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Do Hun Lim

Sungkyunkwan University · Medicine

About the Lab

Professor Do Hun Lim's research lab specializes in radiation oncology, with a focus on optimizing radiotherapy techniques and treatment strategies for hepatocellular carcinoma (HCC), brain tumors, and prostate cancer. The lab investigates the role of neoadjuvant and adjuvant radiotherapy, including stereotactic body radiation therapy (SBRT) and intensity-modulated radiation therapy (IMRT), to improve local control and survival outcomes. A key emphasis is on integrating advanced imaging and deep learning models to predict patient survival and personalize treatment planning.

radiotherapyhepatocellular carcinomaglioblastomaradiosensitizersdeep learning

Research Overview

Papers
361
Total Citations
7,720
Papers (5y)
54
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
54total
2022
2023
2024
2025
2026
Citations per year (5y)
191total
20222023202420252026

Selected Papers

15
1
Article|679 citations·2018
Oncological Benefits of Neoadjuvant Chemoradiation With Gemcitabine Versus Upfront Surgery in Patients With Borderline Resectable Pancreatic Cancer
Jin‐Young Jang, Youngmin Han, Hongeun Lee, Sun‐Whe Kim, Wooil Kwon, Kyung-Hun Lee, Do‐Youn Oh, Eui Kyu Chie, Jeong Min Lee, Jin Seok Heo, Joon Oh Park, Do Hoon Lim
SJR Q1Annals of SurgeryOA

OBJECTIVE: This study was performed to determine whether neoadjuvant treatment increases survival in patients with BRPC. SUMMARY BACKGROUND DATA: Despite many promising retrospective data on the effect of neoadjuvant treatment for borderline resectable pancreatic cancer (BRPC), no high-level evidence exists to support the role of such treatment. METHODS: This phase 2/3 multicenter randomized controlled trial was designed to enroll 110 patients with BRPC who were randomly assigned to gemcitabine-

OncologyMedicine
2
Article|181 citations·2005
Three‐dimensional conformal radiotherapy for portal vein thrombosis of hepatocellular carcinoma
Dae Yong Kim, Won Park, Do Hoon Lim, Joon Hyoek Lee, Byung Chul Yoo, Seung Woon Paik, Kwang Cheol Kho, Tae Hyun Kim, Yong Chan Ahn, Seung Jae Huh
SJR Q1Cancer

BACKGROUND: Portal vein thrombosis (PVT) is a common complication in patients with advanced-stage hepatocellular carcinoma (HCC). The authors evaluated the impact of radiotherapy (RT) for PVT of HCC and analyzed the dose-response relation between RT and PVT. METHODS: Between March 1995 and December 2003, 59 patients diagnosed as HCC with PVT were included. The inclusion criteria were unresectable tumor with thrombosis in the main or first branch of the portal vein, liver function of Child-Pugh C

HepatologyMedicine
3
Article|168 citations·2005
Local radiotherapy for patients with unresectable hepatocellular carcinoma
Won Park, Do Hoon Lim, Seung Woon Paik, Kwang Cheol Koh, Moon Seok Choi, Cheol Keun Park, Byung Chul Yoo, Jeong Eun Lee, Min Kyu Kang, Young Je Park, Hee Rim Nam, Yong Chan Ahn
SJR Q1International Journal of Radiation Oncology*Biology*Physics
HepatologyMedicine
4
Article|60 citations·2010
Early Three-Dimensional Conformal Radiotherapy for Patients With Unresectable Hepatocellular Carcinoma After Incomplete Transcatheter Arterial Chemoembolization
Dongryul Oh, Do Hoon Lim, Hee Chul Park, Seung Woon Paik, Kwang Cheol Koh, Joon Hyoek Lee, Moon Seok Choi, Byung Chul Yoo, Hyo Keun Lim, Won Jae Lee, Hyunchul Rhim, Sung Wook Shin
SJR Q3American Journal of Clinical Oncology

Early 3D-CRT for HCC unresponsive to 1 or 2 cycles of TACE resulted in a 62.8% tumor response rate and relatively high complete response rates (20.9%) with acceptable toxicity. This study shows that the application of 3D-CRT could be considered for patients with incomplete TACE.

HepatologyMedicine
5
Article|36 citations·2015
Effects of adjuvant radiotherapy on completely resected gastric cancer: A radiation oncologist’s view of the ARTIST randomized phase III trial
Jeong Il Yu, Do Hoon Lim, Do Hoon Lim, Yong Chan Ahn, Jeeyun Lee, Won Ki Kang, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Ho Yeong Lim, Seung Tae Kim
SJR Q1Radiotherapy and Oncology
Pulmonary and Respiratory MedicineMedicine
6
Article|35 citations·2007
The Role of Adjuvant Radiotherapy in Microscopic Tumor Control After Extrahepatic Bile Duct Cancer Surgery
Dongryul Oh, Do Hoon Lim, Jin Seok Heo, Seong‐Ho Choi, Dong Wook Choi, Yong Chan Ahn, Won Park, Seung Jae Huh
SJR Q3American Journal of Clinical Oncology

Lymph node metastasis was a poor prognostic factor and adjuvant RT may be useful in patients with microscopic residual tumor. However, because there were high loco-regional recurrences, additional study is needed to determine more effective RT such as increased RT dose or use of radiosensitizers.

