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Go-Won No

Yonsei University · Medicine

About the Lab

Professor Go-Won No's research lab specializes in perioperative medicine, with a focus on optimizing anesthetic techniques to minimize surgical stress and organ injury. The lab investigates the impact of anesthetic agents—particularly propofol—on systemic inflammation, ischemia-reperfusion injury, and end-organ protection during major surgical procedures. Key research directions include the use of regional anesthesia (e.g., thoracic epidural anesthesia), the role of anesthetic agents in modulating cellular signaling (such as cAMP pathways), and strategies to improve airway management and oxygenation in challenging clinical scenarios. The lab also explores biomarkers and clinical outcomes related to acute kidney injury and organ dysfunction following cardiac and vascular surgery.

anesthetic agentsischemia-reperfusion injuryperioperative organ protectioncAMP signalingacute kidney injury

Research Overview

Papers
23
Total Citations
318
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2018
2019
2020
2024
2025
Citations per year (5y)
69total
20182019202020242025

Selected Papers

15
1
Article|154 citations·2012
Incidence and Risk Factors of Acute Kidney Injury After Thoracic Aortic Surgery for Acute Dissection
Go Un Roh, Jong Wha Lee, Sang Beom Nam, Jonghoon Lee, Jong-rim Choi, Yon Hee Shim
SJR Q1The Annals of Thoracic Surgery
Pulmonary and Respiratory MedicineMedicine
2
Article|34 citations·2009
Effects of Thoracic Epidural Analgesia Combined with General Anesthesia on Intraoperative Ventilation/Oxygenation and Postoperative Pulmonary Complications in Robot-Assisted Laparoscopic Radical Prostatectomy
Jeong‐Yeon Hong, Sung Jin Lee, Koon Ho Rha, Go Un Roh, So Young Kwon, Hae Keum Kil
SJR Q1Journal of EndourologyOA

TEA combined with general anesthesia improved intraoperative ventilation/oxygenation. Although clinical and radiologic pulmonary complications were not significantly influenced, TEA can be considered an option for patients with limited reserve capacity or preexisting impairments of visceral blood flow.

SurgeryMedicine
3
Article|31 citations·2019
Effects of propofol on the inflammatory response during robot-assisted laparoscopic radical prostatectomy: a prospective randomized controlled study
Go Un Roh, Young Song, Junbeom Park, Yu Min Ki, Dong Woo Han
SJR Q1Scientific ReportsOA

Abstract Robot-assisted laparoscopic radical prostatectomy (RALRP) is a minimally invasive procedure; however, some amount of surgical trauma that can trigger systemic inflammation remains. Moreover, pneumoperitoneum during RALRP induces ischemia–reperfusion injury (IRI). Propofol, an anesthetic, is known to have anti-inflammatory and antioxidant properties. In the present study, we compared the effects of propofol with those of desflurane on inflammation and IRI during RALRP via measurements of

Pulmonary and Respiratory MedicineMedicine
4
Article|26 citations·2014
Efficacy of Palonosetron Versus Ramosetron on Preventing Opioid-Based Analgesia-Related Nausea and Vomiting After Lumbar Spinal Surgery
Go Un Roh, So Young Yang, Jae‐Kwang Shim, Young Lan Kwak
SJR Q1SpineOA

1.

SurgeryMedicine
5
Article|21 citations·2019
Randomized comparison of McGrath MAC videolaryngoscope, Pentax Airway Scope, and Macintosh direct laryngoscope for nasotracheal intubation in patients with manual in-line stabilization
Go Un Roh, Hyun Jeong Kwak, Kyung Cheon Lee, Sun Young Lee, Jong Yeop Kim
SJR Q1Canadian Journal of Anesthesia/Journal canadien d anesthésieOA
Anesthesiology and Pain MedicineMedicine
6
Article|13 citations·2016
Prevalence and impact of incompetence of internal jugular valve on postoperative cognitive dysfunction in elderly patients undergoing robot-assisted laparoscopic radical prostatectomy
Go Un Roh, Won Oak Kim, Koon Ho Rha, Byung Ho Lee, Hae Won Jeong, Sungwon Na
SJR Q1Archives of Gerontology and GeriatricsOA
NeurologyMedicine
7
Article|12 citations·2020
Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study
Go Un Roh, Joon Gwon Kang, Jung Youn Han, Chul Ho Chang
SJR Q1BMC AnesthesiologyOA

Abstract Background Airway management is a part of routine anesthetic procedures; however, serious complications, including hypoxia and death, are known to occur in cases of difficult airways. Therefore, alternative techniques such as fiberoptic bronchoscope-assisted intubation (FOB intubation) should be considered, although this method requires more time and offers a limited visual field than does intubation with a direct laryngoscope. Oxygen insufflation through the working channel during FOB

Anesthesiology and Pain MedicineMedicine
8
Article|9 citations·2012
Incidence and risk factors of acute kidney injury after thoracic aortic surgery for acute dissection
Jungwoo Lee, Go Un Roh, Jae Geun Kim, Yon Hee Shim
SJR Q1European Journal of Anaesthesiology

