Hoyoung Bae
Seoul National University · Medicine
About the Lab
Professor Hoyoung Bae's research lab specializes in urological oncology and minimally invasive surgical techniques, with a strong focus on robotic and laparoscopic surgery for genitourinary cancers and renal diseases. The lab investigates clinical outcomes, biomarkers, and surgical innovations—particularly in prostate cancer, upper tract urothelial carcinoma, and partial nephrectomy—using advanced imaging, inflammatory markers, and robotic platforms like the da Vinci Single-Port system. Research also emphasizes patient-reported outcomes, such as post-prostatectomy incontinence, and long-term oncological and functional results in urological surgery.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
14The clinical value of sarcopenia has not been determined yet in metastatic hormone-sensitive prostate cancer (mHSPC). We retrospectively evaluated data of 70 consecutive patients with mHSPC receiving treatment with either early docetaxel (n = 42) or abiraterone acetate (n = 28) between July 2018 and April 2021. Skeletal muscle index was calculated from cross-sectional areas of skeletal muscle on baseline computed tomography (CT), defining sarcopenia as a skeletal muscle index of ≤52.4 cm2/m2. Fa
Purpose: To compare the perioperative outcomes and oncological results of open, laparoscopic, and robotic radical nephroureterectomy (RNU) in patients with upper tract urothelial carcinoma (UTUC) and to analyze trends in the utilization of RNU. Methods: From 2017 to 2020, the records of 61, 185, and 119 patients who underwent open, laparoscopic, and robotic RNU, respectively, were reviewed. Results: Baseline characteristics were not significantly different among the three groups. Robotic RNU has
Objective: To compare the surgical results of retroperitoneal (RP) robot partial nephrectomy (PNx) using either a single-port robot (SP) or a multi-port robot (MP). Materials and Methods: We retrospectively reviewed all RP robotic PNx performed at a single institution from September 2021—when the SP robot was introduced to the institution—through April 2023. In total, 125 patients underwent the surgery; 81 patients were treated with surgery using a MP robot whereas 44 patients were treated with
OBJECTIVES: Nephrolithiasis, with a prevalence of 9% and increasing worldwide, has a recurrence rate close to 50%. Urinary stones significantly impact quality of life and impose substantial economic burdens on patients and healthcare systems. Systemic inflammation is postulated as a risk factor for urinary stones. Previous studies have identified associations between inflammatory markers and kidney stones, but these often rely on patient recall, introducing potential recall bias. This study inve
PURPOSE: This study aimed to evaluate the feasibility, safety, and perioperative outcomes of the supine anterior retroperitoneal approach (SARA) using the da Vinci single-port (SP) robotic system for partial nephrectomy (PN) and retroperitoneal organ surgeries. MATERIALS AND METHODS: From December 2023 to December 2024, 35 retroperitoneal surgeries, including 25 PN and 10 other procedures (e.g., adrenalectomy, pyeloplasty, ureterectomy), were performed via SARA with the da Vinci SP system by a s
You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy IV (PD61)1 May 2024PD61-06 ANALYSIS OF BIOFEEDBACK FACTORS RELATED TO POST-PROSTATECTOMY INCONTINENCE Woocheol Kang, Hoyoung Bae, Ji Hyung Yoon, Taekmin Kwon, Sungchan Park, Kyung Hyun Moon, Sang Hyeon Cheon, and Seong Cheol Kim Woocheol KangWoocheol Kang , Hoyoung BaeHoyoung Bae , Ji Hyung YoonJi Hyung Yoon , Taekmin KwonTaekmin Kwon , Sungchan ParkSungchan Park , Kyung Hyun MoonKyung Hyun Moon , Sang Hyeon CheonSang
To evaluate the performance of ChatGPT-4o in estimating International Prostate Symptom Score (IPSS) and Overactive Bladder Symptom Score (OABSS) based on patients’ natural language descriptions and full outpatient records, compared to actual questionnaire scores. This study included 91 patients, of whom 52 completed IPSS and 77 completed OABSS. ChatGPT-4o was prompted with verbatim symptom statements and full medical records written by a urologist. Predicted scores were compared to actual scores
PURPOSE: This study aimed to investigate the relationship between truncal muscle mass, particularly the skeletal truncal muscle mass index (sTMI), and overactive bladder (OAB) symptoms in adult men, using bioelectrical impedance analysis (BIA). MATERIALS AND METHODS: We retrospectively analyzed health screening data from 5,475 men aged ≥40 years collected between 2014 and 2022. OAB was defined as an OAB Symptom Score (OABSS) ≥3 and urgency score ≥2, with moderate-to-severe OAB defined as OABSS ≥
Background: Differentiating histologic subtypes of fat-poor small renal masses using conventional imaging remains difficult due to their overlapping radiologic characteristics. We aimed to develop a machine learning-based diagnostic model using CT-derived radiomic features to classify the five most common renal tumor subtypes: clear cell RCC (ccRCC), papillary RCC (pRCC), chromophobe RCC (chRCC), angiomyolipoma (AML), and oncocytoma. Methods: A total of 499 patients with pathologically confirmed
Background: We investigated whether EphA2 inhibition can attenuate the progression of renal cell carcinoma (RCC) in an orthotopic mouse model of kidney tumor cells (Renca). Materials and Methods: 16 BALB/c mice were divided into two groups and implanted with either control or shRNA-mediated, EphA2-knockdown Renca–Luciferase cells via injection under the right renal capsule. Tumor progression was followed by in vivo bioluminescence imaging (BLI). Tumor growth was evaluated via ex vivo BLI and the
This study aimed to assess the exact location, size, and clinical significance of prostatic calcification using computed tomography (CT). We retrospectively analyzed data from 5,492 patients who underwent CT at the Department of Urology in our hospital between January 2010 and December 2020. After applying exclusion criteria (prostate cancer, post-prostatectomy, indwelling urethral catheter, severe artifacts, and software errors), 4,805 patients were included in the final analysis. Patient age,
This study aims to determine the problems involved in using a mathematical calculation to analyze the pathophysiology of nocturia using a frequency volume chart (FVC). In this retrospective study, we reviewed 253 patients who completed the FVC during ≥ 3 days for nocturia from January 2017 to February 2019. The etiology of nocturia was defined as a combination of 4 pathophysiologies, including nocturnal polyuria (NP), decreased bladder capacity (dBC), decreased nocturnal bladder capacity, and gl
Research Areas
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