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Hye-Won Heo

Yonsei University · Medicine

About the Lab

Professor Hye-Won Heo's research lab specializes in clinical anatomy and minimally invasive aesthetic procedures, with a focus on improving safety and precision in facial rejuvenation techniques. The lab investigates detailed neuromuscular anatomy to optimize botulinum toxin and hyaluronic acid filler injections, particularly in the facial muscles and deep facial compartments. Research also extends to obstetrical and fetal imaging, assessing anatomical parameters in early pregnancy and evaluating surgical outcomes in obese patients undergoing pelvic floor surgery.

facial anatomybotulinum toxin injectionhyaluronic acid fillerfetal imagingsurgical outcomes

Research Overview

Papers
16
Total Citations
174
Papers (5y)
7
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
7total
2021
2022
2023
2024
2025
Citations per year (5y)
125total
20212022202320242025

Selected Papers

15
1
Article|61 citations·2022
Guidelines for Botulinum Neurotoxin Injection for Facial Contouring
Kyu‐Ho Yi, Hyung‐Jin Lee, Hyewon Hur, Kyle K. Seo, Hee‐Jin Kim
SJR Q1Plastic & Reconstructive SurgeryOA

SUMMARY: The hypertrophied temporalis and masseter muscles give a muscular shaped and bulky contour to the face. Botulinum neurotoxin injection methods are commonly used for facial contouring; however, adverse effects have been reported owing to a lack of delicate anatomical information. The anatomical considerations when injecting botulinum neurotoxin into the temporalis and masseter muscles were reviewed in the present study. Current knowledge on the localization of the botulinum neurotoxin in

NeurologyMedicine
2
Article|33 citations·2022
Hyaluronic acid filler injection for deep nasolabial folds: A novel intraoral approach
Kyu‐Ho Yi, Jong‐Jin Lee, Hyewon Hur, Hyungkyu Bae, Hee‐Jin Kim
SJR Q1Clinical AnatomyOA

Hyaluronic acid filler injection is a minimally invasive procedure for facial rejuvenation that involves injecting filling materials to correct the volume or augment specific areas in the face. Deep nasolabial folds are a common concern in aging people. The simplest way to correct a deep nasolabial fold to rejuvenate the face is to inject Ristow's space with hyaluronic acid fillers. However, conventional injection methods, such as percutaneous injections using a needle, can cause severe complica

DermatologyMedicine
3
Article|26 citations·2009
Perioperative and long‐term complications among obese women undergoing vaginal surgery
Ka‐Hyun Nam, Myung Jae Jeon, Hyewon Hur, Sei‐Kwang Kim, Sang Wook Bai
SJR Q1International Journal of Gynecology & ObstetricsOA

OBJECTIVE: To determine whether obesity influenced the risk of perioperative and long-term complications in patients undergoing vaginal surgery. METHODS: Women diagnosed with pelvic organ prolapse who underwent vaginal surgery between March 1999 and May 2007 were classified into 3 groups: normal weight (body mass index [BMI, calculated as weight in kilograms divided by the square of height in meters] 18.5-23.0); overweight (BMI 23.0-27.5); and obese (BMI >or=27.5). Complications were subdivided

RheumatologyMedicine
4
Article|21 citations·2023
Distribution of the intramuscular innervation of the triceps brachii: Clinical importance in the treatment of spasticity with botulinum neurotoxin
Kyu‐Ho Yi, Ji‐Hyun Lee, Hyewon Hur, Hyung‐Jin Lee, You‐Jin Choi, Hee‐Jin Kim
SJR Q1Clinical AnatomyOA

This study aimed to identify ideal sites for botulinum toxin injection by analyzing the intramuscular nerve patterns of the triceps brachii muscles. A modified Sihler's method was applied to the triceps brachii muscle (15 specimens), with long, medial, and lateral heads. The intramuscular arborization areas of the long, medial, and lateral heads of the triceps brachii muscle were measured as a percentage of the total distance from the midpoint of the olecranon (0%) to the anteroinferior point of

NeurologyMedicine
5
Article|14 citations·2015
Feasibility of three-dimensional reconstruction and automated measurement of fetal long bones using 5D Long Bone
Hyewon Hur, Young Han Kim, Hee Young Cho, Yong Won Park, Hye‐Sung Won, Mi‐Young Lee, Bo Hyon Yun, Kwang Hee Lee, Sung Yoon Kim, Junsang Yoo, Ja‐Young Kwon
SJR Q2Obstetrics & Gynecology ScienceOA

5D LB is reproducible and comparable with conventional 2D and 3D ultrasound techniques for fetal long bone measurement.

