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Hwaryun Lee

Ewha Womans University · Medicine

About the Lab

Professor Hwaryun Lee's research lab specializes in translational oncology, focusing on the development and evaluation of novel nanotherapeutics for advanced and metastatic cancers. The lab conducts rigorous clinical research, particularly meta-analyses of randomized controlled trials, to assess the efficacy and safety of innovative chemotherapy agents such as nanoparticle albumin-bound (nab)-paclitaxel in breast cancer treatment. A key research direction involves comparing nab-paclitaxel with conventional solvent-based taxanes to optimize first-line therapy outcomes in metastatic breast cancer. The lab also investigates the impact of changing regulatory approvals—such as the withdrawal of bevacizumab—on treatment paradigms and patient outcomes.

nanoparticle therapymetastatic breast cancerpaclitaxelmeta-analysisclinical oncology

Research Overview

Papers
1
Total Citations
56
Papers (5y)
1
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
1total
2020
Citations per year (5y)
56total
2020

Selected Papers

1
1
Review|56 citations·2020
Efficacy and safety of nanoparticle-albumin-bound paclitaxel compared with solvent-based taxanes for metastatic breast cancer: A meta-analysis
Hwaryeon Lee, Sohyun Park, Ji Eun Kang, Hee Min Lee, Sunah Kim, Sandy Jeong Rhie
SJR Q1Scientific ReportsOA

The curative effects of nanoparticle albumin-bound (nab)-paclitaxel in the first-line treatment of metastatic breast cancer (MBC) are still controversial, with even more after the removal of marketing approval of indication of bevacizumab. Five electronic databases and the related resources were searched for eligible randomized clinical trials (RCTs) without year and language restrictions to perform a meta-analysis. The studies were comparing the efficacy and safety between nab-paclitaxel chemot

OncologyMedicine

Research Areas

Oncology

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