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Hyun-jun Hong

Yonsei University · Medicine

About the Lab

Professor Hyun-jun Hong's research lab specializes in head and neck surgical oncology and regenerative medicine, with a strong focus on improving surgical outcomes and developing innovative reconstructive techniques for head and neck defects. The lab investigates advanced surgical approaches such as modified facelift incisions in parotidectomy, evidence-based treatment protocols for oral cancer, and minimally invasive techniques like pulsed dye laser glottoplasty for voice disorders. A central theme in the lab’s work is tissue engineering, particularly using autologous and allogeneic chondrocytes combined with biocompatible hydrogels and scaffolds for tracheal reconstruction. The lab also explores risk stratification in stroke outcomes among patients with atrial fibrillation, reflecting a broader interest in clinical outcomes and patient-centered research.

tracheal reconstructiontissue engineeringhead and neck surgerysurgical oncologyregenerative medicine

Research Overview

Papers
163
Total Citations
1,146
Papers (5y)
97
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
97total
2021
2023
2024
2025
2026
Citations per year (5y)
89total
20212023202420252026

Selected Papers

15
1
Article|115 citations·2017
Guidelines for the Surgical Management of Laryngeal Cancer: Korean Society of Thyroid-Head and Neck Surgery
Korean Society of Thyroid-Head and Neck Surgery Guideline Task Force, Soon‐Hyun Ahn, Hyun Jun Hong, Soon Young Kwon, Kee Hwan Kwon, Jong‐Lyel Roh, Junsun Ryu, Jun Hee Park, Seung‐Kuk Baek, Guk Haeng Lee, Sei Young Lee, Jin‐Choon Lee
SJR Q1Clinical and Experimental OtorhinolaryngologyOA

Korean Society of Thyroid-Head and Neck Surgery appointed a Task Force to provide guidance on the implementation of a surgical treatment of oral cancer. MEDLINE databases were searched for articles on subjects related to "surgical management of oral cancer" published in English. Results were restricted to systematic reviews, randomized control trials/controlled clinical trials, and observational studies. The quality of evidence was rated with use RoBANS (Risk of Bias Assessment Tool for Nonrando

OtorhinolaryngologyMedicine
2
Article|107 citations·2012
Robot-assisted Supraomohyoid Neck Dissection via a Modified Face-lift or Retroauricular Approach in Early-stage cN0 Squamous Cell Carcinoma of the Oral Cavity: A Comparative Study with Conventional Technique
Hyoung Shin Lee, Won Shik Kim, Hyun Jun Hong, Myung Jin Ban, Dongwon Lee, Yoon Woo Koh, Eun Chang Choi
SJR Q1Annals of Surgical Oncology
OtorhinolaryngologyMedicine
3
Article|93 citations·2011
Radiotherapy Deteriorates Postoperative Functional Outcome After Partial Glossectomy With Free Flap Reconstruction
Yoo Seob Shin, Yoon Woo Koh, Se‐Heon Kim, Junhui Jeong, Sang Hyeon Ahn, Hyun Jun Hong, Eun Chang Choi
SJR Q1Journal of Oral and Maxillofacial Surgery
SurgeryMedicine
4
Article|85 citations·2011
Feasibility of Robot-Assisted Neck Dissections via a Transaxillary and Retroauricular (“TARA”) Approach in Head and Neck Cancer: Preliminary Results
Won Shik Kim, Hyoung Shin Lee, Sung Mi Kang, Hyun Jun Hong, Yoon Woo Koh, Hye Yeon Lee, Hong‐Shik Choi, Eun Chang Choi
SJR Q1Annals of Surgical Oncology
SurgeryMedicine
5
Article|53 citations·2011
Robot-Assisted Selective Neck Dissection via Modified Face-lift Approach for Early Oral Tongue Cancer: A Video Demonstration
Yoon Woo Koh, Woong Youn Chung, Hyun Jun Hong, So-Yoon Lee, Won Shik Kim, Hyoung Shin Lee, Eun Chang Choi
SJR Q1Annals of Surgical Oncology
NeurologyMedicine
6
Article|50 citations·2011
Early neurological outcomes according to CHADS2 score in stroke patients with non‐valvular atrial fibrillation
Hyun Jun Hong, Young Dae Kim, Myoung-Jin Cha, Jinkwon Kim, D. H. Lee, Hye Sun Lee, Chung Mo Nam, Hyo Suk Nam, Ji Hoe Heo
SJR Q1European Journal of Neurology

