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Young-Je Son

Seoul National University · Medicine

About the Lab

Professor Young-Je Son's research lab specializes in cerebrovascular diseases, with a primary focus on moyamoya disease (MMD) and cerebrovascular revascularization. The lab investigates long-term outcomes, surgical techniques, and risk factors for stroke recurrence in symptomatic MMD patients, emphasizing perioperative complications and prognostic indicators. Their work integrates clinical, angiographic, and hemodynamic assessments to optimize stroke prevention strategies.

moyamoya diseasecerebrovascular revascularizationstroke preventionangiographic outcomesperioperative complications

Research Overview

Papers
82
Total Citations
1,786
Papers (5y)
14
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
14total
2019
2022
2023
2024
2025
Citations per year (5y)
43total
20192022202320242025

Selected Papers

15
1
Article|188 citations·2014
Long-Term Outcomes After Combined Revascularization Surgery in Adult Moyamoya Disease
Won‐Sang Cho, Jeong Eun Kim, Chang Hyeun Kim, Seung Pil Ban, Hyun‐Seung Kang, Young‐Je Son, Jae Seung Bang, Chul‐Ho Sohn, Jin Chul Paeng, Chang Wan Oh
SJR Q1FWCI 9.2Stroke

Combined revascularization surgery resulted in satisfactory long-term improvement in clinical, angiographic, and hemodynamic states and prevention of recurrent stroke.

RheumatologyMedicine
2
Review|178 citations·2017
Meta-analysis of the surgical outcomes of symptomatic moyamoya disease in adults
Jin Pyeong Jeon, Jeong Eun Kim, Won‐Sang Cho, Jae Seung Bang, Young‐Je Son, Chang Wan Oh
SJR Q1FWCI 12.8Journal of neurosurgery

OBJECTIVE The purpose of this study was to evaluate treatment outcomes of future stroke prevention, perioperative complications, and angiographic revascularization in adults with symptomatic moyamoya disease (MMD) according to treatment modalities and surgical techniques. METHODS A systemic literature review was performed based on searches of the PubMed, Embase, and Cochrane Central databases. A fixed-effects model was used in cases of heterogeneity less than 50%. Publication bias was determined

RheumatologyMedicine
3
Article|117 citations·2010
Analysis of Complications Following Decompressive Craniectomy for Traumatic Brain Injury
Seung Pil Ban, Young‐Je Son, Hee‐Jin Yang, Yeong Seob Chung, Sang Hyung Lee, Dae Hee Han
SJR Q2FWCI 4.9Journal of Korean Neurosurgical SocietyOA

A poor GCS score (≤ 8) and an age of ≥ 65 were found to be related to the occurrence of one of the above-mentioned complications. These results should help neurosurgeons anticipate these complications, to adopt management strategies that reduce the risks of complications, and to improve clinical outcomes.

NeurologyMedicine
4
Article|103 citations·2012
Analysis of the factors influencing bone graft infection after cranioplasty
Chang-Hyun Lee, Young Sub Chung, Sang Hyung Lee, Hee‐Jin Yang, Young‐Je Son
SJR Q1FWCI 5.7The Journal of Trauma: Injury, Infection, and Critical Care

Prognostic/therapeutic study, level IV.

NeurologyMedicine
5
Article|92 citations·2006
Therapeutic strategy for large vestibular schwannomas
Chul‐Kee Park, Hee‐Won Jung, Jeong Eun Kim, Young‐Je Son, Sun Ha Paek, Dong Gyu Kim
SJR Q1FWCI 2.0Journal of Neuro-Oncology
EpidemiologyMedicine
6
Article|86 citations·2014
The natural clinical course of hemodynamically stable adult moyamoya disease
Won‐Sang Cho, Young Seob Chung, Jeong Eun Kim, Jin Pyeong Jeon, Young‐Je Son, Jae Seung Bang, Hyun‐Seung Kang, Chul‐Ho Sohn, Chang Wan Oh
SJR Q1FWCI 3.3Journal of neurosurgeryOA

There was no statistically significant difference in the incidence of stroke in the different clinical groups; clinical status, however, was most severe in patients with hemorrhagic presentation. In patients who experienced stroke during the follow-up period, the stroke type tended to correspond to their initial presentation. Close follow-up is needed in patients with thyroid disease and a family history of MMD.

RheumatologyMedicine
7
Article|62 citations·2014
A risk factor analysis of prospective symptomatic haemorrhage in adult patients with cerebral cavernous malformation
Jin Sue Jeon, Jeong Eun Kim, Young Seob Chung, Sohee Oh, Jun Hyong Ahn, Won‐Sang Cho, Young‐Je Son, Jae Seung Bang, Hyun‐Seung Kang, Chul‐Ho Sohn, Chang Wan Oh
SJR Q1FWCI 1.9Journal of Neurology Neurosurgery & PsychiatryOA

Prior symptomatic haemorrhage and MR appearance could be related to prospective symptomatic CM haemorrhage in adults. A prospective multicentre observational study is necessary to confirm our results.

