Eun, Seok Chan
Seoul National University · Medicine
About the Lab
Professor Eun, Seok Chan's research lab specializes in advanced reconstructive surgery and regenerative medicine, with a focus on innovative tissue engineering and microsurgical techniques. The lab investigates the use of autologous and allogeneic stem cells for tissue regeneration, particularly in plastic and maxillofacial reconstruction. Key research directions include the application of chondro-osseous rib grafts, lateral arm flaps, and costochondral grafts for complex craniofacial defects, as well as the development of animal models for facial composite tissue allotransplantation. The lab emphasizes functional and aesthetic outcomes in trauma, congenital, and post-surgical reconstructions.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Regenerative medicine using stem cells has progressed significantly over the last decade. Plastic surgeons historically have used tissues of human being to restore various defect sites and utilized a single cell lines for the tissue regeneration. The cell sources (autologous or allogeneic), cell types (embryonic stem cell or adult stem cell), and source of tissues (bone marrow, muscle, adipose, cartilage, or blood) are very important for stem cell-based tissue coverage. Embryonic stem cells are
Corrective rhinoplasty for functional and aesthetic recovery relies much on the use of grafts. This may be effectively accomplished with alloplastic materials; however, certain circumstances mandate the use of autologous grafts. Septal and auricular cartilages are inadequate for dorsal augmentation of the Asian nose. Here, we present our experiences with the correction of nasal deformities using chondro-osseous rib grafts, aiming at anatomic and functional reconstruction of the nose dorsum, espe
The lateral arm flap is an alternative to the conventional radial forearm flap and has been widely used due to advancements in flap characteristics. Especially, the fasciocutaneous flap has been widely used in head and neck reconstruction due to its versatile characteristics and surgical feasibility. This flap has successfully undergone several useful modifications based on various anatomical studies. Here, the authors aimed to verify the versatility and reliability of free lateral arm flap reco
The costochondral graft is adequate for the reconstruction of the fracture, easy to obtain, easily adaptable to the orbital walls, and has minimal morbidity at the donor site.
Face allotransplantation represents a novel frontier in complex human facial defect reconstruction. To develop more refined surgical techniques and yield fine results, it is first imperative to make a suitable animal model. The development of a composite facial allograft model in swine is more appealing: the facial anatomy, including facial nerve and vascular anatomy, is similar to that of humans. Two operative teams performed simultaneously, one assigned to harvest the donor and the other to pr
Facial composite tissue allograft transplantation represents a novel frontier in the reconstruction of complex human facial defects. To develop more refined surgical techniques and yield fine results, it is definite to make a suitable animal model. Rabbit is a medium-sized animal and considered to have many advantages than any other animal, but published reports are very few and contain less detailed description. We made an easy and accessible facial transplantation approach and tried to ascerta
Attempts at tongue replantation are rare, possibly because of the friable nature of the tongue vasculature. We describe the successful replantation of the tongue in a patient with schizophrenia who attempted self-mutilation. Anastomosis of the right deep lingual artery and vein was performed under microscopy. To ensure that the patient did not make another mutilation attempt, he was kept under sedation in the intensive care unit, and a Denhardt mouth gag was placed for 5 days. Currently, his pro
Hallyu, or "the Korean Wave, " is the name for the tremendous popularity of Korean popular culture that has arisen among Asian countries, including Southeast Asia, Japan, and Taiwan, and even non-Asian countries in North America, Europe, the Middle East, and South America (1). With the record-breaking ratings of the television drama What is Love All About? which was aired by the China Central Television Station in the late 90's, Korean culture has been of increasing interest. After 2000, the yea
The anterolateral thigh flap is a classic flap used for various reconstruction defects. However, the flap viability of extended large skin paddles (ie, 240 cm 2 ) was doubted by many surgeons. This study reports successful experience of reconstructing extensive soft tissue defects of lower extremity using extended large skin paddles. Twelve consecutive patients who had undergone reconstruction of defects using an extended anterolateral thigh flap were identified. Patient characteristics (age, se
Severely disfiguring facial injuries can have a devastating impact on the patient's quality of life. During the past decade, vascularized facial allotransplantation has progressed from an experimental possibility to a clinical reality in the fields of disease, trauma, and congenital malformations. This technique may now be considered a viable option for repairing complex craniofacial defects for which the results of autologous reconstruction remain suboptimal. Vascularized facial allotransplanta
BACKGROUND: The management of lower eyelid ectropion is considered a challenge. Lower eyelid ectropion is conventionally reconstructed with a full-thickness skin graft or a local flap. However, complications as scar contracture and the recurrence of ectropion frequently occur. This article describes an effective surgical technique for ectropion correction using an upper eyelid as the laterally based orbicularis oculi myocutaneous flap. METHODS: The flap was used in 7 patients who were subjected
Research Areas
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