Daesoo Kim
Korea Advanced Institute of Science and Technology · Neuroscience
About the Lab
Professor Daesoo Kim's research lab specializes in neuroengineering and translational neuroscience, focusing on the development of implantable bioelectronic devices for neuromodulation and the investigation of ion channels and metabolic pathways in neurological disorders. The lab integrates flexible electronics, such as piezoelectric energy harvesters and microelectrode arrays (e.g., iWEBS), to enable long-term, stable brain-computer interfaces in freely moving animals. Research also spans molecular mechanisms of pain modulation, particularly T-type calcium channels in thalamic processing, and the role of metabolic regulators like NQO1 in aging and neurodegeneration. Additionally, the lab explores the neurobiological basis of movement disorders, including dystonia, through serotonin receptor modulation.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15A self-powered deep brain stimulation has been demonstrated by a flexible piezoelectric PIMNT energy harvester to induce behavioural changes in a mouse.
Sensations from viscera, like fullness, easily become painful if the stimulus persists. Mice lacking alpha1G T-type Ca2+ channels show hyperalgesia to visceral pain. Thalamic infusion of a T-type blocker induced similar hyperalgesia in wild-type mice. In response to visceral pain, the ventroposterolateral thalamic neurons evokeda surge of single spikes, which then slowly decayed as T type-dependent burst spikes gradually increased. In alpha1G-deficient neurons, the single-spike response persiste
This study investigates pricing and return policies under various supply contracts in a closed-loop supply chain in which a supplier has more bargaining power than a retailer. We develop integrated supply contract models based on the principal–agent paradigm. Specifically, the supplier with more bargaining power devises a supply contract, acting as a Stackelberg leader. Then, given the contract offer, the retailer decides on pricing and return policies which affect consumers’ demand and return b
Spatiotemporal mapping of neural interactions through electrocorticography (ECoG) is the key to understanding brain functions and disorders. For the entire brain cortical areas, this approach has been challenging, especially in freely moving states, owing to the need for extensive craniotomy. Here, we introduce a flexible microelectrode array system, termed iWEBS, which can be inserted through a small cranial slit and stably wrap onto the curved cortical surface. Using iWEBS, we measured dynamic
Research Areas
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