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Hyun-jong Kim

Yonsei University · Medicine

About the Lab

Professor Hyun-jong Kim's research lab specializes in hepatobiliary and pancreatic surgery, with a strong focus on surgical oncology, particularly in hepatocellular carcinoma (HCC) and rare pancreatic malignancies. The lab investigates minimally invasive surgical techniques, such as laparoscopic liver resection, and evaluates treatment outcomes, including survival, recurrence, and prognostic factors. It also explores molecular and pathological predictors of malignancy in complex pancreatic neoplasms like branch-duct intraductal papillary mucinous neoplasms (Br-IPMN) and colorectal cancer, with an emphasis on telomere biology and tumor progression. The lab aims to improve patient stratification and treatment selection through clinical, pathological, and molecular research.

hepatocellular carcinomapancreatic neoplasmsminimally invasive surgerytelomere biologysurgical oncology

Research Overview

Papers
72
Total Citations
748
Papers (5y)
19
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
19total
2014
2015
2016
2018
2019
Citations per year (5y)
290total
20142015201620182019

Selected Papers

15
1
Article|115 citations·2005
Multicenter Analysis of Clinicopathologic Features of Intraductal Papillary Mucinous Tumor of the Pancreas: Is It Possible to Predict the Malignancy Before Surgery?
Jin‐Young Jang, Sun‐Whe Kim, Young Joon Ahn, Yoo‐Seok Yoon, Min Gew Choi, Kuhn Uk Lee, Joon Koo Han, Woo Ho Kim, Young Ju Lee, Song Chul Kim, Duck Jong Han, Yong Il Kim
SJR Q1Annals of Surgical OncologyOA
OncologyMedicine
2
Article|82 citations·2011
Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection
Hohyun Kim, Eun Kyu Park, Jin Shick Seoung, Young Hoe Hur, Yang Seok Koh, Jung Chul Kim, Chol Kyoon Cho, Hyun Jong Kim
Journal of the Korean Surgical SocietyOA

Laparoscopic liver resection for HCC is feasible and safe in selected patients and can produce good surgical results with a shorter postoperative hospital stay and similar outcomes in terms of perioperative morbidity, mortality, and disease-free survival than open resection.

HepatologyMedicine
3
Article|72 citations·2014
Surgical Strategy for T1 Gallbladder Cancer: A Nationwide Multicenter Survey in South Korea
Korean Pancreas Surgery Club, Seung Eun Lee, Jin‐Young Jang, Sun‐Whe Kim, Ho‐Seong Han, Hong‐Jin Kim, Sung‐Su Yun, Baik‐Hwan Cho, Hee Chul Yu, Woo Jung Lee, Dong Sup Yoon, Dong Wook Choi
SJR Q1Annals of Surgical Oncology
SurgeryMedicine
4
Article|64 citations·2014
Volumetric analysis and indocyanine green retention rate at 15 min as predictors of post‐hepatectomy liver failure
Hee Joon Kim, Choong Young Kim, Eun Kyu Park, Young Hoe Hur, Yang Seok Koh, Hyun Jong Kim, Chol Kyoon Cho
SJR Q1HPBOA
HepatologyMedicine
5
Article|56 citations·2014
The prognostic factors for survival after curative resection of distal cholangiocarcinoma: perineural invasion and lymphovascular invasion
Hee Joon Kim, Choong Young Kim, Young Hoe Hur, Yang Seok Koh, Jung Chul Kim, Hyun Jong Kim, Chol Kyoon Cho
SJR Q2Surgery Today
SurgeryMedicine
6
Article|46 citations·2014
A comparison between surgical resection and radiofrequency ablation in the treatment of hepatocellular carcinoma
Eun Kyu Park, Hee Joon Kim, Choong Young Kim, Young Hoe Hur, Yang Seok Koh, Jung Chul Kim, Hyun Jong Kim, Jin Woong Kim, Chol Kyoon Cho
SJR Q2Annals of Surgical Treatment and ResearchOA

HCC within Milan criteria should consider hepatectomy as the primary treatment if the patient's liver function and general conditions are good enough to undergo surgical operation. But in that RFA revealed similar overall survival to HR, RFA can be an alternative therapy for patients who are eligible for surgical resection.

