Hak-Joon Kim

Korea University · Medicine

About the Lab

Professor Hak-Joon Kim's research lab specializes in molecular and translational biomedical research, focusing on tissue regeneration, particularly in tendon and bone healing. The lab investigates growth factors such as BMP-2, TGF-β, and IGF-II, and their roles in modulating signaling pathways like Src-ERK1/2 and PI3K in angiogenesis and tissue repair. Utilizing animal models and biomaterial carriers like fibrin glue, the lab explores innovative strategies to enhance healing at the bone-tendon junction and other musculoskeletal interfaces. The work also extends to clinical applications, including the evaluation of biomaterial safety and the mechanisms of soft tissue repair.

tendon healingbone-tendon junctiongrowth factorsbiomaterialssignaling pathways

Research Overview

Papers

425

Total Citations

5,080

Papers (5y)

Primary Field

Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)

50total

2021

2022

2023

2024

2025

Citations per year (5y)

380total

20212022202320242025

Selected Papers

Article|213 citations·2009

Solution Nuclear Magnetic Resonance Structure of Membrane-Integral Diacylglycerol Kinase

Wade D. Van Horn, Hak Jun Kim, Charles D. Ellis, Arina Hadziselimovic, Endah S. Sulistijo, M. Karra, Changlin Tian, Frank D. Sönnichsen, Charles R. Sanders

SJR Q1ScienceOA

Escherichia coli diacylglycerol kinase (DAGK) represents a family of integral membrane enzymes that is unrelated to all other phosphotransferases. We have determined the three-dimensional structure of the DAGK homotrimer with the use of solution nuclear magnetic resonance. The third transmembrane helix from each subunit is domain-swapped with the first and second transmembrane segments from an adjacent subunit. Each of DAGK's three active sites resembles a portico. The cornice of the portico app

Molecular BiologyBiochemistry, Genetics and Molecular Biology

Article|148 citations·2009

Recent advances in the application of solution NMR spectroscopy to multi-span integral membrane proteins

Hak Jun Kim, Stanley C. Howell, Wade D. Van Horn, Young Ho Jeon, Charles R. Sanders

SJR Q1Progress in Nuclear Magnetic Resonance SpectroscopyOA

Molecular BiologyBiochemistry, Genetics and Molecular Biology

Article|59 citations·2020

Enhanced tendon restoration effects of anti-inflammatory, lactoferrin-immobilized, heparin-polymeric nanoparticles in an Achilles tendinitis rat model

Hong Joon Choi, Somang Choi, Jae Gyoon Kim, Mi Hyun Song, Kyu-Sik Shim, Youn‐Mook Lim, Hak Jun Kim, Kyeongsoon Park, Sung Eun Kim

SJR Q1Carbohydrate Polymers

Orthopedics and Sports MedicineMedicine

Article|49 citations·2008

A numerical analysis for the cooling module related to automobile air-conditioning system

Hak Jun Kim, Charn-Jung Kim

SJR Q1Applied Thermal Engineering

Aerospace EngineeringEngineering

Article|47 citations·2016

The contribution of anterior deltoid ligament to ankle stability in isolated lateral malleolar fractures

Tae Hoon Lee, Kyu Sun Jang, Gi Won Choi, Chan Dong Jeong, Suk‐Joo Hong, Min A Yoon, Hak Jun Kim

SJR Q1Injury

Orthopedics and Sports MedicineMedicine

Article|42 citations·1999

Inhibition of immunoglobulin E production by Poncirus trifoliata fruit extract

H.M. Kim, H.M. Kim, Hak Jun Kim, Hak Jun Kim, So‐Hyun Park

SJR Q1Journal of Ethnopharmacology

PhysiologyMedicine

Article|38 citations·2019

Relationship Between Isokinetic Muscle Strength and Functional Tests in Chronic Ankle Instability