NeurologyMedicine
8
Article|55 citations·2013
A retrospective analysis on the natural history of incidental small paraclinoid unruptured aneurysm
Jin Seok Jeon, Jun Hyong Ahn, Wooseong Huh, Young‐Je Son, Jungsik Bang, H.-S. Kang, Chul‐Ho Sohn, Chang Wan Oh, O-Ki Kwon, Jin-Ah Kim
SJR Q1FWCI 3.5Journal of Neurology Neurosurgery & Psychiatry

Although incidental small paraclinoid UIAs have a relatively lower rupture and growth risk, patients with high-risk factors, including aneurysm ≥4 mm, HTN, arterial branch-related aneurysms, and multiple aneurysms must be monitored closely. The limitation of the retrospective nature of this study should be taken into consideration.

NeurologyMedicine
9
Article|53 citations·2016
Incidence and risk factors of intracranial aneurysm: A national cohort study in Korea
Tackeun Kim, Heeyoung Lee, Soyeon Ahn, O-Ki Kwon, Jae Seung Bang, Gyojun Hwang, Jeong Eun Kim, Hyun‐Seung Kang, Young‐Je Son, Won‐Sang Cho, Chang Wan Oh
SJR Q1FWCI 3.4International Journal of Stroke

Background Estimations of the intracranial aneurysm incidence require long-term follow-up of a relatively large at-risk population; as a result, the incidence remains largely unknown. Aims To investigate the national incidence of intracranial aneurysm in a Korean population. Methods After excluding 18,604 potential subjects with a previous history of stroke (I6x.x), 998,216 subjects were included in this observational cohort. The primary endpoint was the earliest date of diagnosis of either unru

NeurologyMedicine
10
Article|51 citations·2012
Surgical Outcome of Percutaneous Endoscopic Interlaminar Lumbar Diskectomy for Recurrent Disk Herniation After Open Diskectomy
Chi Heon Kim, Chun Kee Chung, Tae-Ahn Jahng, Hee‐Jin Yang, Young‐Je Son
FWCI 3.0Journal of Spinal Disorders & Techniques

PEID with dissection of the scar tissue from the medial facet joint rather than from the neural tissue may be an effective alternative surgical method for recurrent disk herniation.

Pathology and Forensic MedicineMedicine
11
Article|49 citations·2017
Natural History and Risk Factor of Recurrent Hemorrhage in Hemorrhagic Adult Moyamoya Disease
Kang Min Kim, Jeong Eun Kim, Won‐Sang Cho, Hyun‐Seung Kang, Young‐Je Son, Moon Hee Han, Chang Wan Oh
SJR Q1FWCI 4.2Neurosurgery

During the follow-up period, recurrent hemorrhagic events continued to increase and deteriorated the patients' neurological conditions. The presence of intraventricular hemorrhage was a significant risk factor of recurrent hemorrhage.

RheumatologyMedicine
12
Article|43 citations·2010
The effect of brain atrophy on outcome after a large cerebral infarction
S. H. Lee, Chang Wan Oh, J. H. Han, Chae‐Yong Kim, O-Ki Kwon, Young‐Je Son, Hee‐Joon Bae, Moon‐Ku Han, Young Seob Chung
SJR Q1FWCI 0.6Journal of Neurology Neurosurgery & Psychiatry

Brain atrophy may have an association with clinical outcome after a large stroke by a trend of saving patients from an MCO but also by interfering with their functional recovery.

EpidemiologyMedicine
13
Article|41 citations·2006
Clinical analysis of vertebrobasilar dissection
Changhyun Kim, Young‐Je Son, Sun Ha Paek, Moon Hee Han, Jin-Ah Kim, Young Seob Chung, B.J. Kwon, Chang Wan Oh, Dae Hee Han
SJR Q1FWCI 2.4Acta Neurochirurgica
NeurologyMedicine
14
Article|20 citations·2007
IMAGE-GUIDED SURGERY FOR TREATMENT OF UNRUPTURED MIDDLE CEREBRAL ARTERY ANEURYSMS
Young‐Je Son, Dae Hee Han, Jeong Eun Kim
SJR Q2FWCI 1.3Operative Neurosurgery

With the aid of navigation, we were able to easily locate MCA aneurysms and perform minimally invasive surgeries such as mini-craniotomies, tailored sylvian dissections, and successful clippings of unruptured MCA aneurysms. In addition, we obtained satisfactory cosmetic results.

NeurologyMedicine
15
Article|17 citations·1999
Comparison of localizing values of various diagnostic tests in non-lesional medial temporal lobe epilepsy
Young‐Je Son, Chun Kee Chung, Sang-Kun Lee, Kee Hyun Chang, Dong Soo Lee, Yung Nahn Yi, Hyun Jib Kim
SJR Q2FWCI 1.0SeizureOA
Psychiatry and Mental healthMedicine

Research Areas

NeurologyRheumatologyPulmonary and Respiratory MedicineEpidemiologyRadiology, Nuclear Medicine and ImagingPathology and Forensic Medicine

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