Hyun-Kyeom Park
Hanyang University · Medicine
About the Lab
Professor Hyun-Kyeom Park's research lab specializes in surgical oncology and advanced abdominal surgery, with a focus on rare and complex gastrointestinal malignancies, including hepatoid adenocarcinoma, acinar cell carcinoma of the pancreas, and gallbladder tumors. The lab investigates diagnostic challenges, surgical management, and prognostic factors in these rare neoplasms, often emphasizing the role of immunohistochemistry and imaging in accurate diagnosis. Additionally, the lab explores innovative surgical techniques and biomaterials for urological and hepato-biliary reconstruction, such as the use of bovine pericardium in bladder repair and surgical treatment of polycystic liver disease.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
13Hepatoid adenocarcinoma (HAC) is a tumor with aberrant hepatocellular differentiation that occurs in extrahepatic organs. HAC of the gallbladder is rare, and cases of alpha-fetoprotein production are extremely rare. A 61-year-old man was diagnosed with gallbladder adenocarcinoma after laparoscopic cholecystectomy. A radical operation including resection of liver bed and lymph node dissection was performed, and no tumor cell was found. However, at postoperative 19 months, he showed lymphadenopath
Acinar cell carcinoma (ACC) of the pancreas is a rare malignancy making up approximately 1% of pancreatic non-endocrine malignant tumors. The common finding on computed tomography is a solitary, well-defined, heterogenous hypodense mass with enhancing capsule. ACC is a highly cellular tumor with minimal stroma and a lack of stromal desmoplasia. The accurate diagnosis of ACC cannot typically be done by histology alone but rather requires immunohistochemical staining or electron microscopy for the
결장 정맥류는 하부 위장관 출혈을 유발하는 매우 드문 질환으로 다양한 원인에 의해 발생한다. 일단 출혈이 발생하면 식도 정맥류 출혈보다 매우 치명적이다. Klippel-Trenaunay-Weber 증후군은 모세혈관기형, 심부 정맥류, 사지의 기형 등이 특징인 드문 질환이다. 저자는 전신과 안면에 혈관 확장, 대장 내시경검사에서 S자결장 정맥류가 있고, 상대 정맥과 하대 정맥이 동시에 폐쇄되었으며 신체 기형이 있는 Klippel-Trenaunay- Weber 증후군 환자에서 심한 정맥류 출혈로 S자결장 부분절제술을 시행한 예를 경험하였기에 문헌 고찰과 함께 보고한다.
Background/Aims: The pattern of chromosomal gains and losses in HCC with hepatitis B in Korean patients is very complex and involves virtually every site in the genome. This study was done to know the chromosomal aberrations in hepatocellular carcinoma with HBV and relationship between these lesions and previously known oncogenes and tumor suppressor genes. Methods: DNA changes in 23 hepatocellular carcinomas (HCC) associated with hepatitis B virus (HBV) were analyzed by CGH technique. Results:
Injuries of the inferior vena cava (IVC) might be caused by a blunt trauma, which usually affects the retrohepatic portion. Injuries of the infrahepatic IVC are usually caused by penetrating injuries and rarely occur in Korea. We report a case of a penetrating injury of the IVC at the infrahepatic suprarenal portion with a review of other reported cases. (J Korean Surg Soc 2003;64:447-450)
Purpose: Multiple primary cancers are not a rare disease. The clinicopathologic characteristics of a hepatocellular carcinoma with extrahepatic malignancies, have not been identified. To address these points, the clinical data of patients with a hepatocellular carcinoma, with extrahepatic malignancies, treated with surgical resections at our hospital, were retrospectively reviewed. Methods: We reviewed the clinical records of ten hepatocellular carcinoma patients, with extrahepatic malignancies,
A primary hepatic sarcoma is a rare tumor, that most frequently arises from hepatic connective tissue or vascular channels, and is usually located in the intrahepatic area. Pedunculated, or bulging, lesions have also been reported. We encountered a pedunculated primary hepatic leiomyosarcoma occurring in a 61-year-old woman. A giant exophytic hepatic mass measuring 15x10cm in size, was located in the left lateral segment of the liver, which was compressing the stomach. A left lateral segmentecto
Adult polycystic liver disease (APLD) is an inherited, benign rare condition, often associated with polycystic kidney disease. Liver failure is unusual, but some patients may require therapy. Surgery appears to be more effective in relieving the symptoms of APLD for an extended period than nonsurgical therapies. We report on the successful surgical treatment of a case of APLD located in the left lobe of the liver. (J Korean Surg Soc 2002;63:171-174)
The use of graft materials in bladder mucosa has been examined in animal models, but debate exists over which materials are effective. Intestine has been used as a substitute in augmentation cystoplasty for patients with neuropathic bladder, but serious adverse effects of the operation have occurred in some instances. We report a case of a successful repair of an enterovesical fistula by use of bovine pericardium. The patient has remained well for 2.5 years. We suggest that bovine pericardium ma
목적: 췌장의 선방 세포암은 외분비선에서 발생하는 종양으로 1-2%를 차지하는 매우 드문 악성종양이다. 국내의 선방 세포암에 대한 연구는 미흡한 실정이다. 이번 연구는 국내에서 보고된 선방 세포암에 대해 임상양상, 병리학적 특징, 치료와 예후를 알아보고자 시작되었다. 대상 및 방법: 2009년 10월까지 국내에 보고된 논문을 검색하여 병리학적으로 췌장 선방 세포암으로 확인된 총 27예의 환자와 본원에서 경험한 2예를 포함하여 총 29예에 대해 임상양상, 방사선 소견, 면역조직염색검사를 포함한 병리학적 특징, 수술과 재발 유무, 보조요법과 생존여부를 조사하였다. 이와 함께 외국의 연구와 비교하여 국내 선방 세포암의 특징을 고찰하였다. 결과: 선방 세포암은 50대의 남자에서 호발하며, 증상으로는 복부 동통과 종괴가 흔하다. 췌장 미부(41.4%)의 발생 빈도가 높았으며, 크기도 평균 7 cm으로 큰 양상을 보였다. 진단 당시 간 전이가 흔하고, 술 후 재발은 대부분 18개월 이내에 발생
Research Areas
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