Yonsei University · Dentistry
Professor Ui-Won Jung's research lab specializes in oral and maxillofacial regenerative medicine, focusing on tissue engineering, biomaterials, and advanced drug delivery systems for dental and craniofacial applications. Key research directions include the development of dissolving microneedles for local anesthetic delivery, bioactive coatings for dental implants, and growth factor-mediated bone regeneration using synthetic bone graft substitutes. The lab integrates clinical dentistry with materials science and translational research to improve outcomes in implant therapy and soft tissue management.
Figures are computed from collected data and may differ slightly.
The palatal masticatory mucosa thickness increased from the canine to premolar region but decreased at the first molar region and increased again in the second molar region, with the thinnest area at the first molar region and the thickest at the second premolar region. The canine to premolar region seems to be the most appropriate donor site that contains a uniformly thick mucosa. CT can be considered an alternative method for the measurement of palatal soft tissue thickness.
Lidocaine is a local anesthetic agent used in the form of injection and topical cream. However, these formulation types have limitations of being either painful or slow-acting, thereby hindering effective and complete clinical performance of lidocaine. Dissolving microneedles (DMNs) are used to overcome these limitations owing to their fast onset time and minimally invasive administration methods. Using hyaluronic acid and lidocaine to produce the drug solution, a lidocaine HCl encapsulated DMN
These HA-coated implants exhibited increased roughness, crystallinity, and wettability when compared with RBM implants.
rhBMP-4 combined with either small- or large-particle beta-TCP had a significant effect on the induction of bone formation compared to either a small- or large-particle beta-TCP control or a sham-surgery control. Within the parameters of this study, varying the particle size of beta-TCP did not seem to have a significant effect on bone formation.
It can be concluded that the addition of BMP-2 to CBCP resulted in a greater initial augmented volume as a result of postoperative swelling, which is replaced by early bone formation, and it was prominent near the Schneiderian membrane.
Within the limitations of this retrospective study, it was concluded that implant therapy can be successfully provided to elderly patients and that age alone does not seem to affect the implant survival rate.
The long-term evaluation of root coverage with a gingival cuff of the maxillary tuberosity area showed it to be an easier method than obtaining the graft from palatal masticatory mucosa, with a highly predictable prognosis.
The purpose of this study was to evaluate the effects of a chitosan membrane coated with polylactic and polyglycolic acid (PLGA) on bone regeneration in a rat calvarial defect. Surgical implantation of chitosan membranes resulted in enhanced local bone formation at both 2 and 8 weeks. In conclusion, the chitosan membrane coated with PLGA had a significant potential to induce bone formation in the rat calvarial defect model. Within the selected PLGA dose range and observation intervals, there app
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