En-Joo Jung
Seoul National University · Medicine
About the Lab
Professor En-Joo Jung's research lab focuses on epidemiological and translational studies linking environmental, lifestyle, and metabolic factors to chronic disease outcomes, particularly cancer, cardiovascular disease, and neurodegenerative disorders. The lab investigates the role of modifiable risk factors such as alcohol consumption, diabetes, air pollution (PM2.5 and ozone), and obesity in disease progression and mortality. It also explores natural compounds—such as those derived from Rhus verniciflua Stokes and Biota orientalis—for their neuroprotective and antifibrotic properties, emphasizing mechanisms involving oxidative stress and cellular signaling pathways. The lab integrates population-based epidemiology with in vitro and in vivo models to identify preventive strategies and therapeutic candidates.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Due to the aging population and tremendous changes in life style over the past decades, cancer has been the leading cause of death in Korea. The incidence rate of breast cancer is the second highest in Korea, and it has shown an annual increase of 6.8% for the past 6 years. The major risk factors of breast cancer in Korean women are as follows: Early menarche, late menopause, late full-term pregnancy (FTP), and low numbers of FTP. Height and body mass index increased the risk of breast cancer in
The present study supports the existence of a J-shaped association between alcohol consumption quantity and the risk of all-cause and cancer deaths. Heavy drinkers had an increased risk of death from cancer overall and liver and stomach cancer.
This study suggests that diabetes in lean people is more critical to CVD deaths than it is in obese people.
Antifibrotic effect of twelve diterpenes (1-12) from the 90% methanolic fraction of Biota orientalis leaves was evaluated employing HSC-T6 cells by assessing cell proliferation and morphological change. Among these diterpenes, totarol (8) and isopimara-8(14),15-dien-19-oic acid (9) dramatically reduced cell proliferation in dose- and time-dependent manner. Furthermore, treatment with these compounds resulted in the different pattern of morphological changes of HSC-T6 cells. Taken together, antip
The methanolic extract of Rhus verniciflua Stokes (RVS-T) and its fractions (RVS-H, RVS-C, RVS-E and RVS-B) showed significant neuroprotective activity against glutamate-induced toxicity in primary cultures of rat cortical cells. RVS-B, which showed the most potent neuroprotective activity, was further fractionated to yield RVS-B5. Treatment of cortical cells with the RVS-T, RVS-B and RVS-B5 reduced the cellular ROS level and restored the reduced activities of glutathione reductase and SOD induc
In our study, an increase in the number of deaths in the elderly population in accordance with the increase in the PM2.5 and ozone was found. The association found in our study could also influence socioeconomic burden. Future studies need to be performed in regards to younger population, as well as other air pollutants.
Abstract Objectives: To examine the association between alcohol consumption, types of beverages, alcohol amount and total and some diseases mortality among Korean adults. Methods: Patients included 16,257 subjects of the Korean Multi-center Cancer Cohort who were cancer-free at baseline enrollment reported their lifestyle factors between 1993 and 2008, including the status of alcohol consumption primarily from the national death certificate. Alcohol consumption (ie, soju, beer, raw rice wine) wa
본 연구는 국내 학술지 수록 연구에 나타난 수학 학습장애의 선별 및 진단방법을 분석하여 수학 학습장애 문제 해결을 위한 토대를 마련하고자 하였다. 연구를 위해 국회전자도서관과 학술연구정보서비스에서 추출한 2000년에서 2010년 8월 현재까지의 논문 24편을 분석하였으며, 분석결과는 다음과 같다. 첫째, 분석대상논문의 54%가 선별과정을 보고하였으며, 선별과정을 보고한 논문의 대다수가 수학 학업성취도를 포함하는 학업성취도 준거를 제시하였다. 선별단계는 학업성취도 준거로 선발하는 1단계가 가장 많았다. 둘째, 수학 학습장애 진단과정을 보고한 논문은 23편(96%)으로, 정상지능과 수학 학업성취도준거가 가장 많이 사용되어 불일치 기준이 주로 적용되었음을 알 수 있었다. 셋째, 지능검사도구로 웩슬러 지능검사가 가장 많이 활용되었으며 수학 학업성취도 측정을 위해 기초학습기능검사 셈하기 영역이 가장 많이 사용되었다. 논의에서는 불일치 접근과 중재반응모델의 문제점을 지적하고, 수학 학습장애 문
The places in Seoul the long-resident overseas Chinese in Korea flock together to live nearby to each other today have lost their continuity in significance with “Chinatown”. Chinatowns in many world cities succeeded in their old networks notwithstanding the diversified settlement composition with the new-wave Chinese immigrants who need not be restricted to Chinatown. The situation in Korea where Chinatowns are newly ‘developed’for commercial functions seems not totally different on surface, bu
OBJECTIVES: In April 2000, a series of wildfires occurred simultaneously in five adjacent small cities located on the eastern coast of Korea. These wildfires burned approximately 23,794 hectares of forestland over several days. We investigated the effects of prenatal exposure to the by-products generated by wildfire disasters on birth weight. METHODS: Birth weight data were obtained for 1999-2001 from the birth registration database of the Korean National Statistical Office and matched with the
Attention to academic assessment for students with disabilities is currently increasing. Recently, the Korean Ministry of Education, Science and Technology announced the Third Five-Year Plan for the Special Education Reform including academic assessment for students with disabilities and testing accommodations. This paper reviews and discusses the nature and historical context of alternate assessments in the U. S.. Especially, this paper highlights the characteristics and issues of alternate ass
Candida antarctica lipase B (CalB) is an industrially versatile enzyme, especially for biodiesel production and organic synthesis. Recombinant expression using the E. coli system has advantages, such as lower costs, easier handling, and higher number of clones that can be screened daily compared to expression using higher organism. But the expression of CalB in E. coli is not feasible because insoluble aggregates are formed and proteolytic degradation is known to occur during expression. In this
본 연구는 근대 국민국가 형성 과정에서 국민을 형성하고 결속하는 기능을 하는 것으로 논의되어 온 국민교육 혹은 민족교육이, 디아스포라 상황에서도 비슷한 방식으로 상상되고 전개되는지를 현대 한국의 중국인 디아스포라 인구가 행해 온 유례없이 집중적인 민족교육 실천을 통해 점검하고자 한 민족지적 사례 연구이다. 한국 화교는 이민 3~4세대 사회로서는 이례적으로 대다수가 여전히 정착지인 한국의 국적이 아닌 대만의 국적을 가지고 있으며, 또한 대다수의 화교 아이들이 정규 중국인 학교에 다니고 있다. 이는 종래 민족교육과 국민 형성 간 인과관계를 확신하는 주장을 뒷받침하는 듯하지만, 필자는 한화를 둘러싼 독특한 역사적∙사회적 맥락과 사회정치적 변화가 법적∙혈연적∙문화적 연대와 교육에 미치는 영향에 주목하여, 민족교육이라는 원래의 기획이 달리 수용되고 디아스포라 상황에서 새롭게 전략화되며 한화를 특징짓는 영역이 됨을 분석하였다. 현재 한화가 민족학교를 선택하는 것은 전적으로 교육적인 이유나 과거
Research Areas
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