BACKGROUND AND PURPOSE: A higher CHADS(2) score or CHA(2)DS(2)-VASc score is associated with an increased risk of ischaemic stroke in patients with non-valvular atrial fibrillation (NVAF). However, there are no data regarding early neurological outcomes after stroke according to the risk levels. METHODS: In this study, a total of 649 stroke patients with NVAF were enrolled and categorized into three groups: low-risk (CHADS(2) score of 0-1), moderate-risk (CHADS(2) score 2-3), or high-risk group

Cardiology and Cardiovascular MedicineMedicine
7
Article|49 citations·2013
Robot-assisted versus endoscopic submandibular gland resection via retroauricular approach: a prospective nonrandomized study
Hyoung Shin Lee, Dae Hyun Kim, So Yoon Lee, Hyung Kwon Byeon, Won Shik Kim, Hyun Jun Hong, Yoon Woo Koh, Eun Chang Choi
SJR Q1British Journal of Oral and Maxillofacial SurgeryOA
SurgeryMedicine
8
Article|42 citations·2011
The Extended Indication of Parotidectomy Using the Modified Facelift Incision in Benign Lesions: Retrospective Analysis of a Single Institution
S.H. Lee, Yoon Woo Koh, Bo Gyung Kim, Hyun Jun Hong, Junhui Jeong, Eun Chang Choi
SJR Q1World Journal of SurgeryOA

BACKGROUND: Recently, the modified facelift incision (FLI) has gained increasing popularity for its cosmetic benefits in parotidectomy. However, many surgeons remain concerned with the adequacy of the exposure and are unwilling to use the FLI for anterior or superior tumors of the parotid gland because these tumors are closer to the superficially positioned facial nerve branch. To evaluate the changing trends in parotidectomy incisions for benign lesions at a single institute, and to compare the

SurgeryMedicine
9
Article|40 citations·2012
Transplantation of Autologous Chondrocytes Seeded on a Fibrin/Hyaluronan Composite Gel Into Tracheal Cartilage Defects in Rabbits: Preliminary Results
Hyun Jun Hong, Jin Seok Lee, Jae Won Choi, Byoung‐Hyun Min, Han‐Bin Lee, Chul‐Ho Kim
SJR Q2Artificial Organs

Reconstruction of tracheal defects is one of the most difficult procedures in head and neck surgery. To date, various reconstructing techniques have been used with no consensus on the best approach. This study investigated the feasibility of using a fibrin/hyaluronic acid (HA) composite gel with autologous chondrocytes for tracheal reconstruction. Chondrocytes from autologous rabbit auricular cartilages were expanded and seeded into a culture dish at high density to form stable tracheal cartilag

Pulmonary and Respiratory MedicineMedicine
10
Article|39 citations·2013
Use of Pulsed Dye Laser in the Treatment of Sulcus Vocalis
Chi Sang Hwang, Hyun Jin Lee, Jong‐Gyun Ha, Chang Il Cho, Na Hyun Kim, Hyun Jun Hong, Hong‐Shik Choi
SJR Q1OtolaryngologyOA

OBJECTIVE: The pulsed dye laser (PDL) has been shown to be effective in the treatment of hypertrophic scars and keloids in dermatology. On the basis of histopathologic similarities between sulcus vocalis and scar tissue and numerous reports on the treatment of laryngeal lesions, especially scar tissue, with PDL, we evaluated the efficacy of treating sulcus vocalis with PDL. We named this surgical procedure PDL glottoplasty. STUDY DESIGN: Case series with planned data collection. SETTING: A unive

DermatologyMedicine
11
Article|33 citations·2014
Tracheal reconstruction using chondrocytes seeded on a poly(l-lactic-co-glycolic acid)-fibrin/hyaluronan
Hyun Jun Hong, Jae Won Chang, Ju-Kyeong Park, Jae Won Choi, Yoo Suk Kim, Yoo Seob Shin, Chul‐Ho Kim, Eun Chang Choi
SJR Q1Journal of Biomedical Materials Research Part AOA

