Seoul National University · Medicine
Professor Jeong Ho Park's research lab focuses on translational biomedical research with a strong emphasis on infectious disease immunology and neuroimmunological disorders. The lab investigates innovative vaccination strategies, particularly in ovo prime-boost immunization against avian pathogens like infectious bursal disease virus, while exploring host immune modulators such as chicken cytokines as adjuvants. In parallel, the lab explores rare neuroimmunological conditions such as neuro-Behçet’s disease, emphasizing clinical phenotypes, diagnostic challenges, and treatment responses. The integration of clinical case studies with immunological and virological research highlights the lab’s commitment to improving health outcomes in both veterinary and human medicine.
Figures are computed from collected data and may differ slightly.
The aim of this study was to examine the efficacy of in ovo prime-boost vaccination against infectious bursal disease virus (IBDV) using a DNA vaccine to prime in ovo followed by a killed-vaccine boost post hatching. In addition, the adjuvant effects of plasmid-encoded chicken interleukin-2 and chicken interferon-gamma were tested in conjunction with the vaccine. A plasmid DNA vaccine (pcDNA-VP243) encoding the VP2, VP4, and VP3 proteins of the very virulent IBDV (vvIBDV) SH/92 strain was inject
We report a rare case of neuro-Behcet's disease (NBD) presenting as an inflammatory pseudotumor in the brain. A 52-year-old woman was evaluated for subacute dizziness and headache. Brain magnetic resonance (MR) imaging showed a right cerebellar mass, which disappeared 2 weeks later. After a year, recurrent mucocutaneous manifestations of Beh et's disease were observed. Immunosuppressant and steroid maintenance treatment were started. She experienced two more neurologic attacks and brain MR imagi
The KOHCAR has significantly contributed to improving OHCA survival rates in South Korea; however, the COVID-19 pandemic has posed challenge. To address the post-pandemic survival rate decline, there is a need to enhance data utilization, expand data sources, and tailor communication with diverse stakeholders.
A longer TTI adversely affected the likelihood of a good neurological recovery in OHCA patients without prehospital ROSC. This negative effect was more prominent in short STI group.
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