Hyohyun Ahn
Korea University · Medicine
About the Lab
Professor Hyohyun Ahn's research lab specializes in clinical and translational studies focusing on microcirculation, particularly intestinal and gastric blood flow regulation using laser Doppler flowmetry. The lab investigates the hemodynamic effects of anesthetic and analgesic agents on postoperative recovery, with a strong emphasis on optimizing gastrointestinal motility and perfusion. Additional research directions include dermatological applications of chemical peels and laser therapies for skin conditions prevalent in patients with skin of color, such as acne and post-inflammatory hyperpigmentation. The lab integrates advanced optical monitoring techniques with clinical outcomes to improve surgical and aesthetic patient care.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15The effect of postoperative epidural bupivacaine on intestinal motility was studied by measuring the transit time of barium contrast through the intestines in 16 patients after resection of the left colon and/or rectum. Fourteen patients served as controls and received postoperative injections of pentazocine. Mean transit time through the intestinal tract was 35 h in the epidural group and 150 h in the control group, a difference that is significant at the 0.1 per cent level. The average time be
Blood flow in the small intestine was assessed in 48 patients by laser Doppler flowmetry. Mucosal and serosal flowmeter signals were compared during 'resting' conditions, vascular occlusion, and reactive hyperemia. Serosal flowmeter recordings were compared with the total blood flow of a bowel segment as measured by venous collection. The magnitudes of the mucosal (n = 49) and serosal (n = 49) flowmeter signals were comparable throughout the whole range of flowmeter signals (r = 0.97; p less tha
BACKGROUND: Patients with skin of color demand treatment modality suitable for their skin. Salicylic acid peel has effectiveness for both of acne and postinflammatory hyperpigmentation that are common in patients with skin of color. OBJECTIVE: To assess the whitening effect of salicylic acid peels in Asian patients with acne objectively by the colorimetric method. METHODS: Twenty-four healthy adult patients with acne participated voluntarily in the study. Any other systemic and topical acne trea
Colonic blood flow was measured with laser Doppler flowmetry during operation in 62 patients and during coloscopy in 15 patients. In 18 subjects mucosal and serosal laser Doppler signals were compared during 'resting' conditions, vascular occlusion, and reactive hyperemia. The mucosal (n = 36) and serosal (n = 36) flowmeter signals were of the same order of magnitude throughout the whole range of flowmeter signals (r = 0.96; p less than 0.001). In eight subjects total venous outflow from a colon
A long-pulsed alexandrite laser without cryogen spray cooling is an effective and safe alternative in the treatment of BN.
The use of laser Doppler flowmetry (LDF) to measure gastric blood flow was evaluated in the cat and man. The reproducibility of laser Doppler flowmetry recordings was studied in the feline stomach. In five cats flowmeter signals and venous outflow of the stomach were simultaneously recorded. The flowmeter recordings were made during operation and gastroscopy in 140 patients by means of two different (PF1-4-kHz and PF2-12-kHz) laser Doppler systems. The flowmeter recordings were highly reproducib
Abstract Background Proper assessment of dermal collagen fibers by dermatologists and researchers is essential. Histologic evaluation methods have limitations. We present a simple method for measurement of collagen fibers in human skin using Masson's trichrome staining. Materials and Methods Normal skin specimens from a cadaver were processed with Masson's trichrome, which can effectively stain collagen fibers blue with aniline dye. Optical photomicrographs of these slides were analyzed using Im
BACKGROUND: Quantitative and objective investigations of parallel-polarized light (PPL) photography for dermatologic purposes are scarce. OBJECTIVE: To determine the significance of quantitative analysis of PPL photography to develop objective measurement methods of skin surface characteristics. METHOD: For PPL photography, a digital camera, a light-emitting diode illuminator, and polarizing filters were arranged and kept constant. We analyzed the PPL photography images of the glabella, the medi
BACKGROUND Patients with skin of color demand treatment modality suitable for their skin. Salicylic acid peel has effectiveness for both of acne and postinflammatory hyperpigmentation that are common in patients with skin of color. OBJECTIVE To assess the whitening effect of salicylic acid peels in Asian patients with acne objectively by the colorimetric method. METHODS Twenty-four healthy adult patients with acne participated voluntarily in the study. Any other systemic and topical acne treatme
BACKGROUND/PURPOSE: Although digital cameras have powerful macrocapabilities, flash macrophotographs are often unsatisfactory. The aim of this study was to develop a light-emitting diode (LED) illuminator for macro digital photography that allows colorimetric investigations of the skin. METHODS: We devised an LED illuminator suitable for acquiring super-macro digital images of the skin. Reference CIELAB color chart values were compared statistically with computed values from digital images in or
The use of videoconferencing as a teaching modality in dermatology is not widespread. The objectives of this study were to introduce the videoconferencing format to dermatology journal clubs and to determine its effects on the training and satisfaction of house officers (residents). Ten dermatology house officers participated in this study. They were being trained at three university hospitals in rotation. A videoconferencing facility maintained by the hospitals for remote conferencing was used.
Local blood flow changes in association with proximal gastric vagotomy were studied with laser Doppler flowmetry in 10 patients. After the vagotomy a significant decrease in blood flow amounting to 57 +/- 21% (range, 18-87%; p less than 0.001) was observed within the dissected area along the lesser curvature. In three patients, the flowmeter recordings suggested localized areas with very poor perfusion. The blood flow was restored to preoperative control values within 3-4 weeks after the operati
BACKGROUND/PURPOSE: The fluorescence findings of several dermatological diseases, such as erythrasma, tinea versicolor, and acne are helpful for diagnosis and follow-up. However, many experience difficulty taking photographic images of fluorescence. The aim of this study was to develop a 405 nm light-emitting diode (LED) system for fluorescence digital photography of acne and to determine whether such a diode can be used to evaluate acne. METHODS: Eight healthy acne patients were compared with c
Skin biopsy for AK diagnosis is usually performed on only a limited part of the whole lesion. Therefore, a clinical diagnosis is important. According to a study, there is no significant correlation between histopathological and clinical classification system. We examined the correlation between microscopic information and dermoscopic findings to deduce if dermoscopic information reflects histopathologic grade severity. Forty seven patients with histologically confirmed AK were enrolled and posit
Research Areas
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