SurgeryMedicine
7
Article|35 citations·2009
Predictive factors of gastroduodenal toxicity in cirrhotic patients after three-dimensional conformal radiotherapy for hepatocellular carcinoma
Haeyoung Kim, Do Hoon Lim, Seung Woon Paik, Byung Chul Yoo, Kwang Gheol Koh, Joon Hyoek Lee, Moon Seok Choi, Won Park, Hee Chul Park, Seung Jae Huh, Doo Ho Choi, Yong Chan Ahn
SJR Q1Radiotherapy and Oncology
HepatologyMedicine
8
Article|31 citations·2014
Efficacy of postoperative radiotherapy for high grade meningiomas
Yunseon Choi, Do Hoon Lim, Kyung-Il Jo, Do‐Hyun Nam, Ho Jun Seol, Jung-Il Lee
SJR Q1Journal of Neuro-Oncology
EpidemiologyMedicine
9
Article|29 citations·2020
Multi-Parametric Deep Learning Model for Prediction of Overall Survival after Postoperative Concurrent Chemoradiotherapy in Glioblastoma Patients
Han Gyul Yoon, Wonjoong Cheon, Sangwoon Jeong, Hye Seung Kim, Kyunga Kim, Heerim Nam, Youngyih Han, Do Hoon Lim
SJR Q1CancersOA

This study aimed to investigate the performance of a deep learning-based survival-prediction model, which predicts the overall survival (OS) time of glioblastoma patients who have received surgery followed by concurrent chemoradiotherapy (CCRT). The medical records of glioblastoma patients who had received surgery and CCRT between January 2011 and December 2017 were retrospectively reviewed. Based on our inclusion criteria, 118 patients were selected and semi-randomly allocated to training and t

Radiology, Nuclear Medicine and ImagingMedicine
10
Article|28 citations·2009
Optimal beam arrangement for stereotactic body radiation therapy delivery in lung tumors
Do Hoon Lim, Byong Yong Yi, A. Mirmiran, A. Dhople, Mohan Suntharalingam, W DˈSouza
SJR Q2Acta OncologicaOA

Based on the dosimetric criteria outlined in RTOG 0236, the treatment technique using non-coplanar static beams showed the most preferable results for SBRT of lung lesions.

RadiationPhysics and Astronomy
11
Article|28 citations·2008
A New Suggestion for the Radiation Target Volume After a Subtotal Gastrectomy in Patients With Stomach Cancer
Heerim Nam, Do Hoon Lim, Sung Kim, Won Ki Kang, Tae Sung Sohn, Jae Hyung Noh, Yong Il Kim, Chan Hyung Park, Chul Keun Park, Yong Chan Ahn, Seung Jae Huh
SJR Q1International Journal of Radiation Oncology*Biology*Physics
Pulmonary and Respiratory MedicineMedicine
12
Article|23 citations·2015
Prognostic Value of Ki-67 Labeling Index and Postoperative Radiotherapy in WHO Grade II Meningioma
Yunseon Choi, Do Hoon Lim, Jeong Il Yu, Kyung-Il Jo, Do‐Hyun Nam, Ho Jun Seol, Jung-Il Lee, Doo‐Sik Kong, Yeon‐Lim Suh, Heerim Nam
SJR Q3American Journal of Clinical Oncology

OBJECTIVE: This study was performed to determine the clinical significance of the Ki-67 labeling index (LI) for local control (LC) in patients with World Health Organization (WHO) grade II meningioma. We also tried to discern the effect of postoperative radiotherapy (PORT) on LC depending upon the Ki-67 LI value. MATERIALS AND METHODS: The medical records and values of Ki-67 LIs were retrospectively reviewed for 50 patients who underwent surgical resection of intracranial WHO grade II meningioma

EpidemiologyMedicine
13
Article|22 citations·2015
The effects of radiation therapy on height and spine MRI characteristics in children with neuroblastoma
Jeong Il Yu, Do Hoon Lim, Sang Hoon Jung, Ki Woong Sung, So‐Young Yoo, Heerim Nam
SJR Q1Radiotherapy and Oncology
NeurologyMedicine
14
Article|22 citations·2014
Intensive chemotherapy followed by reduced-dose radiotherapy for biopsy-proven CNS germinoma with elevated beta-human chorionic gonadotropin
Do Hoon Lim, Keon Hee Yoo, Na Hee Lee, Soo Hyun Lee, Ki Woong Sung, Hong Hoe Koo, Ji Hye Kim, Yeon‐Lim Suh, Yoo‐Sook Joung, Hyung Jin Shin
SJR Q1Journal of Neuro-Oncology
GeneticsMedicine
15
Article|21 citations·2012
The Efficacy of High-dose 3-Dimensional Conformal Radiation Therapy in Patients With Small Hepatocellular Carcinoma Not Eligible for Other Local Modalities
Do Hoon Lim, Hyebin Lee, Hee Chul Park, Jung Ae Lee, Sang Won Kim, Byung Chul Yoo, Kwang Cheol Koh, Joon Hyeok Lee, Moon Seok Choi, Geum Youn Gwak, Seung Woon Paik
SJR Q3American Journal of Clinical Oncology

High-dose 3D-CRT for small HCC <5 cm showed favorable local control and overall survival without serious complications. RT might be an effective local modality in patients with small HCC not eligible for other local modalities.

HepatologyMedicine

Research Areas

Pulmonary and Respiratory MedicineGeneticsNeurologyHepatologySurgeryRadiation

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