Reconstruction of trachea is still a clinical dilemma. Tissue engineering is a recent and promising concept to resolve this problem. This study evaluated the feasibility of allogeneic chondrocytes cultured with fibrin/hyaluronic acid (HA) hydrogel and degradable porous poly(L-lactic-co-glycolic acid) (PLGA) scaffold for partial tracheal reconstruction. Chondrocytes from rabbit articular cartilage were expanded and cultured with fibrin/HA hydrogel and injected into a 5 × 10 mm-sized, curved patch

Pulmonary and Respiratory MedicineMedicine
12
Article|32 citations·2013
Transoral Robotic Retropharyngeal Lymph Node Dissection With or Without Lateral Oropharyngectomy
Hyung Kwon Byeon, Umamaheswar Duvvuri, Won Shik Kim, Young Min Park, Hyun Jun Hong, Yoon Woo Koh, Eun Chang Choi
SJR Q2Journal of Craniofacial SurgeryOA

Retropharyngeal lymph node (RPLN) metastases can occur from advanced head and neck malignancies. Surgical access to RPLNs can be challenging. Considering the more aggressive conventional approach methods, there is an increasing need for minimally invasive techniques. Applying transoral robotic surgery (TORS) to access the RPLN has never been reported in the literature. The purpose of this study was to describe our experience with transoral robotic RPLN dissection for oropharyngeal and hypopharyn

OtorhinolaryngologyMedicine
13
Article|30 citations·2011
Endoscopic Thyroidectomy via an Axillo-Breast Approach without Gas Insufflation for Benign Thyroid Nodules and Micropapillary Carcinomas: Preliminary Results
Hyun Jun Hong, Won Shik Kim, Yoon Woo Koh, So Yoon Lee, Yoo Seob Shin, Yong Cheol Koo, Yoon A Park, Eun Chang Choi
SJR Q2Yonsei Medical JournalOA

PURPOSE: To examine the feasibility of endoscopic thyroidectomy (ET) via an axillo- breast approach without gas insufflation for large thyroid tumors and micropapillary carcinomas. MATERIALS AND METHODS: The patients in the benign group were separated into groups 1 (n=95, <4 cm in tumor diameter) and 2 (n=37, ≥4 cm in tumor diameter). Also, 57 patients in the micropapillary carcinoma group underwent an endoscopic hemithyroidectomy (HT) (group 3) and were compared with 60 patients who received co

SurgeryMedicine
14
Article|20 citations·2011
Endoscopic Thyroidectomy via an Axillo-Breast Approach without Gas Insufflation for Benign Thyroid Nodules and Micropapillary Carcinomas: Preliminary Results
홍현준, 고윤우, 김원식, 이소윤, 신유섭, 구용철, 박윤아, 최은창
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120110520040643

Purpose: To examine the feasibility of endoscopic thyroidectomy (ET) via an axillo-breast approach without gas insufflation for large thyroid tumors and micropapillary carcinomas. Materials and Methods: The patients in the benign group were separated into groups 1 (n=95, <4 cm in tumor diameter) and 2 (n=37, ≥4 cm in tumor diameter). Also, 57 patients in the micropapillary carcinoma group underwent an endoscopic hemithyroidectomy (HT) (group 3) and were compared with 60 patients who received con

15
Article|5 citations·2013
Carcinoma Ex Pleomorphic Adenoma in the Oral Cavity
Hyun Jun Hong, Hyung Kwon Byeon, Seong Hoon Bae, Ah Young Park, Eun Chang Choi, Hong‐Shik Choi
SJR Q2Journal of Craniofacial SurgeryOA

Carcinoma ex pleomorphic adenoma (CEPA) is a rare, aggressive, poorly understood malignancy. In CEPA, an epithelial malignancy develops in association with a primary or recurrent benign pleomorphic adenoma. Carcinoma ex pleomorphic adenoma is very difficult to identify before surgery because the clinical presentation of many cases is similar to that of pleomorphic adenomas. The risk for malignancy increases with the duration of a mixed tumor. Treatment of CEPA must be individualized on the basis

SurgeryMedicine

Research Areas

OncologyOtorhinolaryngologySurgeryPulmonary and Respiratory MedicineMolecular BiologyNeurology

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