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Gwang-Kyu Hwang

Hanyang University · Medicine

About the Lab

Professor Gwang-Kyu Hwang's research lab specializes in oral and maxillofacial regeneration, focusing on guided bone regeneration (GBR), sinus augmentation, and the development of biomaterials for alveolar bone repair. The lab investigates innovative biomaterials such as silk fibroin and preformed titanium meshes as barrier membranes, while also exploring the impact of systemic conditions—like rheumatoid arthritis—on periodontal health and treatment outcomes. A key emphasis is placed on improving clinical outcomes through advanced local anesthetic techniques and the use of autologous growth factors such as platelet-rich fibrin (PRF) in implantology and regenerative procedures.

guided bone regenerationbiomaterialssinus augmentationplatelet-rich fibrinalveolar bone regeneration

Research Overview

Papers
85
Total Citations
1,072
Papers (5y)
11
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
11total
2022
2023
2024
2025
2026
Citations per year (5y)
51total
20222023202420252026

Selected Papers

15
1
Article|84 citations·2013
The Effect of Mineral Trioxide Aggregate on Odontogenic Differentiation in Dental Pulp Stem Cells
Min‐Seock Seo, Kyung‐Gyun Hwang, Jae‐Seon Lee, Seokjoong Kim, Seung‐Ho Baek
SJR Q1Journal of Endodontics
Oral SurgeryDentistry
2
Article|68 citations·2015
Tissue-Engineered Bone With 3-Dimensionally Printed β-Tricalcium Phosphate and Polycaprolactone Scaffolds and Early Implantation: An In Vivo Pilot Study in a Porcine Mandible Model
S. Konopnicki, Basel Sharaf, Cory M. Resnick, Adam Patenaude, Tracy Pogal-Sussman, Kyung‐Gyun Hwang, Harutsugi Abukawa, Maria J. Troulis
SJR Q1Journal of Oral and Maxillofacial Surgery
Biomedical EngineeringEngineering
3
Article|62 citations·2010
Factors for Maxillary Sinus Volume and Craniofacial Anatomical Features in Adults With Chronic Rhinosinusitis
Seok Hyun Cho, Tae Heon Kim, Kyung Rae Kim, Jong‐Min Lee, Dong-Kyun Lee, Jae‐Hun Kim, Jae‐Jung Im, Chang‐Joo Park, Kyung‐Gyun Hwang
Archives of Otolaryngology - Head and Neck SurgeryOA

Regardless of CRS, maxillary sinus volume decreased with older age and increased with alveolar bone loss. Regarding craniofacial anatomical features, CRS may have an effect on malocclusion in adults.

OtorhinolaryngologyMedicine
4
Article|58 citations·2008
Postoperative Stability After Sagittal Split Ramus Osteotomies for a Mandibular Setback With Monocortical Plate Fixation or Bicortical Screw Fixation
Il-Hyuk Chung, Chung-Kyu Yoo, Eun Kyung Lee, Jong-An Ihm, Chang‐Joo Park, Ji-Sun Lim, Kyung‐Gyun Hwang
SJR Q1Journal of Oral and Maxillofacial Surgery
OrthodonticsDentistry
5
Review|50 citations·2018
Local anesthesia for mandibular third molar extraction
Chang Kim, Kyung‐Gyun Hwang, Chang‐Joo Park
Journal of Dental Anesthesia and Pain MedicineOA

Mandibular third molar extraction is commonly performed in dental clinics. However, the optimal method of anesthesia has not been established for this procedure. The conventional inferior alveolar nerve block is the most widely used method. However, its success rate is not high and it may lead to complications, such as aspiration and nerve injury. Therefore, various anesthesia methods are being investigated. Articaine has been proven to be efficacious in a number of studies and is being used wit

Oral SurgeryDentistry
6
Article|48 citations·2016
Cell attachment and proliferation of osteoblast-like MG63 cells on silk fibroin membrane for guided bone regeneration
Chae-Kyung Yoo, Jae-Yun Jeon, You-Jin Kim, Seong‐Gon Kim, Kyung‐Gyun Hwang
SJR Q2Maxillofacial Plastic and Reconstructive SurgeryOA

The aim of this study is to verify the feasibility of using silk fibroin (SF) as a potential membrane for guided bone regeneration (GBR). Various cellular responses (i.e., cell attachment, viability, and proliferation) of osteoblast-like MG63 cells cultured on an SF membrane were quantified. After culturing on an SF membrane for 1, 5, and 7 days, the attachment and surface morphology of MG63 cells were examined by optical and scanning electron microscopy (SEM), cell viability was determined usin

BiomaterialsMaterials Science
7
Article|47 citations·2014
Preliminary evaluation of a three-dimensional, customized, and preformed titanium mesh in peri-implant alveolar bone regeneration
Gyu‐Un Jung, Jae-Yun Jeon, Kyung‐Gyun Hwang, Chang‐Joo Park
SJR Q2Journal of the Korean Association of Oral and Maxillofacial SurgeonsOA

The use of preformed titanium mesh may support bone regeneration by maintaining space for new bone growth through its macro-pores. This preliminary study presents the efficacy of a preformed titanium mesh as a ready-to-use barrier membrane around peri-implant alveolar bone defect. This preformed mesh is also convenient to apply and to remove.