HepatologyMedicine
7
Article|38 citations·2011
Determination of Malignant and Invasive Predictors in Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Suggested Scoring Formula
Dae Wook Hwang, Jin‐Young Jang, Chang-Sup Lim, Seung Eun Lee, Yoo‐Seok Yoon, Young Joon Ahn, Ho‐Seong Han, Sun‐Whe Kim, Sang Geol Kim, Young Kook Yun, Seong-Sik Han, Sang‐Jae Park
SJR Q2Journal of Korean Medical ScienceOA

Prediction of malignancy or invasiveness of branch duct type intraductal papillary mucinous neoplasm (Br-IPMN) is difficult, and proper treatment strategy has not been well established. The authors investigated the characteristics of Br-IPMN and explored its malignancy or invasiveness predicting factors to suggest a scoring formula for predicting pathologic results. From 1994 to 2008, 237 patients who were diagnosed as Br-IPMN at 11 tertiary referral centers in Korea were retrospectively reviewe

OncologyMedicine
8
Article|32 citations·2002
Telomere Length Changes in Colorectal Cancers and Polyps
Hyeong Rok Kim, Young Jin Kim, Hyun Jong Kim, Shin Kon Kim, Ji Hee Lee
SJR Q2Journal of Korean Medical ScienceOA

Telomere shortening and telomerase activation occur frequently in cases of colorectal carcinoma. In this study, we correlated the clinicopathological parameters with the telomere length in colorectal carcinomas, colonic polyps, and normal colonic tissues. We also investigated whether the telomere length changes reflect the biologic behavior of tumors and different modes of tumor development. Telomere length was determined by terminal restriction fragment Southern blot analysis in 20 invasive col

PhysiologyMedicine
9
Article|32 citations·2011
Primary leiomyosarcoma of the pancreas
Young Hoe Hur, Hohyun Kim, Eun Kyu Park, Jin Shick Seoung, Jin Woong Kim, Yong Yeon Jeong, Jae Hyuk Lee, Yang Seok Koh, Jung Chul Kim, Hyun Jong Kim, Chol Kyoon Cho
Journal of the Korean Surgical SocietyOA

Primary sarcomas of the pancreas are extremely rare, accounting for 0.1% of malignant pancreatic (non-islet) neoplasms. Pancreatic leiomyosarcoma is a highly aggressive malignancy that spreads in a similar manner to gastric leiomyosarcoma, i.e., by adjacent organ invasion, hematogenous spread, and lymph node metastasis. These tumors are large at the time of diagnosis and are usually found at an advanced stage. We report a case of a 70-year-old female with intermittent right upper quadrant abdomi

GastroenterologyMedicine
10
Article|30 citations·2013
Comparison of remnant to total functional liver volume ratio and remnant to standard liver volume ratio as a predictor of postoperative liver function after liver resection
Hee Joon Kim, Choong Young Kim, Young Hoe Hur, Yang Seok Koh, Jung Chul Kim, Chol Kyoon Cho, Hyun Jong Kim
Korean Journal of Hepato-Biliary-Pancreatic SurgeryOA

BACKGROUNDS/AIMS: The future liver remnant (FLR) is usually calculated as a ratio of the remnant liver volume (RLV) to the total functional liver volume (RLV/TFLV). In liver transplantation, it is generally accepted that the ratio of the graft volume to standard liver volume (SLV) needs to be at least 30% to 40% to fit the hepatic metabolic demands of the recipient. The aim of this study was to compare RLV/TFLV versus RLV/SLV as a predictor of postoperative liver function and liver failure. METH