Background and Goal of Study: Previous studies reported a high incidence of acute kidney injury (AKI) after thoracic aortic surgery in heterogeneous patient cohort, including various aortic pathologies and the use of deep hypothermic cardiac arrest. Moderate hypothermia with selective cerebral perfusion makes deep hypothermia non-essential but can make end-organ susceptible to ischemia during circulatory arrest. We investigated incidence and risk factors of AKI after graft replacement of thoraci

Cardiology and Cardiovascular MedicineMedicine
9
Article|6 citations·2010
Effects of propofol on β-adrenoceptor-mediated signal transduction in cardiac muscle; role of cAMP
Chul Ho Chang, Go Un Roh, Wyun Kon Park
SJR Q1Korean journal of anesthesiologyOA

BACKGROUND: Propofol may decrease myocardial contractility via actions on the beta-adrenoceptor-mediated signal transduction. The aim of this study was to evaluate the effect of propofol via beta-adrenoceptor-mediated signal transduction by measuring the tissue levels of cAMP (cyclic adenosine monophosphate). METHODS: The effects of propofol on beta-adrenoceptor mediated cascades were measured with cAMP concentrations, which were stimulated by agonists (l-isoproterenol, GTPgammaS, and forskolin)

Pathology and Forensic MedicineMedicine
10
Article|3 citations·2015
Effect of glucose–insulin–potassium on hyperlactataemia in patients undergoing valvular heart surgery
Go Un Roh, Jae‐Kwang Shim, Jong Wook Song, Hye Min Kang, Young Lan Kwak
SJR Q1European Journal of AnaesthesiologyOA

Clinicaltrials.gov identifier: NCT01825720.

Endocrinology, Diabetes and MetabolismMedicine
11
Article|3 citations·2015
Modelling of the Sedative Effects of Propofol in Patients undergoing Spinal Anaesthesia: A Pharmacodynamic Analysis
Go Un Roh, Youngsoon Kim, Sang Hee Ha, Kyu Hee Jeong, Sumin Choi, Dong Woo Han
SJR Q2Basic & Clinical Pharmacology & ToxicologyOA

Sedation can increase patient comfort during spinal anaesthesia. Understanding the relationship between the propofol effect-site concentration (Ce) and patient sedation level could help clinicians achieve the desired sedation level with minimal side effects. We aimed to model the relationship between the propofol Ce and adequate and deep sedation and also incorporate covariates. Thirty patients scheduled for orthopaedic surgery received spinal anaesthesia with 0.5% bupivacaine. Propofol was admi

Anesthesiology and Pain MedicineMedicine
12
Article|2 citations·2018
Discrimination ability of the endotracheal tube location using real-time palpation during intubation using an endotracheal tube with a preloaded stylet
Go Un Roh, Yun Jeong Chae, Young-Bok Lee, Wikwang Wang, Chang Ik Choi, In Kyong Yi
SJR Q1Therapeutics and Clinical Risk ManagementOA

The real-time palpation method during intubation using an ETT with a preloaded stylet is an instantly applicable technique with good discrimination ability. The addition of real-time information through this palpation method to the conventional intubation process, especially in patients with poor vocal cord visualization, would be useful to facilitate the process of safe and careful endotracheal intubation.

Anesthesiology and Pain MedicineMedicine
13
Article|2 citations·2018
Prediction of emergence agitation using withdrawal reaction following rocuronium injection in preschool-aged patients undergoing inguinal herniorrhaphy: a preliminary exploratory observational trial
Dae Hee Kim, Go Un Roh, Young Bok Lee, Chang Ik Choi, Jae Moon Lee, Yun Jeong Chae
SJR Q1Therapeutics and Clinical Risk ManagementOA

The findings of this preliminary exploratory observational study suggest that it is possible for withdrawal movement following rocuronium injection during anesthesia induction to reflect pain sensitivity of pediatric patients, which in turn may be useful in identifying those at risk of severe EA on admission to the PACU among preschool children undergoing inguinal herniorrhaphy. Further studies with a larger sample size are required to validate these findings. The exact correlation between pain

Anesthesiology and Pain MedicineMedicine
14
letter|1 citations·2019
In reply: Comparing videolaryngoscope and direct laryngoscope use for nasotracheal intubation in patients with manual in-line stabilization
Go Un Roh, Jong Yeop Kim
SJR Q1Canadian Journal of Anesthesia/Journal canadien d anesthésieOA
Anesthesiology and Pain MedicineMedicine
15
Article|1 citations·2012
The effect of airway pressure change after prone positioning on intraoperative blood loss in patients undergoing spine surgery
Go Un Roh, Jae Chul Koh, Chul Ho Chang, Jong Seok Lee
SJR Q1European Journal of Anaesthesiology

Yonsei University College of Medicine, Department of Anaesthesiology and Pain Medicine, Seoul, Korea, Republic of

SurgeryMedicine

Research Areas

Anesthesiology and Pain MedicineSurgeryPulmonary and Respiratory MedicineNeurologyCardiology and Cardiovascular MedicinePathology and Forensic Medicine

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