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Byung Kyu Ahn

Hanyang University · Medicine

About the Lab

Professor Byung Kyu Ahn's research lab specializes in gastrointestinal and oncological diseases, with a strong focus on the molecular mechanisms underlying colorectal and gastric cancers. The lab investigates genetic and molecular markers such as microsatellite instability (MSI-H), somatic mutations, and protein expression (e.g., Smad4) to improve cancer prognosis and treatment strategies. Additionally, the lab explores clinical factors influencing disease progression and outcomes, including the role of gastroesophageal reflux disease (GERD) and proton pump inhibitor use in idiopathic pulmonary fibrosis, as well as risk factors for hemorrhoids in the population. The research integrates clinical data with next-generation sequencing (NGS) and pathological analysis to identify biomarkers and optimize surgical and medical interventions.

colorectal cancergastric cancermicrosatellite instabilitysomatic mutationssurgical outcomes

Research Overview

Papers
44
Total Citations
351
Papers (5y)
8
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
8total
2021
2023
2024
2025
2026
Citations per year (5y)
43total
20212023202420252026

Selected Papers

15
1
Article|59 citations·2016
Protective Effect of Proton Pump Inhibitor for Survival in Patients with Gastroesophageal Reflux Disease and Idiopathic Pulmonary Fibrosis
Chang Min Lee, Dong Ho Lee, Byung Kyu Ahn, Jae Jin Hwang, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim
SJR Q1Journal of Neurogastroenterology and MotilityOA

In Korean patients with IPF, the prevalence of GERD was lower than in other countries. PPI use for at least 4 months may have a protective effect against IPF-related mortality.

GastroenterologyMedicine
2
Article|38 citations·2018
Higher visceral fat area/subcutaneous fat area ratio measured by computed tomography is associated with recurrence and poor survival in patients with mid and low rectal cancers
Kang Hong Lee, Bo-Kyeong Kang, Byung Kyu Ahn
SJR Q2International Journal of Colorectal Disease
OncologyMedicine
3
Article|23 citations·2013
What is the optimal time for laparoscopic cholecystectomy in gallbladder empyema?
Yong Jin Kwon, Byung Kyu Ahn, Hwon Kyum Park, Kwang Soo Lee, Kyeong Geun Lee
SJR Q1Surgical Endoscopy
Pulmonary and Respiratory MedicineMedicine
4
Article|23 citations·2019
Comprehensive Analysis of Somatic Mutations in Colorectal Cancer With Peritoneal Metastasis
Ju‐Hee Lee, Byung Kyu Ahn, Seung Sam Baik, Kang Hong Lee
SJR Q2In VivoOA

A number of somatic mutations presumed to be relevant to colorectal cancer with peritoneal metastasis were identified in our study by NGS.

SurgeryMedicine
5
Article|22 citations·2010
Microsatellite Instability Is Associated with the Clinicopathologic Features of Gastric Cancer in Sporadic Gastric Cancer Patients
Shin Hyuk Kim, Byung Kyu Ahn, Young Su Nam, Joo Youn Pyo, Young‐Ha Oh, Kang Hong Lee
SJR Q1Journal of the Korean Gastric Cancer AssociationOA

PURPOSE: Replication error is an important mechanism in carcinogenesis. The microsatellite instability (MSI-H) of colorectal cancers is associated with the development of multiple cancers. The influence of MSI-H on the development of multiple gastric cancers in sporadic gastric cancer patients has not been defined. This study was performed to reveal the association between the clinicopathologic features and MSI in sporadic gastric cancers. MATERIALS AND METHODS: Between July 2004 and March 2009,

Pathology and Forensic MedicineMedicine
6
Article|19 citations·2011
Smad4 May Help to Identify a Subset of Colorectal Cancer Patients with Early Recurrence after Curative Therapy
Byung Kyu Ahn, Si‐Hyong Jang, Seung Sam Paik, Kang Hong Lee
Hepatogastroenterology

Smad4 protein is of no value in predicting recurrence after curative therapy in colorectal cancer, but it may be helpful in identifying a subset of patients with early recurrence after curative therapy.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
Article|18 citations·2012
Single-dose antibiotic prophylaxis is effective enough in colorectal surgery
Byung Kyu Ahn, Kang Hong Lee
SJR Q2ANZ Journal of Surgery

SD antibiotic prophylaxis with second-generation cephalosporin and metronidazole is equivalent to a three-dose prophylaxis for preventing SSI in elective colorectal surgery. But further study would be needed to clarify this because of the small number of participants.

