Tohoku University · Medicine
Professor Tetsuya Kodama's research lab specializes in biomedical engineering and sustainable energy technologies, with a focus on therapeutic angiogenesis, targeted drug delivery using ultrasound and microbubbles, and solar-driven thermochemical processes for hydrogen and syngas production. The lab develops innovative animal models for lymph node metastasis and applies advanced imaging techniques to study cancer progression and drug delivery. It also pioneers solar reactor systems using fluidized bed technology for clean fuel production.
Figures are computed from collected data and may differ slightly.
The detailed arterial anatomy of murine hindlimb and collateral routes deduced from the anatomy are described. Limitations on designs of ischemia models in view of anatomical variations are proposed. These observations will contribute to the development of animal studies of therapeutic angiogenesis using murine hindlimb ischemia models.
Cell permeabilization using microbubbles (MB) and low-intensity ultrasound (US) have the potential for delivering molecules into the cytoplasm. The collapsing MB and cavitation bubbles created by this collapse generate impulsive pressures that cause transient membrane permeability, allowing exogenous molecules to enter the cells. To evaluate this methodology in vitro and in vivo, we investigated the effects of low-intensity 1-MHz pulsed US and MB combined with cis-diamminedichloroplatinum (II) (
Solar CO2 gasification of coal was demonstrated under direct irradiation of the fluidized coal bed with the concentrated visible light from a solar furnace simulator in a small-scale quartz reactor. Pulverized Australian bituminous coal (the average particle size of 140 μm) was tested. The peak energy-flux density, FDpeak of the incident light beam was varied up to 1270 kW m-2. The light-to-chemical (enthalpy) energy conversion via the solar gasification increased with increasing the energy-flux
A two-step thermochemical water splitting cycle using nonstoichiometric cerium oxide is a promising solar thermochemical hydrogen production process. One of the present authors has developed new solar reactors using “internally circulating fluidized beds” with cerium oxide particles for the high-temperature cycle. These solar reactors need to be combined with a beam-down solar concentrating system. Niigata University, University of Miyazaki, and Mitaka Kohki Co. Ltd. recently started an R&D join
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