Hyoseon Jang
Hanyang University · Medicine
About the Lab
Professor Hyoseon Jang's research lab focuses on respiratory and critical care medicine, with a strong emphasis on interstitial lung diseases, post-tuberculous complications, and thoracic vascular disorders. The lab investigates the clinical outcomes, risk factors, and long-term impacts of conditions such as bronchiectasis, primary spontaneous pneumothorax, and thoracic aortic dissection, particularly in young and preterm populations. Using advanced imaging techniques like high-resolution computed tomography, the lab explores the role of structural lung abnormalities—such as blebs and bullae—in disease progression and recurrence. Their work also evaluates the feasibility and outcomes of early surgical interventions in critical neonatal and adult patients.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Subjects with bronchiectasis suffered from more respiratory symptoms with limited physical activity and poorer quality of life than the general population. Factors independently associated with bronchiectasis were lower family income and comorbid pulmonary conditions, such as previous pulmonary TB, asthma, and airflow limitation.
BACKGROUND: The aim of this study was to determine the feasibility and outcomes of early surgical ligation in preterm neonates with hemodynamically significant patent ductus arteriosus (HSPDA) and to investigate predictors for surgical treatment after unsuccessful medical management. METHODS: Medical records from the neonatal intensive care unit of Hanyang University Seoul Hospital from January 2010 to December 2018 were retrospectively reviewed. 233 preterm neonates weighing less than 1500g wit
The incidence of thoracic AD has gradually increased in Korea. The in-hospital mortality in the TASR subgroup decreased over the decade, although the overall mortality of AD patients did not change.
BACKGROUND: The relationship between the size of bullae and pneumothorax recurrence is controversial. The aim of this study was to retrospectively evaluate the role of blebs or bullae in predicting ipsilateral recurrence in young patients experiencing their first episode of primary spontaneous pneumothorax (PSP) who underwent conservative treatment. METHODS: A total of 299 cases of first-episode PSP were analyzed. The status of blebs or bullae was reviewed on high-resolution computed tomography
OBJECTIVES: This retrospective cohort study aimed to analyse the impact of asymptomatic blebs/bullae on the occurrence of primary spontaneous pneumothorax (PSP) by monitoring the natural course of contralateral blebs/bullae in patients with ipsilateral pneumothorax. METHODS: From January 2003 to December 2017, 1055 patients [age 19.6 ± 3.98 years (mean ± standard deviation), 953 men] experiencing the first episode of unilateral PSP were enrolled in this study, excluding patients aged 30 years or
Post-TB subjects with bronchiectasis had more cough and physical activity limitations and lower health-related QoL than those without bronchiectasis.
Background: Neuron-specific enolase (NSE) has traditionally been used as a biomarker to predict neurologic outcomes after cardiac arrest. This study aimed to evaluate the utility of NSE in predicting neurologic outcomes in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR). Methods: This observational cohort study included 47 consecutive adult ECPR patients (median age, 59.0 years; 74.5% males) treated between January 2018 and December 2021 at a tertiary extracorporeal life
The prognosis of anaplastic thyroid carcinoma (ATC) is very poor. In most patients, ATC presents with cervical lymph node metastasis, and more than 40% of patients have distant metastasis at the time of diagnosis. Lenvatinib, a multi-targeted tyrosine kinase inhibitor, is a novel drug that has antitumor effects on radioactive iodine-refractory papillary cancer and anaplastic cancer. The development of bilateral pneumothorax during targeted therapy is very rare in patients with thyroid cancer. We
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Background: Extracorporeal cardiopulmonary resuscitation (ECPR) has the potential to improve neurological outcomes in patients with refractory out-of-hospital cardiac arrest (OHCA), offering an alternative to conventional cardiopulmonary resuscitation (CCPR). However, its effectiveness in OHCA remains controversial despite advancements in resuscitation techniques. Methods: This retrospective single-center study compared neurological outcomes and 30-day survival between ECPR and CCPR patients fro
Abstract Background : The aim of this study was to determine the feasibility and outcomes of early surgical ligation in preterm neonates with hemodynamically significant patent ductus arteriosus (HSPDA) and to investigate predictors for surgical treatment after unsuccessful medical management. Methods : Medical records from the neonatal intensive care unit of Hanyang University Seoul Hospital from January 2010 to December 2018 were retrospectively reviewed. 233 preterm neonates weighing less tha
Background: Vasoconstrictor-induced reduction in arterial graft diameter can cause significant flow deprivation. The aim of this study was to evaluate the effect of vasodilator pretreatment on vasoconstrictor-induced blood vessel spasm in vitro. Material and Method: Rabbit brachial arteries (BA) and celiac arteries (CA) were cut into rings (3∼4 mm) and suspended with a force displacement transducer (TSD 125CⓇ, Biopac Inc. USA) in a tissue bath filled with 5 mL modified Krebs solution bubbled wit
Research Areas
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