SurgeryMedicine
8
Article|15 citations·2021
Socio-demographic factors and lifestyle associated with symptomatic hemorrhoids: Big data analysis using the National Health insurance Service-National Health screening cohort (NHIS-HEALS) database in Korea
Jineui Hong, Inah Kim, Jaechul Song, Byung Kyu Ahn
SJR Q2Asian Journal of SurgeryOA

The diagnostic and surgical incidence density was 13.9 and 5.7 per 1000 person-years, respectively. Hemorrhoids occurred most frequently in men in their 40s. The metropolitan area, high income level and alcohol consumption were associated with an increased frequency of hemorrhoids.

SurgeryMedicine
9
Article|14 citations·2021
Mechanical bowel preparation combined with oral antibiotics in colorectal cancer surgery: a nationwide population-based study
Jun Ho Lee, Byung Kyu Ahn, Jiin Ryu, Kang Hong Lee
SJR Q2International Journal of Colorectal Disease
SurgeryMedicine
10
Article|12 citations·2020
Prognostic value of B-cell linker protein in colorectal cancer
Jun Ho Lee, Ju‐Hee Lee, Byung Kyu Ahn, Seung Sam Paik, Kang Hong Lee
Pathology - Research and Practice
GeneticsMedicine
11
Review|12 citations·2021
Conservative treatment of uncomplicated right-sided diverticulitis: a systematic review and meta-analysis
Jun Ho Lee, Byung Kyu Ahn, Kang Hong Lee
SJR Q2International Journal of Colorectal Disease
SurgeryMedicine
12
Article|12 citations·2015
Chronic inflammatory demyelinating polyneuropathy-like neuropathy as an initial presentation of Crohn’s disease
Suji Kim, Seok‐Jae Kang, Ki‐Wook Oh, Byung Kyu Ahn, Hang Lak Lee, Dong Soo Han, Kiseok Jang, Young Seo Kim
SJR Q2BMC NeurologyOA

BACKGROUND: Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare complication of Crohn's disease (CD), and it is uncertain whether it is associated with CD itself or with its treatment. We describe a case of CIDP-like neuropathy as an initial symptom of CD. The neurologic symptoms of the patient which responded partially to intravenous immunoglobulin (IVIG) recovered after resection of the appendiceal CD. CASE PRESENTATION: A 17-year-old male had experienced three separate attacks

NeurologyMedicine
13
Article|10 citations·2012
Reconstruction of infected abdominal wall defects using latissimus dorsi free flap
Sang Wha Kim, Sang Chul Han, Kyu Tae Hwang, Byung Kyu Ahn, Jeong Tae Kim, Youn Hwan Kim
SJR Q2ANZ Journal of Surgery

Reconstruction using the latissimus dorsi myocutaneous flap, including muscle fascia structures, is a potential treatment option for severely infected large abdominal wall defects.

SurgeryMedicine
14
Article|10 citations·2005
Long-Term Graft Outcome of Living Donor Renal Transplantation: Single Center Experience
Oh Jung Kwon, Y.H. Kim, Byung Kyu Ahn, Chong Myung Kang, Jin Young Kwak
SJR Q3Transplantation Proceedings
Public Health, Environmental and Occupational HealthMedicine
15
Article|9 citations·2016
Loss of APAF-1 expression is associated with early recurrence in stage I, II, and III colorectal cancer
Byung Kyu Ahn, Sung Hoo Kim, Seung Sam Paik, Kang Hong Lee
SJR Q2Langenbeck s Archives of Surgery
Molecular BiologyBiochemistry, Genetics and Molecular Biology

Research Areas

SurgeryOncologyMolecular BiologyGastroenterologyPulmonary and Respiratory MedicinePathology and Forensic Medicine

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