Tae Hyun Choi

The number of patients requiring flat bone transplantation continues to increase worldwide. Cell transplantation has been successfully applied clinically; however, it causes another defect site and the time requirements to harvest cells and expand them are considerable. In this study, KLD12/KLD12-SP (KLD12+KLD12-substance P [SP]) was designed to mimic endogenous tissue-healing processes. The structures of KLD12, KLD12-SP, and KLD12/KLD12-SP were observed by transmission electron microscopy and c

Ischemia-reperfusion injury is a phenomenon that occurs when tissues are subjected to ischemia for a variable period of time, and then reperfused. Inflammatory reaction has been implicated as one of the most important mechanism of ischemia-reperfusion injury. The purpose of this study was to evaluate the anti-inflammatory effects of anthocyanins from black soybean seed coat on keratinocytes in vitro and ischemia-reperfusion injury in vivo. We investigated the inhibition, by anthocyanins, of the

It is possible to correctly identify both outpatients and inpatients and also reduce the unnecessary cost of patient verification by using the mobile facial recognition app with great accuracy. Our mobile app can provide valuable aid to patient verification, including when the patient is unconscious, as an alternative identification method.

참여 및 숙의제도의 활용이 증가하면서 이러한 제도에 참여하는 시민들의 대표성의 한계와, 그에 따른 공적 의사결정의 정당성에 대한 비판이 증가하여왔다. 행정의 다양한 층위와 영역에서 활용되는 참여 및 숙의제도를 통한 공적 의사결정의 정당성을 확보하려면 이 제도의 대표성 문제를 이론적으로 해결해야 한다. 이 논문의 목적은 민주주의 행정 제도에서 대표성의 다양한 의미를 비판적으로 검토하고, 대의민주주의와 참여민주주의의 대표성의 장단점을 고려한 통합적인 제도 설계 접근을 제안하는 것이다. 이를 위해 우선 묘사적/통계적 대표성, 반응적/선출적 대표성 등 대표 구성과 책임의 원리에 따른 대표성의 다면성을 비판적으로 검토함으로써 대표성에 대한 복합적 접근이 필요함을 제시하였다. 다음으로 참여 및 숙의제도에서 대표성에 대한 다섯 가지 주요한 비판을 검토하여 그 정당성을 평가하고, 이를 최근 실행되었던 신고리 5･6호기 공론화위원회 사례에 적용하여 대표성의 실천적인 문제들을 검토하였다. 마지막으로

Anthocyanins are known to have antioxidant and antiinflammatory effects. We hypothesized that anthocyanins would enhance wound healing in Sprague-Dawley rats. The purpose of this study was to evaluate our hypothesis and investigate the mechanism of wound healing enhancement. The cytoprotective effect of an immortalized epidermal keratinocyte cell line (HaCaT) and human neonatal dermal fibroblasts in response to various concentrations of anthocyanins was determined. Vascular endothelial growth fa

A bioabsorbable polymeric bone plate enabled with both diagnostic and therapeutic functionalities (radiopacity and sustained drug release, respectively) is proposed. To this end, a drug-inorganic nanohybrid (RS-LDH) is examined as a theranostic agent by intercalating an anti-resorptive bone remodeling drug, risedronate (RS) into a layered double hydroxide (LDH) via an ion-exchange reaction. The RS-LDH is prepared as a sheet with a biodegradable polymer, poly(lactic-co-glycolic acid), and is then

We aimed to investigate the association of circulatory senescence-associated secretory phenotypes (SASPs) produced by senescent cells with chronological and menopausal age in women aged 45 years or more. The proteomic profiles for 32 SASP factors of plasma samples were measured in 76 healthy postmenopausal women aged 46-82 years from the Korean Genome and Epidemiology Study Cardiovascular Disease Association Study (KoGES-CAVAS). We assessed the association between the SASP factors and aging indi