Hye-Jung Yoo
Korea University · Medicine
About the Lab
Professor Hye-Jung Yoo's research lab specializes in biomedical engineering and nanotechnology, focusing on innovative solutions for chronic disease management, vision restoration, and targeted drug delivery. The lab develops smart healthcare systems using mobile technology and wearable sensors, such as the Ubiquitous Chronic Disease Care (UCDC) system, and explores advanced materials like silicon nanowires for retinal prosthetics. It also investigates biodegradable microcarriers and flagellated bacteria for precise, localized drug delivery, alongside durable 3D microelectrodes for long-term neural interfacing. The lab’s interdisciplinary approach bridges engineering, medicine, and materials science to address critical challenges in healthcare.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15AIMS: The rapidly increasing prevalence of chronic diseases is an important challenge to healthcare systems worldwide. To improve the quality and efficiency of chronic disease care, we investigated the effectiveness and applicability of the Ubiquitous Chronic Disease Care (UCDC) system using cellular phones and the internet for overweight patients with both Type 2 diabetes and hypertension. METHODS: We conducted a randomized, controlled clinical trial over 3 months that included 123 patients at
In this paper, a novel silicon nanowire photodetector on a flexible substrate is presented for replacing the function of photoreceptors in the retina to restore vision for the blind. An extremely high surface-to-volume-ratio characteristic of nanowire is capable of developing highly-sensitive photonic sensors. Therefore, a nanowire photodetector can be used as a stand-alone visual perception device without an external camera. The nanowire photodetector is first fabricated on a rigid substrate, a
OBJECTIVE: Study aims include determination of nationwide structural characteristics of radiation oncology facilities, types of radiation therapy equipment, availability of human resources and trends and comparisons with previous surveys. METHODS: An annual nationwide survey was conducted to collect the statistics of infrastructure since 1997. All requested questionnaires have been identical for 10 years. The questionnaires included status on basic radiation therapy facilities, human resources a
Detectors on the “Universitetsky‐Tatiana” satellite measured a smoothly varying intensity of UV radiation from the night‐time atmosphere in the nadir direction and the intensity of the energetic electron flux at the orbit. At high latitudes the UV intensity in the auroral oval is interpreted as being due to electrons penetrating into the atmosphere. At middle latitudes the UV intensity is an order of magnitude less and more data are needed to reveal the origin of this radiation. Millisecond flas
This paper presents a biodegradable polymer droplet for efficient drug delivery using flagellated bacteria. The biodegradability and the localized delivery are the most important features for determining the efficiency of drug delivery. The proposed droplet is made of poly (DL-lactic-co-glycolic acid) for the biodegradability. It is fabricated using a microfluidic device which has a Y-junction microchannel. The fabricated biodegradable droplet has diameter in the range between 20 μm and 30 μm. T
In this paper, the mechanical and electrical characteristics of 3D microelectrode are presented to provide the long-term stability of the implanted microelectrode. As the dimensions of the microelectrode become smaller, the microelectrode can be easily damaged by mechanical pressure and over-injected electric charge. In order to avoid these destructions, allowable mechanical and electrical stress should be determined. Experiments for durability evaluation are set up and performed to measure the
Drug delivery system (DDS) is concerned with targeting drugs to specific cells. To achieve bioavailability various biodegradable polymers are commonly utilized as particulate drug carriers. Common methods of fabricating biodegradable polymeric microdevices include various replication techniques, laser micromachining, and microfluidic fabrication methods. This paper reviews state-of-the-art nano and microfabrication techniques used for DDS, and presents a novel method using x-ray synchrotron for
Ketamine has demonstrated early promise for treating substance use disorder (SUD). Despite the emerging evidence for ketamine-based approaches for SUD, little has been published on the integration of ketamine-assisted psychotherapy (KAP) with existing pharmacologic, psychosocial, and peer-support approaches to treatment and recovery, including 12-step programs. Here, we present the case of a 28-year-old female treated for alcohol and opioid use disorder. We executed an inter-clinic, collaborativ
Research Areas
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