Eun-Kyung Park

In this study, the antiinflammatory activities of ginsenoside Rb1, which is a main constituent of the root of Panax ginseng (Araliaceae), and of its metabolite compound K, as produced by human intestinal bacteria, on lipopolysaccharide (LPS)-induced RAW264.7 cells were investigated. Compound K potently inhibited the production of NO and prostaglandin E2 in LPS-induced RAW 264.7 cells, with IC(50) values of 0.012 and 0.004 mM, respectively. Compound K also reduced the expression levels of the ind

The authors studied to demonstrate the efficacy of custom-made three-dimensional (3D)-printed titanium implants for reconstructing skull defects. From 2013 to 2015, 21 patients (8-62 years old, mean = 28.6-year old; 11 females and 10 males) with skull defects were treated. Total disease duration ranged from 6 to 168 months (mean = 33.6 months). The size of skull defects ranged from 84 × 104 to 154 × 193 mm. Custom-made implants were manufactured by Medyssey Co, Ltd (Jecheon, South Korea) using 3

The antiallergic activities of ginsenosides, which were isolated from acid-treated ginseng (Panax ginseng, Araliaceae), and their metabolites by human intestinal bacteria were measured. Ginsenoside Rh2, which is a main metabolite, had the most potent inhibitory activity on beta-hexosaminidase release from RBL-2H3 cells and in the passive cutaneous anaphylaxis reaction. The inhibitory activity of ginsenoside Rh2 was more potent than that of disodium cromoglycate, a commercial antiallergic drug. T

Ginseng was incubated under mildly acidic conditions and its inhibitory effect on a rat ischemia-reperfusion model was investigated. When ginseng was treated with 0.1% hydrochloric acid at 60 degrees C, its protopanaxadiol saponins were transformed to diasteromeric ginsenoside Rg3 and Delta20-ginsenoside Rg3. When the transformed ginseng extract, of which the main component was ginsenosides Rg3, was treated with human intestinal microflora, the main metabolite was ginsenoside Rh2. Orally adminis

Tectoridin isolated from the flowers of Pueraria thunbergiana (Leguminosae) are metabolized to tectorigenin by human intestinal microflora. When tectoridin was orally administered to rats, tectorigenin, but not tectoridin, was detected in urine after beta-glucuronidase hydrolysis. The main metabolite tectorigenin potently inhibited the passive cutaneous anaphylaxis reaction and inhibited in vitro the release of beta-hexosaminidase from RBL-2H3 cells induced by IgE. These results suggest that tec

Revascularization technique is a pivotal armament in managing complex aneurysms and scrupulous prior planning is essential to successful outcomes.

Endoscopic fenestration of an intrasellar arachnoid cyst is a safe and simple procedure without serious complications.

Though melatonin is known to improve ultraviolet B (UVB)-induced oxidative damage and inflammatory conditions via blockade of nuclear factor (NF)-κB, interleukin (IL)-6, there is no report on anti-wrinkle effect of melatonin to date. Hence in the present study, anti-wrinkle mechanism of melatonin was elucidated in UVB treated HaCaT keratinocytes and hairless mice. Herein melatonin protected against a radical initiator tert-Butyl hydroperoxide (t-BOOH) induced reactive oxygen species (R

Supratentorial cortical ependymoma is a rare clinical entity where ependymoma occurring in the cortex without any connection to the ventricular system since ependymoma usually arises from the lining of the ventricular system or central canal of spinal cord. There have been 14 such cases reported in the literature.We report the first case of a supratentorial extraaxial cortical anaplastic ependymoma with minimal cortical attachment in a 17-years-old girl, presented with headache and complex parti

Post-hemorrhagic hydrocephalus (PHH) in preterm infant is common, life-threatening and the main cause of bad developmental outcomes. Ventriculoperitoneal (VP) shunt is used as the ultimate treatment for PHH. Low birth weight and low gestational age are the combination of worse prognostic factors while the single most important prognostic factor of VP shunting is age. Aggressive and early intervention have better effect in intraventricular hemorrhage and intracranial pressures control. It reduces

Die vorliegende Studie geht den Formen der poetischen Tranformation des Prometheus-Mythos in der deutschen Literatur vom 18. bis 20. Jahrhundert nach. Wie verwandelt sich der Prometheus-Mythos, der „Mythos der Kultur“ schlechthin, im Fall von Goethe (›Prometheus‹), Heine (›Der Gesang der Okeaniden‹), Kafka (›Prometheus‹) und Treichel (›Prometheus‹)?Goethes Prometheus war das Kind des „Jahrhunderts der Aufklärung“. Er verkörpert den von der Obhut des Gottes befreiten, mündig gewordenen Menschen,

1. PURPOSE This research is a study on constitutional diagnosis through the external appearances, and for finding shape differences of the hand and foot according to the Sasang Constitution. 2. Method We collected 148 person who were healthy and measured length, breadth, circumference and thickness of their hands and feet with 'The Measurement of R. Martin'. We analyzed shape differences of hand and foot according to the Sasang Constitution and made a certain conclusion. 3. Results and Conclusio

YouTube, the popular UCC-based social networking platform, provides variable contents and live streaming service in many field. The purpose of this study is to investigate the relationship among the characteristics of tourism-related contents, users’ satisfaction and travel intention. Furthermore, the study also examines the differences among the variables by user's characteristics. A total of 309 users who have watched the tourism contents on YouTube within six months participated in the study.

Heines Schreiben scheint fast immer um sich selbst zu kreisen: sei es in seinen Gedichten, sei es in seinen Versepen, sei es in seiner Prosa. Die vorliegende Studie geht den Eigentümlichkeiten der ich-orientierten Schreibart Heines nach. Im Mittelpunkt der Betrachtung stehen die Reisebilder-Texte. Um gleich den Kern- und Schlusspunkt zu nennen: Die auffällige Ich-Bezogenheit in seinen Reisebildern gehört zu Heines raffiniert-artistischen Schreibstrategien, mit denen er durch vordergründige Subje