Pediatrics, Perinatology and Child HealthMedicine
6
Article|8 citations·2021
Anatomical consideration of deep calf veins: application to catheter-directed thrombolysis
Kyu‐Ho Yi, Jong-Jin Lee, Hyewon Hur, Hee‐Jin Kim
SJR Q2Surgical and Radiologic AnatomyOA
Internal MedicineMedicine
7
Article|3 citations·2009
512: Low maternal pre-pregnancy body mass index and mid-trimester weight gain: risk of preterm birth
Hyewon Hur, Maria Lee, Ja‐Young Kwon, Yong-Won Park, Young Han Kim
SJR Q1American Journal of Obstetrics and Gynecology
Obstetrics and GynecologyMedicine
8
Article|3 citations·2009
OC04.03: Frontomaxillary facial angle measurement may not be a useful early screening marker in Korean population
Joon Ho Kwon, Ga‐Hyun Son, Hyunmin Choi, Hyewon Hur, Y. Kim, Yongjung Park
SJR Q1Ultrasound in Obstetrics and GynecologyOA

To evaluate the distribution of fetal frontomaxillary facial (FMF) angle at in normal Korean population at 11 + 0 to 13 + 6 weeks gestation. Three-dimensional (3D) volumes of the fetal head were obtained from low risk singleton pregnancies at 11 + 0 to 13 + 6 weeks who consented to this prospective study. Only cases with either a normal karyotype confirmed on amniocentesis or delivered a normal live infant were considered eligible for analysis. Those with multiple pregnancies, fetal anomaly conf

Pediatrics, Perinatology and Child HealthMedicine
9
Article|2 citations·2006
로봇 복강경하 전자궁절제술: 한국최초 임상보고
김영태, 김상운, 윤보성, 남은지, 허혜원, 김성훈, 김재훈, 김재욱

=다빈치수술로봇시스템이 소개되어 전세계적으로 활발하게 외과분야에 적용이 되고 있다. 이러한 로봇수술시스템은 개발초기에 개심수술을 효율적으로 하기 위해 개발되었으나 다양한 장점으로 말미암아 외과, 비뇨기과, 산부인과, 흉부외과, 이비인후과 등에서 폭넓게 이용이 되고 있다. 더구나 부인과영역에서도 이에 대한 관심이 폭발적으로 증폭되면서 많은 부인과수술이 선진외국에서는 이루어지고 있으나 아직 국내에서는 자궁절제술을 다빈치로봇수술을 통해 진행된 경우가 전무한 상태이다. 이에 자궁경부상피내암환자를 대상으로 하여 국내에서 최초로 이루어진 로봇복강경하 전자궁절제술의 임상경험을 보고한다.

10
Article|2 citations·2025
Maternal Exposure to Diesel Exhaust Particles (DEPs) During Pregnancy and Adverse Pregnancy Outcomes: Focusing on the Effect of Particulate Matter on Trophoblast, Epithelial-Mesenchymal Transition
Hyewon Hur, Hayan Kwon, Yun Ji Jung, Euna Choi, Joonggyeong Shin, Subin Jo, Ye-Ji Lee, Min‐A Kim, Yong‐Sun Maeng, Ja‐Young Kwon
SJR Q1CellsOA

During pregnancy, exposure to fine particulate matter (PM2.5), particularly diesel exhaust particles (DEPs), elevates the risk of placental dysfunction-related pregnancy complications; however, the underlying cellular mechanisms have yet to be fully elucidated. The objective of this study was to assess the effects of PM2.5 exposure on trophoblast functions and their interaction with endometrial stromal cells. We utilized a three-dimensional (3D) model in which human first-trimester trophoblasts

