Hyun Keun Lim
Sungkyunkwan University · Medicine
About the Lab
Professor Hyun Keun Lim's research lab specializes in diagnostic and interventional radiology, with a strong focus on ultrasound-based imaging techniques for accurate diagnosis and image-guided interventions. The lab investigates advanced ultrasound applications—such as color Doppler sonography and elastography—in challenging clinical scenarios, including acute appendicitis in pregnancy and small liver tumors. Key research directions include improving the diagnostic accuracy of medical imaging through hemodynamic and perfusion parameters, particularly in hepatocellular carcinoma and uterine fibroids, using techniques like DCE-MRI and sonoelastography. The lab also emphasizes the development and validation of predictive models for treatment outcomes using clinical and imaging biomarkers.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15OBJECTIVE: We compared surgical resection (SR) and radiofrequency ablation (RFA) as first-line treatment in patients with hepatocellular carcinoma (HCC) based on the risk of microvascular invasion (MVI). BACKGROUND: The best curative treatment modality between SR and RFA in patients with HCC with MVI remains unclear. METHODS: Data from 2 academic cancer center-based cohorts of patients with a single, small (≤3 cm) HCC who underwent SR were used to derive (n = 276) and validate (n = 101) predicti
Our experience suggests that graded-compression sonography is a valuable procedure for detecting acute appendicitis in pregnant women despite technical difficulty in performing it during the third trimester of pregnancy.
US is sensitive and specific in the diagnosis of intussusception, and CDS is a promising predictor of bowel viability.
Hyperemia in the wall of the appendix at color Doppler US is a sensitive indicator for inflammation. A simple additional color Doppler US examination may be helpful in the diagnosis of early acute appendicitis when an appendix is well depicted and is equivocal in size at gray-scale US.
: A higher K value at baseline DCE-MRI suggested a poor ablation efficacy of MR-HIFU therapy for symptomatic uterine fibroids.
Although US appears to be fairly accurate in the diagnosis of focal appendicitis confined to the tip, the entire length of the appendix should be evaluated in order to avoid a false-negative diagnosis.
OBJECTIVE: To evaluate the utility of gray scale harmonic ultrasonography with a microbubble contrast agent in the early assessment of the therapeutic response to radio frequency ablation for hepatocellular carcinoma. METHODS: Seventy-five patients with 81 nodular hepatocellular carcinomas (1.3-4.8 cm) treated with percutaneous radio frequency ablation were evaluated with contrast-enhanced gray scale harmonic ultrasonography after intravenous bolus injection of a galactose-based microbubble cont
Early 3D-CRT for HCC unresponsive to 1 or 2 cycles of TACE resulted in a 62.8% tumor response rate and relatively high complete response rates (20.9%) with acceptable toxicity. This study shows that the application of 3D-CRT could be considered for patients with incomplete TACE.
Research Areas
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