disorders of pregnancy and evaluating the prognostic value of parameters such as E/e' ratio in atrial fibrillation. The lab aims to refine risk assessment tools and guide personalized management in both noncardiac surgical and maternal cardiovascular settings.
Figures are computed from collected data and may differ slightly.
TTE was modestly predictive of perioperative cardiovascular events but was not superior to NT-proBNP. Moreover, it did not have incremental value to the clinically determined risk. The results of our study did not support the use of routine echocardiography before noncardiac surgery.
URL: https://www.clinicaltrials.gov; Unique identifier: NCT04231331.
Although CR is best related to baseline resting LVESDI, one-third of patients were found to have discordance between the presence of CR and the LV dimension recommended for aortic valve replacement (AVR) in minimally symptomatic patients with severe AR, suggesting that exercise test may be able to further stratify the current guideline for AVR.
These findings demonstrate the usefulness of CMR for early detection of subclinical LV structural and functional deterioration in AS patients.
E/e' ratio is a useful independent prognostic parameter for predicting mortality in patients with AF with preserved LV systolic function.
Background and Objectives: The role of preoperative transthoracic echocardiography (TTE) for the risk stratification has not been well investigated yet. We compared the predictive power of TTE with N-terminal pro-brain natriuretic peptide (NT-proBNP), a representative biomarker that predicts perioperative cardiovascular risk, and investigated whether these tests have incremental value to the clinically determined risk. Subjects and Methods: We evaluated the Revised Cardiac Risk Index (RCRI), TTE
To recognize MH, it is practical to investigate those patients who are taking multiple antihypertensive drugs and have a high OBP with a high FBG level. The term "ME" identifies MH more appropriately than the term "negative white-coat effect".
The concentration of betaARK1 in lymphocytes is greater in hypertensive individuals with LVH than in those without LVH and parallels the degree of hypertrophy. Generalized alterations in beta-adrenergic signalling, including betaARK1, could be a major contributory factor in the development of LVH in hypertension, and the concentration of betaARK1 in lymphocytes can reflect the development of LVH in a patient with hypertension.
RT3DE and 2D MSTE can be used to identify subtle contractile dysfunction triggered by increased LV wall thickness in severe AS with normal LVEF. Therefore, RT3D STE and 2D MSTE may provide additional information that can facilitate decision-making regarding severe AS patients with increased LV wall thickness and normal LV function.
Aortic stenosis is the most common type of valvular heart disease. Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular remodeling response that ensues. In aortic stenosis, therapeutic decision essentially depends on symptomatic status, stenosis severity, and status of left ventricular systolic function. Imaging is fundamental for the initial diagnostic work-up, follow-up, and selection of the optimal timing and type of intervention. Noninvasive imaging h
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