Donggeun Lee
Seoul National University · Materials Science
About the Lab
Professor Donggeun Lee's research lab focuses on plant stress biology and regenerative medicine, with a central emphasis on understanding molecular mechanisms underlying root development and drought tolerance in crops. The lab investigates transcriptional regulators such as OsERF71 and OsNAC6 to decipher how plants reprogram root architecture under abiotic stress, aiming to enhance crop resilience through biotechnological applications. In parallel, the lab pioneers the clinical translation of nanomaterials, notably detonation nanodiamonds (NDs), by integrating them into biomaterials like ND-embedded gutta percha for improved root canal therapy. This interdisciplinary approach bridges plant developmental biology and nanomedicine to address global challenges in agriculture and dentistry.
Research Overview
Research Output Trend
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Selected Papers
15Plant responses to drought stress require the regulation of transcriptional networks via drought-responsive transcription factors, which mediate a range of morphological and physiological changes. AP2/ERF transcription factors are known to act as key regulators of drought resistance transcriptional networks; however, little is known about the associated molecular mechanisms that give rise to specific morphological and physiological adaptations. In this study, we functionally characterized the ri
Expansin is a family of proteins that catalyze long-term expansion of cell walls and has been considered a principal protein that affects cell expansion in plants. We have identified the first root-specific expansin gene in soybean (Glycine max), GmEXP1, which may be responsible for root elongation. Expression levels of GmEXP1 were very high in the roots of 1- to 5-d-old seedlings, in which rapid root elongation takes place. Furthermore, GmEXP1 mRNA was most abundant in the root tip region, wher
Drought has a serious impact on agriculture worldwide. A plant's ability to adapt to rhizosphere drought stress requires reprogramming of root growth and development. Although physiological studies have documented the root adaption for tolerance to the drought stress, underlying molecular mechanisms is still incomplete, which is essential for crop engineering. Here, we identified OsNAC6-mediated root structural adaptations, including increased root number and root diameter, which enhanced drough
Root canal therapy (RCT) represents a standard of treatment that addresses infected pulp tissue in teeth and protects against future infection. RCT involves removing dental pulp comprising blood vessels and nerve tissue, decontaminating residually infected tissue through biomechanical instrumentation, and root canal obturation using a filler material to replace the space that was previously composed of dental pulp. Gutta percha (GP) is typically used as the filler material, as it is malleable, i
Plant organs are generated from meristems throughout development. Patterning and elaboration of organ primordia occur as a result of organized cell division and expansion, processes that are likely to be controlled, in part, by meristem-derived signals. Communication between the meristem and lateral organs is crucial for meristem maintenance and organ patterning, and organ boundaries are thought to be important for mediating this communication. Arabidopsis thaliana LATERAL ORGAN FUSION1 (LOF1) e
Detonation nanodiamonds (NDs) are promising drug delivery and imaging agents due to their uniquely faceted surfaces with diverse chemical groups, electrostatic properties, and biocompatibility. Based on the potential to harness ND properties to clinically address a broad range of disease indications, this work reports the in-human administration of NDs through the development of ND-embedded gutta percha (NDGP), a thermoplastic biomaterial that addresses reinfection and bone loss following root c
Drought is the most serious problem that impedes crop development and productivity worldwide. Although several studies have documented the root architecture adaption for drought tolerance, little is known about the underlying molecular mechanisms. Our latest study demonstrated that overexpression of the OsERF71 in rice roots under drought conditions modifies root structure including larger aerenchyma and radial root growth, and thereby, protects the rice plants from drought stresses. The OsERF71
CO2 hydrogenation was carried out at 423 K and 600 KPa with PtCu/SiO2 catalyst. Formaldehyde rather than methanol was mainly produced, and platinum is believed to play an important role in the selective production of formaldehyde from CO2 hydrogenation. The optimum atomic ratio of Pt/Cu in the PtCu/SiO2 catalyst for the selective production of formaldehyde was 0.03. Copyright © 2001 John Wiley & Sons, Ltd.
Research Areas
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