Health, Toxicology and MutagenesisEnvironmental Science
11
Article|1 citations·2009
OP11.03: Prediction of preeclampsia by second trimester serum screening and uterine artery Doppler velocimetry
Ga‐Hyun Son, Chin Hong Lim, Hyewon Hur, Song I Jeon, Ja‐Young Kwon, Y. Kim, Yongjung Park
SJR Q1Ultrasound in Obstetrics and GynecologyOA

To determine the performance of screening for preeclampsia by combining second trimester maternal serum screening and uterine artery Doppler ultrasound. A total of 876 women underwent both maternal serum screening (using α-fetoprotein (AFP), uE3, and human chorionic gonadotropin (hCG)), measurement of uric acid, and second trimester uterine artery Doppler ultrasound. The sensitivity, specificity and predictive value of different combinations of tests were compared. Of 876 pregnancies originally

Obstetrics and GynecologyMedicine
12
Article|0 citations·2015
Feasibility of three-dimensional reconstruction and automated measurement of fetal long bones using 5D Long Bone
Hyewon Hur, Young Han Kim, Hee Young Cho, Yong Won Park, Hye-Sung Won, Mi‐Young Lee, Bo Hyon Yun, Kwang Hee Lee, Sung Yoon Kim, Junsang Yoo, Ja-Young Kwon

Objective To evaluate the feasibility of five-dimensional Long Bone (5D LB), a new technique that automatically archives, reconstructs images, and measures lengths of fetal long bones, to assess whether the direction of volume sweep influences fetal long bone measurements in three-dimensional (3D) ultrasound and 5D LB, and to compare measurements of fetal long bone lengths obtained with 5D LB and those obtained with conventional two-dimensional (2D) and manual 3D techniques. Methods This prospec

Pediatrics, Perinatology and Child HealthMedicine
13
Article|0 citations·2024
스티커로 만든 근육층 실습 교재
허혜원, 허미선, 김혜진, 김희진, 윤관현

근육의 해부학적 구조는 복잡하고 세밀하게 얽혀 있어, 이를 이해하기 위한 교육 자료는 일러스트레이션, 3차원 모델, 온라인 콘텐츠 등 다양한 형태로 제공되고 있다. 기존 교육 자료들은 정보 전달에 중점을 두고 있으나, 학습자가 근육의 층별 구조를 직관적으로 이해하고 기억하는 데는 한계가 있다. 본 연구는 인체 근육의 위치와 입체적 구조를 효과적으로 이해할 수 있도록 지원하기 위해 재접착이 가능한 스티커를 활용한 체험형 교육 자료를 개발하는 것을 목표로 하였다. 개발된 교재는 A2 크기의 양면 뼈대 일러스트레이션 스티커 배경 1장과 A4 크기의 앞면 및 뒷면 근육 스티커 각 7장, 총 15장으로 구성되어 있다. 근육 일러스트레이션은 앞면 62개, 뒷면 65개를 포함하여 총 127개의 근육을 표현하고 있으며, 학습자는 제공된 알파벳 순서대로 근육 스티커를 뼈대에 맞는 위치에 부착하면서 학습을 진행한다. 교재에 적용된 근육의 개수가 많고 스티커의 형태가 정교하여 성인 이상의 학습자에게 적

14
Article|0 citations·2011
236: Microarray analysis of the gene expression profiling in the cytotrophoblasts on nicotine exposure
Hee Young Cho, Hyewon Hur, Ga Hyun Son, Hayan Kwon, Yong Won Park, Young Han Kim, Ja‐Young Kwon
SJR Q1American Journal of Obstetrics and Gynecology
Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
Article|0 citations·2021
Anatomic Description of the Infraorbital Soft Tissues by Three-dimensional Scanning System
Alonso Andrés Hormazábal Peralta, 최유진, 허혜원, 허경석, 김희진

Purpose: For minimally invasive procedures, three-dimensional (3D) anatomical knowledge of the structures of the face is essential. This study aimed to describe the thickness of the skin and subcutaneous tissue and depths of the facial muscles located in the infraorbital region using a 3D scanner to provide critical clinical anatomical guidelines for improving minimally invasive cosmetic procedures. Materials and Methods: The 3D scanning images of 38 Korean cadavers (22 males and 16 females; age

Research Areas

Pediatrics, Perinatology and Child HealthNeurologyObstetrics and GynecologyDermatologyRheumatologyInternal Medicine

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