HepatologyMedicine
11
Article|23 citations·2011
Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells
Young Hoe Hur, Hohyun Kim, Jin Shick Seoung, Kyoung‐Won Seo, Jin Woong Kim, Yong Yeon Jeong, Jae Hyuk Lee, Yang Seok Koh, Jung Chul Kim, Hyun Jong Kim, Chol Kyoon Cho
Journal of the Korean Surgical SocietyOA

Undifferentiated carcinoma with osteoclast-like giant cells is a rare neoplasm of the exocrine pancreas. Some similar cases have been reported, but the histogenesis of these tumors varies and is controversial. We report here on a case of undifferentiated carcinoma of the pancreas with osteoclast-like giant cells. A 77-year old woman presented with abdominal pain and anorexia. Abdominal computed tomography and magnetic resonance imaging showed an approximately 10 × 5 cm highly attenuated mass ari

OncologyMedicine
12
Article|22 citations·2011
Clinical features and surgical outcome of solid pseudopapillary tumor of the pancreas: 30 consecutive clinical cases.
Hohyun Kim, Sang Kwon Yun, Jung Chul Kim, Eun Kyu Park, Jin Shick Seoung, Young Hoe Hur, Yang Seok Koh, Chol Kyoon Cho, Sang Soo Shin, Sun Seog Kweon, Hyung-Seok Kim, Hyun Jong Kim
PubMed

BACKGROUND/AIM: This study examined the clinical characteristics and surgical outcomes of solid pseudopapillary tumors of the pancreas (SPT). METHODOLOGY: Cases of SPT encountered in our hospital between January 1994 and December 2009 were reviewed retrospectively. The clinicopathological factors in the benign and malignant cases were compared to determine what features of the tumor could suggest malignant potential. RESULTS: Thirty patients with SPT were identified: 26 females and 4 males with

OncologyMedicine
13
Article|22 citations·2013
Predictive value of the Cincinnati Prehospital Stroke Scale for identifying thrombolytic candidates in acute ischemic stroke
Je Sung You, Sung Phil Chung, Hyun Soo Chung, Hye Sun Lee, Jong Woo Park, Hyun Jong Kim, Shin Ho Lee, Incheol Park, Hahn Shick Lee
SJR Q1The American Journal of Emergency MedicineOA
EpidemiologyMedicine
14
Article|21 citations·2018
Surgical Strategy for T2 Gallbladder Cancer: Nationwide Multicenter Survey in Korea
Seung Eun Lee, Sun‐Whe Kim, Ho‐Seong Han, Woo Jung Lee, Dong Sup Yoon, Baik‐Hwan Cho, In Seok Choi, Hyun Jong Kim, Soon‐Chan Hong, Sang‐Mok Lee, Dong Wook Choi, Sang‐Jae Park
SJR Q2Journal of Korean Medical ScienceOA

ECx including wedge resection of GB bed should be recommended for T2 GB cancer. Because systemic recurrence was more common and recurrence occurred more frequently in patients with LN metastasis, postoperative adjuvant therapy should be considered especially for the patients with LN metastasis.

SurgeryMedicine
15
Article|20 citations·2015
Expression of vasohibin-2 in pancreatic ductal adenocarcinoma promotes tumor progression and is associated with a poor clinical outcome.
Jung Chul Kim, Kyung Tae Kim, Jong‐Tae Park, Hyun Jong Kim, Yasufumi Sato, Hyung-Seok Kim
PubMed

This study aimed to assess the expression of vasohibin-2 (VASH2) in pancreatic ductal adenocarcinoma (PDAC) as a marker of tumor aggressiveness and its impact on tumor angiogenesis, proliferation, and clinical outcome. We examined the expression of the VASH2 gene in human pancreatic cell lines PANC-1 and MiaPaCa-2 by quantitative reverse transcription polymerase chain reaction (qRT-PCR) and immunocytochemistry. Fifty samples from patients with PDAC were immunostained with VASH2, CD34, and Ki-67

HematologyMedicine

Research Areas

SurgeryOncologyHepatologyPulmonary and Respiratory MedicineAerospace EngineeringEpidemiology

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