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Chang-Woo Ryu

Kyung Hee University · Medicine

About the Lab

Professor Chang-Woo Ryu's research lab specializes in advanced neuroimaging techniques for the diagnosis and characterization of cerebrovascular diseases. The lab focuses on improving the accuracy of intracranial atherosclerotic plaque assessment using high-resolution vessel-wall MRI and diffusion-weighted imaging, with an emphasis on identifying vulnerable plaques and predicting stroke risk. Additionally, the lab investigates the role of multi-detector CT and MRI in evaluating intracranial aneurysms, stent-assisted coiling complications, and cerebral fat embolism. Their work bridges diagnostic radiology and clinical neuroscience to enhance early detection and intervention in cerebrovascular disorders.

vessel-wall MRIintracranial atherosclerosisdiffusion-weighted imagingcerebral fat embolismmulti-detector CT

Research Overview

Papers
194
Total Citations
3,433
Papers (5y)
38
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
38total
2022
2023
2024
2025
2026
Citations per year (5y)
82total
20222023202420252026

Selected Papers

15
1
Article|132 citations·2009
High Resolution Wall and Lumen MRI of the Middle Cerebral Arteries at 3 Tesla
Chang‐Woo Ryu, Geon‐Ho Jahng, Eui-Jong Kim, Woo‐Suk Choi, Dal-Mo Yang
SJR Q2Cerebrovascular Diseases

BACKGROUND: Although black-blood MRI (BB-MRI) can identify plaques in the cervical carotid arteries, this modality has not been applied in intracranial arteries. We imaged the lumina and walls of stenotic middle cerebral arteries (MCAs) in symptomatic and asymptomatic patients using high-resolution BB-MRI, in order to characterize vulnerable plaques and to determine the diagnostic accuracy of BB-MRI in MCA stenosis. METHODS: Multicontrast (T(1), T(2) and proton density)-weighted BB-MRIs were acq

Pulmonary and Respiratory MedicineMedicine
2
Review|129 citations·2015
Complications in Stent-Assisted Endovascular Therapy of Ruptured Intracranial Aneurysms and Relevance to Antiplatelet Administration: A Systematic Review
Chang‐Woo Ryu, Soonchan Park, Hee Sup Shin, Jun Seok Koh
SJR Q1American Journal of NeuroradiologyOA

On the basis of current evidence, complications of stent-assisted coiling for ruptured intracranial aneurysm may be affected by the method of antiplatelet administration.

NeurologyMedicine
3
Article|83 citations·2007
64 Multidetector-Row Computed Tomography for Preoperative Evaluation of Gastric Cancer
Dal Mo Yang, Hyun‐Cheol Kim, Wook Jin, Chang‐Woo Ryu, Jee Hee Kang, Chul Hi Park, Hyung Sik Kim, Dong Hae Jung
SJR Q3Journal of Computer Assisted Tomography

The 64 MDCT is a promising technique for the detection and preoperative staging of gastric cancer.

Pulmonary and Respiratory MedicineMedicine
4
Article|78 citations·2010
Analysis of aneurysm rupture in relation to the geometric indices: aspect ratio, volume, and volume-to-neck ratio
Chang‐Woo Ryu, O-Ki Kwon, Jun Seok Koh, Eui Jong Kim
SJR Q1Neuroradiology
NeurologyMedicine
5
Review|73 citations·2018
Vessel-Wall Magnetic Resonance Imaging of Intracranial Atherosclerotic Plaque and Ischemic Stroke: A Systematic Review and Meta-Analysis
Han Na Lee, Chang‐Woo Ryu, Seong Jong Yun
SJR Q2Frontiers in NeurologyOA

<b>Introduction:</b> Vessel-wall magnetic resonance imaging (MRI) has been suggested as a valuable tool for assessing intracranial arterial stenosis with additional diagnostic features. However, there is limited conclusive evidence on whether vessel-wall MR imaging of intracranial atherosclerotic plaques provides valuable information for predicting vulnerable lesions. We conducted this systematic review and meta-analysis to evaluate which characteristics of intracranial-plaque on vessel-wall MRI

Pulmonary and Respiratory MedicineMedicine
6
Review|72 citations·2017
Benefit of adding digital breast tomosynthesis to digital mammography for breast cancer screening focused on cancer characteristics: a meta-analysis
Seong Jong Yun, Chang‐Woo Ryu, Sun Jung Rhee, Jung Kyu Ryu, Ji Young Oh
SJR Q1Breast Cancer Research and Treatment
Pulmonary and Respiratory MedicineMedicine
7
Article|68 citations·2009
Persistent Falcine Sinus: Is It Really Rare?
Chang‐Woo Ryu
SJR Q1American Journal of NeuroradiologyOA

In contrast to previous reports, falcine sinuses were not rare in the adult population, and most falcine sinuses were not associated with a congenital anomaly or sinus occlusion. Knowledge and recognition of these falcine sinuses are useful and important during the interpretation of brain CTA.

