Yonsei University · Medicine
Professor Yong Wook Kim's research lab focuses on translational and clinical neuroscience, with a strong emphasis on understanding the neural mechanisms underlying consciousness and neuropsychiatric disorders following brain injury. The lab investigates pharmacological responses to treatments such as methylphenidate in patients with impaired consciousness, explores neuroimaging correlates of post-stroke depression, and examines the role of specific brain regions in cognitive and affective sequelae after stroke. Additionally, the lab contributes to the understanding of molecular mechanisms in cancer biology, particularly the regulation of telomerase activity by signaling pathways such as PKC.
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Telomerase, a ribonucleoprotein reverse transcriptase that extends telomeres of eukaryotic chromosomes is repressed in normal somatic cells but is activated during development and neoplasia. The regulation mechanism of telomerase activity in cancer cells is not clearly known. In this report, a possible affect of PKC on telomerase activity was examined using HeLa and CUMC-6 cervical cancer cell lines. Exposure of cells to PKC inhibitor, bisindolylmaleimide I and Gö6976, and high levels of PKC act
The purpose of this paper is to examine the current implementation of inclusive education in South Korea and discuss its challenges. The history of special education is first described followed by an introduction to policies relevant to special and inclusive education. Next, a critical discussion of the state of inclusive education follows built upon the basis of perceived benefits and challenges by teachers involved in implementing inclusive education. This discussion extends further to include
Our findings suggest that the posteromedial parietal cortex, which is part of the neural network for consciousness, may be the relevant structure for the pharmacological response to methylphenidate treatment in patients with impaired consciousness after acquired brain injury.
The persistent velocity autocorrelation, first discovered by Alder and Wainwright through molecular dynamic computations, is confirmed experimentally in gaseous air and argon for the first time. Analysis is based on hydrodynamic considerations.
Post-stroke depression (PSD) is the most common neuropsychological sequela of stroke and occurs in approximately one-third of all stroke survivors. However, there are no well-established predictors of PSD. Depression in stroke patients is correlated with unfavorable outcomes. Meta-analyses of the relationship between PSD and lesion location have yielded contradictory results and have not adequately addressed the impact of cerebellar lesions. Furthermore, other brain regions associated with depre
The nerve/tunnel index is unaffected by body indices or sex and thus may be a useful and objective standard for diagnosing carpal tunnel syndrome.
A sling exercise with elastic bands leads to a reduction in pain and disability compared with a traditional stabilizing exercise, although traditional stabilizing exercise also shows good results in chronic LBP patients with clinical spinal instability. A sling exercise with an elastic band could be a useful treatment for chronic LBP with clinical spinal instability.
Abstract Even though the K orean experience with special education in the public education system is limited, inclusive education for special education needs ( SEN ) students has been at the center of attention at the national policy level since the mid‐1990s. Since then, K orean educators and administrators have put an emphasis on the revision and regulation of special education policies, guaranteeing the rights of SEN students to learn, and fostering the quality of teachers to strengthen inclu
Lesions causing pain are connected to a specific brain network that shows metabolic abnormalities and promise as a neuromodulation target. ANN NEUROL 2022;92:834-845.
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