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Hyun-pil Shin

Kyung Hee University · Medicine

About the Lab

Professor Hyun-pil Shin's research lab specializes in gastrointestinal and hepatobiliary diseases, with a focus on biliary stent management, pancreatic cancer prognosis, and viral hepatitis treatment. The lab investigates clinical outcomes and risk stratification in advanced neoplasia and chronic liver disease, emphasizing endoscopic interventions, metabolic imaging (e.g., FDG-PET SUVmax), and antiviral therapy in patients with renal impairment. Their work also explores molecular mechanisms of pancreatitis and the therapeutic potential of natural compounds like Korean red ginseng in inflammatory conditions.

biliary stentspancreatic cancerHCV treatmentSUVmaxKorean red ginseng

Research Overview

Papers
208
Total Citations
2,053
Papers (5y)
21
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
21total
2021
2022
2023
2024
2025
Citations per year (5y)
237total
20212022202320242025

Selected Papers

15
1
Article|62 citations·2006
Endoscopic removal of biliary self-expandable metallic stents: a prospective study
Hyun Phil Shin, M.-H. Kim, S. Jung, Jong‐Hoon Kim, Eugene Choi, Jimin Han, S. Lee, Dong Wan Seo, S. Lee
SJR Q1Endoscopy

In contrast to uncovered biliary SEMSs, in most cases malfunctioning covered biliary SEMSs can be easily and safely removed endoscopically using a rat-tooth forceps.

SurgeryMedicine
2
Article|60 citations·2013
Predictive Value of Maximum Standardized Uptake Value (SUVmax) on 18F-FDG PET/CT in Patients With Locally Advanced or Metastatic Pancreatic Cancer
Soo Young Moon, Kwang Ro Joo, Ye Ri So, Jun Uk Lim, Jae Kyung Myung, Hyun Phil Shin, You-Jung Yang
SJR Q2Clinical Nuclear Medicine

Higher SUVmax of primary pancreatic tumor is associated with poor PFS and pretreatment SUVmax is an independent prognostic factor for predicting PFS in patients with locally advanced or metastatic pancreatic cancer who received gemcitabine-based palliative chemotherapy. However, pretreatment SUVmax is not associated with chemotherapeutic response.

Radiology, Nuclear Medicine and ImagingMedicine
3
Article|60 citations·2014
Development and Validation of a Risk Stratification-based Screening Model for Predicting Colorectal Advanced Neoplasia in Korea
Dong Hyun Kim, Jae Myung, Hyun Phil Shin, Kwang Ro Joo, Joung Il Lee, Dong Il Park
SJR Q2Journal of Clinical Gastroenterology

KCS score may be clinically simple and useful for assessing advanced neoplasia risk in Korea. However, racial disparity should be considered in risk stratification-based screening in each country.

OncologyMedicine
4
Article|39 citations·2012
The risk of postpolypectomy bleeding during colonoscopy in patients with early liver cirrhosis
Jung Won Jeon, Hyun Phil Shin, Joung Il Lee, Kwang Ro Joo, Kwan Mi Pack, Jae Myung, Jae Jun Park, Jun Uk Lim, Kyu-Seong Lim
SJR Q1Surgical Endoscopy
OncologyMedicine
5
Article|36 citations·2000
Prevalence and risk factors of hepatitis C virus infection among Koreans in rural area of Korea
Hyun Phil Shin
SJR Q1Hepatology Research
HepatologyMedicine
6
Article|25 citations·2017
Efficacy and safety of sofosbuvir-based regimens for treatment in chronic hepatitis C genotype 1 patients with moderately impaired renal function
Hyun Phil Shin, Ji Ae Park, Blaire E. Burman, Richard A. Kozarek, Asma Siddique
SJR Q1Clinical and Molecular HepatologyOA

SOF-based regimens resulted in high SVR12 rates in patients with moderately impaired renal function. During therapy, HCV patients with CKD should be carefully monitored for worsening renal function.

HepatologyMedicine
7
Article|22 citations·2018
Real-world single-center experience with entecavir and tenofovir disoproxil fumarate in treatment-naïve and experienced patients with chronic hepatitis B
Hyun Phil Shin, Young-Min Kim, JoungIl Lee, KwangRo Joo, JaeMyung Cha, JungWon Jeon, Jin Young Yoon, Min Seob Kwak
SJR Q2Saudi Journal of GastroenterologyOA

Both ETV and TDF therapy resulted in a high CVR, and the annual incidence rates of HCC and other cirrhosis-related complications were not significantly different between the two treatment groups.