Oral SurgeryDentistry
8
Article|40 citations·2018
Effects of Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Response to Periodontal Treatment in Patients with Rheumatoid Arthritis
Gyu-Un Jung, Ji‐Young Han, Kyung‐Gyun Hwang, Chang‐Joo Park, Panagiota G. Stathopoulou, Joseph P. Fiorellini
SJR Q2BioMed Research InternationalOA

Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory diseases and periodontitis is known to be more common and more severe in patients with RA. Based on a paucity of studies about the relationship between common conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) and periodontitis, this prospective study aimed to evaluate the adjunctive effect of csDMARDs on response to nonsurgical periodontal treatment in patients with RA. Thirty-two patients with RA (

RheumatologyMedicine
9
Article|38 citations·2020
Radiologic comparative analysis between saline and platelet‐rich fibrin filling after hydraulic transcrestal sinus lifting without adjunctive bone graft: A randomized controlled trial
Yong‐Seok Cho, Kyung‐Gyun Hwang, Sang-Ho Jun, Marco Tallarico, Amy M. Kwon, Chang‐Joo Park
SJR Q1Clinical Oral Implants Research

OBJECTIVES: To evaluate implant survival rate, any complications, and changes in residual alveolar bone height (RABH) using saline or platelet-rich fibrin (PRF) filling after hydraulic transcrestal sinus lifting. METHODS: Dental implants were placed after hydraulic transcrestal sinus lifting and the filling of saline (20 patients) or PRF (20 patients). Outcome measurements were implant survival, any complications, and RABH changes. Cone-beam computed tomography (CBCT) scans were taken and compar

UrologyMedicine
10
Article|33 citations·2019
The preliminary study for three-dimensional alveolar bone morphologic characteristics for alveolar bone restoration
Hyun‐Jae Cho, Jae-Yun Jeon, Sungjin Ahn, Sung Won Lee, Joo-Ryun Chung, Chang‐Joo Park, Kyung‐Gyun Hwang
SJR Q2Maxillofacial Plastic and Reconstructive SurgeryOA

BACKGROUND: The concept of the ideal morphology for the alveolar bone form is an important element to reconstruct or restore the in maximizing esthetic profile and functional alveolar bone restoration. The purpose of this preliminary study is to evaluate the normal alveolar bone structure to provide the standard reference and guide template for use in diagnosing for implant placement, determining the correct amount of bone augmentation in actual clinical practice and producing prostheses based o

Oral SurgeryDentistry
11
Article|32 citations·2020
The Prevalence of Sjögren's Syndrome in Rheumatoid Arthritis Patients and Their Clinical Features
Hyoungyoung Kim, Soo‐Kyung Cho, Hye Won Kim, Jung-Yong Han, Yu-Jeong Kim, Kyung‐Gyun Hwang, Yoon‐Kyoung Sung
SJR Q2Journal of Korean Medical ScienceOA

BACKGROUND: To estimate the prevalence of Sjögren's syndrome (SS) in patients with rheumatoid arthritis (RA) and to compare the clinical features of RA patients with and without SS. METHODS: We conducted a retrospective study of RA patients who visited a rheumatology clinic in a tertiary referral hospital in Korea between May 20 and July 22, 2016. All patients fulfilled the classification criteria for RA, and the diagnosis of SS was made clinically by rheumatologists and according to the 2002 Am

PhysiologyMedicine
12
Article|23 citations·2008
Partial‐Thickness Cortical Bone Graft From the Mandibular Ramus: A Non‐Invasive Harvesting Technique
Kyung‐Gyun Hwang, Kwang‐Sup Shim, Seung‐Min Yang, Chang‐Joo Park
SJR Q1Journal of Periodontology

BACKGROUND: The conventional method of harvesting full cortical bone from the mandibular ramus was reported to have associated complications ranging from postoperative pain and swelling to impaired inferior alveolar nerve function. METHODS: A modified ramal bone harvesting technique is described in which partial cortical-type bone is harvested from the mandibular ramus and used for an autogenous bone graft. RESULTS: Partial-thickness cortical bone was harvested without paresthesia while reducing

Oral SurgeryDentistry
13
Article|18 citations·2008
Ideal implant positioning in an anterior maxillary extraction socket by creating an apico-palatal guiding slot: a technical note.
Kyung‐Gyun Hwang, Chang‐Joo Park
PubMed

In anterior maxillary extraction sockets, immediate implants are usually positioned along the palatal slope of the extraction socket. However, this positioning frequently causes unintentional slipping of dental implant toward thin labial plate, leading to its fracture or perforation. To prevent this, the present authors have created a simple apico-palatal guiding slot in the extraction socket following atraumatic extraction. Guided by this slot, sequential drilling up to implant placement can be

Oral SurgeryDentistry
14
Article|17 citations·2011
Bisphosphonate related osteonecrosis of jaw
Kyung‐Gyun Hwang
The Journal of The Korean Dental AssociationOA

Bisphosphonates are widely used in the management of osteoporosis patients. Many reports and clinical studies have published a relationship between necrotic bone lesions localized to the jaw and the use of chronic bisphosphonate therapy. This osteonecrosis named bisphosphonate-related osteonecrosis of the jaw(BRONJ). This article described the mechanism, chemical structure, indication, risk factor of the bisphosphonate.

OncologyMedicine
15
Article|12 citations·2023
Stem Cell Oriented Exosomes Regulate Cell Proliferation in Hepatoma Carcinoma
Gul Karima, Kyusoon Shin, Jaemin Jeong, Dongho Choi, Kyung‐Gyun Hwang, Jong Wook Hong
SJR Q2Biotechnology and Bioprocess Engineering
Molecular BiologyBiochemistry, Genetics and Molecular Biology

Research Areas

Oral SurgeryAnesthesiology and Pain MedicineSurgeryPhysiologyPeriodonticsBiomedical Engineering

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