NeurologyMedicine
8
Article|54 citations·2005
Cerebral fat embolism: diffusion-weighted magnetic resonance imaging findings
Chang‐Woo Ryu, D. H. Lee, T. K. Kim, S. J. Kim, H. S. Kim, J. H. Lee, Choong Gon Choi, Dae Chul Suh
SJR Q3Acta Radiologica

PURPOSE: To demonstrate the diffusion-weighted (DWI) magnetic resonance imaging (MRI) findings, and the follow-up MRI findings, of cerebral fat embolism in the acute stage. MATERIAL AND METHODS: The initial DWI and clinical findings of six patients with cerebral fat embolism were retrospectively evaluated. The finding of DWI with a b-value of 1000 s/mm2 (b=1000) was compared with that of DWI with a b-value of 0 s/mm2 (b=0). In three patients who underwent follow-up MRI, the interval change of th

Internal MedicineMedicine
9
Review|53 citations·2014
High-Resolution MRI of Intracranial Atherosclerotic Disease
Chang‐Woo Ryu, Hyo Sung Kwak, Geon‐Ho Jahng, Han Na Lee
SJR Q2NeurointerventionOA

Intracranial atherosclerotic disease (ICAD) causes up to 10% of all ischemic strokes, and the rate of recurrent vascular ischemic events is very high. Important predictors of vulnerability in atherosclerotic plaques include the degree of stenosis and the underlying plaque morphology. Vascular wall MRI can provide information about wall structures and atherosclerotic plaque components. High-resolution (HR)-MRI in ICAD poses a greater challenge in the neurologic fields, because a high in-plane res

Pulmonary and Respiratory MedicineMedicine
10
Article|38 citations·2007
Percutaneous direct puncture glue embolization of high-flow craniofacial arteriovenous lesions: a new circular ring compression device with a beveled edge.
Chang‐Woo Ryu, Susan Whang, Dae Chul Suh, S.-M. Kim, Y-J Jang, H.-J. Kim, M.-J. Kim, Shih‐Jen Chang, Jing Hong, S.J. Kim
PubMedOA

SUMMARY: The purpose of this study was to evaluate the efficacy of a newly designed circular ring compression device that allows safe and effective glue injection during preoperative embolization of high-flow superficial craniofacial arteriovenous malformations (AVMs). The device was used in 4 cases of craniofacial AVM with multiple feeding arteries and draining veins. It provided a safe glue injection route as well as effective compression of radiating multiple venous drainage routes.

NeurologyMedicine
11
Article|35 citations·2017
Alberta Stroke Program Early CT Score in the Prognostication after Endovascular Treatment for Ischemic Stroke: A Meta-analysis
Chang‐Woo Ryu, Hee Shup Shin, Soonchan Park, Sang Hyun Suh, Jun Seok Koh, Hye‐Yeon Choi
SJR Q2NeurointerventionOA

PURPOSE: The Alberta Stroke Program Early CT Score (ASPECTS) was devised to quantify the extent of early ischemic changes in the middle cerebral artery territory on brain CT. We performed a systematic review and meta-analysis of studies that presented clinical outcomes and baseline ASPECTS in ischemic stroke patients managed with endovascular methods to validate the use of ASPECTS for risk prognostication. MATERIALS AND METHODS: We searched the MEDLINE, EMBASE, and Cochran databases for observat

EpidemiologyMedicine
12
Article|34 citations·2014
Gadolinium Enhancement of Atherosclerotic Plaque in the Middle Cerebral Artery: Relation to Symptoms and Degree of Stenosis
Chang‐Woo Ryu, Geon‐Ho Jahng, Hee Sup Shin
SJR Q1American Journal of NeuroradiologyOA

Plaque enhancement was significantly higher in patients with symptomatic plaques and may have been affected by the degree of stenosis. A difference in plaque enhancement according to the degree of stenosis has implications for understanding the development of intracranial atherosclerotic plaques.

Pulmonary and Respiratory MedicineMedicine
13
Article|31 citations·2013
Microstructural Change of the Brain in Chronic Obstructive Pulmonary Disease: A Voxel-Based Investigation by MRI
Chang‐Woo Ryu, Geon‐Ho Jahng, Cheon Woong Choi, Hak Young Rhee, Min‐Ji Kim, Sun Mi Kim, Eui Jong Kim, Woo‐Suk Choi
SJR Q2COPD Journal of Chronic Obstructive Pulmonary DiseaseOA

BACKGROUND: Cognitive deficit is a common problem in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to prospectively evaluate if MRI can demonstrate microstructural volume loss and the diffusion anisotropic change in subjects with COPD, compared with cognitively normal (CN) subjects. METHODS: Six subjects with severe COPD, 13 with moderate COPD, and 12 CN subjects underwent isotropic volumetric T1-weighted imaging and diffusion tensor imaging (DTI). Voxel-b

Pulmonary and Respiratory MedicineMedicine
14
Article|31 citations·2015
White matter integrity associated with clinical symptoms in tinnitus patients: A tract-based spatial statistics study
Chang‐Woo Ryu, Moon Suh Park, Jae Yong Byun, Geon‐Ho Jahng, Soonchan Park
SJR Q1European Radiology
Sensory SystemsNeuroscience
15
Article|27 citations·2005
Extravasation of Intracranial Aneurysm During Computed Tomography Angiography
Chang‐Woo Ryu, Sang Joon Kim, Deok Hee Lee, Dae Chul Suh, Byung Duk Kwun
SJR Q3Journal of Computer Assisted Tomography

Two cases of contrast media extravasation of a ruptured aneurysm during computed tomography angiography (CTA) are described. The contrast media extravasation appeared as a highly attenuated twisted ribbon-like structure originating from the aneurysmal dome, and this mimicked a vascular structure. Because rebleeding of an aneurysm is accompanied by disastrous consequences, it is important to understand the imaging feature of active bleeding on CTA.

NeurologyMedicine

Research Areas

NeurologyRadiology, Nuclear Medicine and ImagingPulmonary and Respiratory MedicineEpidemiologyPsychiatry and Mental healthSurgery

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