Hyun-Woo Bae
Yonsei University · Medicine
About the Lab
Professor Hyun-Woo Bae's research lab specializes in colorectal surgery and gastrointestinal oncology, with a strong focus on improving surgical outcomes for rectal and colorectal cancers. The lab investigates advanced surgical techniques such as total mesorectal excision (TME) and intersphincteric resection (ISR), emphasizing nerve-sparing approaches and complication prevention. It also explores predictive biomarkers, including preoperative perineural invasion and micrometastasis, to guide personalized treatment and improve survival. Additionally, the lab examines cost-effective treatment strategies like short-course radiotherapy and long-term outcomes in inflammatory bowel disease and Behçet’s disease.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
12SCRT was well-tolerated and achieved favorable short-term outcomes. In addition, SCRT showed significant reduction in the total cost of care and distinguished cost-effectiveness compared to LCRT.
Total mesorectal excision (TME) has greatly improved rectal cancer surgery outcomes by reducing local recurrence and enhancing patient survival. This review outlines essential knowledge and techniques for performing TME. TME emphasizes the complete resection of the mesorectum along embryologic planes to minimize recurrence. Key anatomical insights include understanding the rectal proper fascia, Denonvilliers fascia, rectosacral fascia, and the pelvic autonomic nerves. Technical tips cover a step
Radical resection for low rectal cancer is the mainstay among the treatment modalities. Intersphincteric resection (ISR) is considered a relatively new but effective surgical treatment for low-lying rectal tumor. As the sphincter preserving techniques get popularized, we notice uncommon complication associated with it in the form of rectal mucosal prolapse. We presented 2 rare cases that developed neorectal mucosa prolapse after ISR a complication following low rectal cancer surgery. Although IS
Preoperative PNI could serve as a predictive factor for PICs in CD patients who undergo intestinal resection. Additionally, PICs are significantly associated with a higher risk of surgical recurrence in CD.
BACKGROUND: This study investigated the impact of pN1mi disease on the survival of T1 breast cancer patients and examined the clinical usefulness of the online PREDICT tool and updated staging system. METHODS: The node stages of 2344 patients were divided into pN0, pN1mi, and pN1a. Clinicopathological parameters and survival outcomes were retrospectively analyzed. Data for 111 micrometastatic diseases were applied to the PREDICT version 2.0 and re-classified using the 8th edition of the cancer s
Background/Objectives: Intestinal Behçet’s disease (iBD) often requires surgical intervention, with a significant proportion of patients needing reoperation. This study aimed to investigate the risk factors associated with reoperation in patients with iBD who underwent initial bowel resection and to evaluate the perioperative and long-term outcomes in these patients. Methods: This was a retrospective case-control study analyzing patients who underwent their initial bowel resection due to iBD bet
Abstract The aim of rectal cancer surgery is to achieve a curative resection by completely removing the rectum involved with cancer surrounding the mesorectum, obtaining a safe adequate resection margin, and preserving important structures crucial for the patient's quality of life. Optimal dissection along the avascular embryological fusion line and among deep invisible structures is essential. Whereas a minimally invasive surgical approach allows for better visibility of deep pelvic structures
LSA not only provides a safe alternative but also offers a resource-efficient option for wound management compared to staplers.
S core/shell nanoplatelets (NPLs) with a chemical composition gradient, enabled by the introduction of halide ions, which promote the formation of a uniform-thickness shell. The use of a compositionally graded shell eliminates abrupt interfaces between the core and shell, leading to both high photoluminescence quantum yield and enhanced photostability. This graded shell architecture also induces significant Stokes shift, particularly due to heterogeneous growth of the NPL vertices, thereby effec
Abstract Background: Long-course chemoradiotherapy (LCRT) has been widely recommended in a majority of rectal cancer patients. Recently, encouraging data on short-course radiotherapy (SCRT) for rectal cancer has emergedWe aimed to compare these two methods in terms of short-term outcomes and cost analysis under Korean medical insurance system. Materials and methods: 62 patients with high-risk rectal cancer underwent either SCRT or LCRT followed by total mesorectal excision (TME) and classified i
BACKGROUND: Neuromuscular blocking agents (NMBAs) are the leading cause of perioperative anaphylaxis. In confirmed cases with limited non-cross-reactive options, safe anesthesia requires coordination and muscle relaxant-free strategies. CASE: A 64-year-old woman with confirmed rocuronium-induced anaphylaxis and multiple comorbidities-including poorly controlled diabetes, coronary artery disease, chronic obstructive pulmonary disease, and obesity-underwent laparoscopic anterior resection of the s
Research Areas
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