EpidemiologyMedicine
8
Article|15 citations·2009
Effect of Korean Red Ginseng on Superoxide Dismutase Inhibitor-Induced Pancreatitis in Rats
Kwang Ro Joo, Hyun Phil Shin, Jae Kyung Myung, Sua Nam, Youngbuhm Huh
SJR Q2Pancreas

Our results suggest that KRG has antioxidant therapeutic effects on superoxide dismutase inhibitor-induced pancreatitis by inhibition of nuclear factor kappaB.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
Article|14 citations·2011
A case of leukemoid reaction in a patient with sarcomatous hepatocellular carcinoma
Hyun Phil Shin, Jung Won Jeon, Jae Jun Park, Jae Myung, Kwang Ro Joo, Joung Il Lee, Gou Young Kim, So Young Kang
The Korean Journal of HepatologyOA

A leukemoid reaction is defined as reactive leukocytosis exceeding 50,000/mm(3), with a significant increase in early neutrophil precursors, and can be a paraneoplastic manifestation of various malignant tumors. A 71-year-old male patient complained of decreased appetite, fatigue, and abdominal fullness. He had a palpable, firm liver, and laboratory investigations suggested leukemoid reaction. Liver dynamic computed tomography revealed a hypervascular mass, and an ultrasound-guided fine-needle a

RheumatologyMedicine
10
Article|14 citations·2023
Efficacy of Transarterial Chemoembolization (TACE) for Early-Stage Hepatocellular Carcinoma
Moonhyung Lee, Hyun Phil Shin
SJR Q2MedicinaOA

Backgound and Objectives: The treatments of choice for patients with early-stage hepatocellular carcinoma (HCC) are surgical resection, local ablation therapy, and liver transplantation; however, transarterial chemoembolization (TACE) is commonly performed due to variations among patients and liver diseases. This study aimed to assess the efficacy of TACE in patients with early-stage HCC. Materials and Methods: A retrospective analysis was performed of all TACE procedures performed at Kyung Hee

HepatologyMedicine
11
Article|13 citations·2014
Needle-Knife Fistulotomy With Percutaneous Transhepatic Cholangioscopy for Managing Complete Bilioenteric Anastomosis Occlusion
Jun Uk Lim, Kwang Ro Joo, Jae Kyung Myung, Hyun Phil Shin, Joung Il Lee, Jae Jun Park, Jung Won Jeon
SJR Q2Surgical Laparoscopy Endoscopy & Percutaneous Techniques

Untreated benign biliary stricture can lead to serious complications including recurrent cholangitis, biliary cirrhosis, hepatic failure, and death. Benign stricture of a postoperative anastomosis site is also a problematic issue after biliary surgery. Percutaneous transhepatic cholangioscopy (PTCS) with balloon dilatation is a recently introduced noninvasive therapeutic option for biliary stricture. Guidewire insertion through the stricture site is essential for the success of PTCS treatment. R

Pulmonary and Respiratory MedicineMedicine
12
Article|12 citations·2017
Clinical Predictors for KRAS Codon 13 Mutations in Patients With Colorectal Cancer
Min Seob Kwak, Jae M., Young H. Cho, Sang Hyun Kim, Jin Young Yoon, Jung Won Jeon, Hyun Phil Shin, Kwang Ro Joo, Joung I. Lee
SJR Q2Journal of Clinical Gastroenterology

GOALS: This study sought to clarify sex differences in KRAS mutations and clinical predictors of KRAS 13 codon mutations. BACKGROUND: Sex differences in KRAS mutations and predictors for KRAS codon 13 mutations in colorectal cancer (CRC) are unclear. STUDY: Between October 2007 and May 2016, 328 patients underwent surgery for CRCs that were analyzed for KRAS mutations at a referral university hospital. Sex differences in the rates and distributions of KRAS mutations, and factors predictive of ov

OncologyMedicine
13
Review|8 citations·2023
Endoscopic resection of early gastric cancer
Hyun Phil Shin, Su Bee Park, Hye Ran Seo, Jung Won Jeon
SJR Q2Journal of Exercise RehabilitationOA

Endoscopic resection (ER) is an effective treatment for early gastric cancer (EGC) without metastases. Existing endoscopic mucosal resec-tion (EMR) is easy to perform, has few complications, and can be ap-plied when the lesion size is small. However, <i>en bloc</i> and complete re-section rates vary depending on the size and severity of the lesion. EMR using the cap-mounted panendoscopic method and EMR after circum-ferential preamputation of the lesion are useful in the treatment of

Pulmonary and Respiratory MedicineMedicine
14
Article|7 citations·2007
Matrix Metalloproteinase (MMP)-3 Polymorphism in Patients with HBV Related Chronic Liver Disease
Hyun Phil Shin, Joung Il Lee, Joo-Ho Jung, Sung‐Vin Yim, Hyun Jeong Kim, Jae Myung, Jong Beom Park, Kwang Ro Joo, Jae Seok Hwang, Byoung Kuk Jang
SJR Q2Digestive Diseases and Sciences
SurgeryMedicine
15
Article|7 citations·2017
Real-World Single-Center Experience with Sofosbuvir-Based Regimens for the Treatment of Chronic Hepatitis C Genotype 1 Patients
Hyun Phil Shin, Blaire E. Burman, Richard A. Kozarek, Amy Zeigler, Chia Wang, Houghton Lee, Troy Zehr, Alicia Edwards, Asma Siddique
SJR Q1Gut and LiverOA

In this single-center, real-world setting, the treatment of chronic HCV G1 resulted in a high rate of SVR, especially in patients without cirrhosis.

HepatologyMedicine

Research Areas

OncologySurgeryHepatologyPulmonary and Respiratory MedicineAerospace EngineeringEpidemiology

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