Dong Pyo Kim

In chemical synthesis, rapid intramolecular rearrangements often foil attempts at site-selective bimolecular functionalization. We developed a microfluidic technique that outpaces the very rapid anionic Fries rearrangement to chemoselectively functionalize iodophenyl carbamates at the ortho position. Central to the technique is a chip microreactor of our design, which can deliver a reaction time in the submillisecond range even at cryogenic temperatures. The microreactor was applied to the synth

Abstract Metal doped core–shell Metal‐Organic Frameworks@Covalent Organic Frameworks (MOFs@COFs) are presented as a novel platform for photocatalysis. A palladium (Pd) doped MOFs@COFs in the form of Pd/TiATA@LZU1 shows excellent photocatalytic performance for tandem dehydrogenation and hydrogenation reactions in a continuous‐flow microreactor and a batch system, indicating the great potential of the metal doped MOFs@COFs as a multifunctional platform for photocatalysis. Explanations for the perf

Transparent substrates are widely used for optical applications from lenses for personal and sports eyewear to transparent displays and sensors. While these substrates require excellent optical properties, they often suffer from a variety of environmental challenges such as excessive fogging and surface contamination. In this work, it is demonstrated that a wet-style superhydrophobic coating, which simultaneously exhibits antifogging, antireflective, and self-cleaning properties, can be prepared

Functional bio-MOF hollow spheres with controlled size in the 35–2000 μm range were successfully synthesized by interfacial reaction using a continuous-flow droplet microfluidic system in a single step and one-flow strategy. The architecture of MIL-88A frameworks was extended from single-shell to double-shell hollow spheres. Moreover, various functional nanoparticles (silica, cobalt, and UiO-66(Zr) MOF) were directly encapsulated in the single-shell hollow spheres, while maintaining the function

A fierce dog: A method for the continuous in-situ on-demand generation, separation, and reaction of diazomethane in a dual-channel microreactor has been developed (see picture; Diazald=N-methyl-N-nitroso-p-toluenesulfonamide). The microchemical system allows a variety of diazomethane reactions to be performed without the most common problems of preparation, handling, transfer, and decomposition. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such do

Abstract This study presents a simple synthetic approach for the in situ preparation of monodisperse hybrid Janus microspheres (HJM) having organic and inorganic parts in a PDMS‐based microfluidic device. Based on the mechanism of shear‐force‐driven break‐off, merged droplets of two photocurable oligomer solutions having distinctive properties are generated into an immiscible continuous phase. Functionalized perfluoropolyether (PFPE) as the organic phase and hydrolytic allylhydridopolycarbosilan

Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA = N,N-diisopropylethylamine.

Despite many efforts on the synthesis of inorganic nanomaterials with uniform structure and narrow size distribution in a fast and continuous way, it is still a critical challenge in the chemistry research community due to the uncontrollable mass and heat transfer and the harsh experimental conditions of high temperature and pressure. Here we report a droplet- and ionic liquid-assisted microfluidic (DIM) synthesis method, which takes full advantage of both ionic liquids and droplet-assisted micr

A microreactor consisting of two microfluidic channels that are separated by a thin membrane is devised for intimate contact between gas and liquid phases. Gas flowing in one microchannel can diffuse into the liquid flowing in the other microchannel through the thin membrane. An oxidative Heck reaction carried out in the dual-channel (DC) microreactor, in which gaseous oxygen plays a key role in the catalytic reaction, shows the significant improvement that can be made over the traditional batch

A transparent dual-channel microreactor with highly enhanced contact area-to-volume ratio was fabricated for efficient photosensitized oxygenations. The dual-channel microreactor shielded with polyvinylsilazane (PVSZ) consisting of an upper channel for liquid flow and a lower channel for O(2) flow, allows sufficient phase contact along the parallel channels through a gas permeable PDMS membrane for maintaining the O(2) saturated solution. Under full exposure of reactants to light, the reactions

Abstract Hydrophobization of metal‐organic frameworks (MOFs) is important to push forward their practical use and thus has attracted increasing interest. In contrast to the previous reports, which mainly focused on the modification of organic ligands in MOFs, herein, we reported a novel strategy to decorate the metal‐oxo nodes of MOFs with phenylsilane to afford super‐hydrophobic NH 2 ‐UiO‐66(Zr), which shows highly improved base resistance and holds great promise in versatile applications, such

Abstract Simultaneous capture of carbon dioxide (CO 2 ) and its utilization with subsequent work-up would significantly enhance the competitiveness of CO 2 -based sustainable chemistry over petroleum-based chemistry. Here we report an interfacial catalytic reaction platform for an integrated autonomous process of simultaneously capturing/fixing CO 2 in gas–liquid laminar flow with subsequently providing a work-up step. The continuous-flow microreactor has built-in silicon nanowires (SiNWs) with

An integrated microfluidic system for multiple reactions and separations of hazardous ethyl diazoacetate is presented. The integrated techniques include: a droplet technique for liquid–liquid and/or gas–liquid separation and in situ generation of the toxic reagent, a dual channel membrane technique based on a cheap polymeric microseparator for liquid–liquid separation, and a capillary microreactor for carrying out cascade reactions in a sequential and continuous manner.