Young Hwan Park, Se Hyun Park, Soo Hyun Kim, Gi Won Choi, Hak Jun Kim

SJR Q2The Journal of Foot & Ankle Surgery

Orthopedics and Sports MedicineMedicine

Article|29 citations·2016

Comparison of clinical and radiologic outcomes between non-operative and operative treatment in 5th metatarsal base fractures (Zone 1)

Tae‐Hoon Lee, Ji Ho Lee, Suh Woo Chay, Kyu Sun Jang, Hak Jun Kim

SJR Q1Injury

Orthopedics and Sports MedicineMedicine

Article|28 citations·2017

Ideal angle of syndesmotic screw fixation: A CT-based cross-sectional image analysis study

Young Hwan Park, Wonseok Choi, Gi Won Choi, Hak Jun Kim

SJR Q1Injury

Orthopedics and Sports MedicineMedicine

Article|28 citations·2017

The predictive value of MRI in the syndesmotic instability of ankle fracture

Young Hwan Park, Min A Yoon, Wonseok Choi, Gi Won Choi, Suk‐Joo Hong, Hak Jun Kim

SJR Q2Skeletal Radiology

Orthopedics and Sports MedicineMedicine

Article|27 citations·2011

The Effect of Platelet Rich Plasma from Bone Marrow Aspirate with Added Bone Morphogenetic Protein-2 on the Achilles Tendon-Bone Junction in Rabbits

Hak Jun Kim, Hyok-Woo Nam, Chang-Yong Hur, Misu Park, Hee Seok Yang, Byung‐Soo Kim, Jung Ho Park

SJR Q1Clinics in Orthopedic SurgeryOA

Bone marrow derived PRP and BMP-2 in fibrin glue accelerated healing in a rabbit model of tendon-bone junction injury.

UrologyMedicine

Article|25 citations·2017

How early must an acute Achilles tendon rupture be repaired?

Young Hwan Park, Seong Min Jeong, Gi Won Choi, Hak Jun Kim

SJR Q1Injury

Orthopedics and Sports MedicineMedicine

Article|25 citations·2017

Risk factors and the associated cutoff values for failure of corticosteroid injection in treatment of Morton’s neuroma

Young Hwan Park, Ja Woon Lee, Gi Won Choi, Hak Jun Kim

SJR Q1International Orthopaedics

Radiology, Nuclear Medicine and ImagingMedicine

Article|24 citations·2007

The Role of Transforming Growth Factor-β and Bone Morphogenetic Protein with Fibrin Glue in Healing of Bone-Tendon Junction Injury

Hak Jun Kim, Sun‐Woong Kang, Hong-Chul Lim, Seung-Bum Han, Jae Sun Lee, Leela M. Prasad, Seok-Mann Yoon, Byung‐Soo Kim, Jung Ho Park

SJR Q2Connective Tissue Research

Bone-tendon junction injuries have poor healing potential. This study evaluated the role of TGF-beta and BMP-2 in a fibrin glue carrier in healing of injuries at bone-tendon junction. Seventy-two skeletally mature male rabbits were divided into 4 groups. The tendo-Achilles was surgically transected at its insertion and reattached with a pullout suture. Group 1 served as a control. In groups 2, 3, and 4, fibrin glue, a mixture of TGF-beta and fibrin glue, and a mixture of BMP-2 and fibrin glue we

Orthopedics and Sports MedicineMedicine

Review|23 citations·2018

Implant Arthroplasty versus Arthrodesis for the Treatment of Advanced Hallux Rigidus: A Meta-analysis of Comparative Studies

Young Hwan Park, Jae Hyun Jung, Seonghyun Kang, Gi Won Choi, Hak Jun Kim

SJR Q2The Journal of Foot & Ankle Surgery

Orthopedics and Sports MedicineMedicine

Research Areas

Orthopedics and Sports MedicineAerospace EngineeringSurgeryBiomedical EngineeringPublic Health, Environmental and Occupational HealthMolecular Biology

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