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Hyun-Woo Bae

Yonsei University · Medicine

About the Lab

Professor Hyun-Woo Bae's research lab specializes in colorectal surgery and gastrointestinal oncology, with a strong focus on improving surgical outcomes for rectal and colorectal cancers. The lab investigates advanced surgical techniques such as total mesorectal excision (TME) and intersphincteric resection (ISR), emphasizing nerve-sparing approaches and complication prevention. It also explores predictive biomarkers, including preoperative perineural invasion and micrometastasis, to guide personalized treatment and improve survival. Additionally, the lab examines cost-effective treatment strategies like short-course radiotherapy and long-term outcomes in inflammatory bowel disease and Behçet’s disease.

rectal cancersurgical oncologysphincter preservationperineural invasioncolorectal surgery outcomes

Research Overview

Papers
12
Total Citations
51
Papers (5y)
11
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
11total
2021
2023
2024
2025
2026
Citations per year (5y)
45total
20212023202420252026

Selected Papers

12
1
Article|11 citations·2023
Short-Term Outcomes and Cost-Effectiveness between Long-Course Chemoradiation and Short-Course Radiotherapy for Locally Advanced Rectal Cancer
Min Soo Cho, Hyeon Woo Bae, Jee Suk Chang, Seung Yoon Yang, Tae Hyun Kim, Woong Sub Koom, Sang Joon Shin, Gyu‐Seog Choi, Nam Kyu Kim
SJR Q2Yonsei Medical JournalOA

SCRT was well-tolerated and achieved favorable short-term outcomes. In addition, SCRT showed significant reduction in the total cost of care and distinguished cost-effectiveness compared to LCRT.

OncologyMedicine
2
Review|11 citations·2024
Essential knowledge and technical tips for total mesorectal excision and related procedures for rectal cancer
Min Soo Cho, Hyeon Woo Bae, Nam Kyu Kim
SJR Q2Annals of ColoproctologyOA

Total mesorectal excision (TME) has greatly improved rectal cancer surgery outcomes by reducing local recurrence and enhancing patient survival. This review outlines essential knowledge and techniques for performing TME. TME emphasizes the complete resection of the mesorectum along embryologic planes to minimize recurrence. Key anatomical insights include understanding the rectal proper fascia, Denonvilliers fascia, rectosacral fascia, and the pelvic autonomic nerves. Technical tips cover a step

OncologyMedicine
3
Article|8 citations·2021
Neorectal Mucosal Prolapse After Intersphincteric Resection for Low-Lying Rectal Cancer: A Case Report
Mohammed Alessa, Hyeon Woo Bae, Homoud Alawfi, Ahmad Sakr, Fozan Sauri, Nam Kyu Kim
SJR Q2Annals of ColoproctologyOA

Radical resection for low rectal cancer is the mainstay among the treatment modalities. Intersphincteric resection (ISR) is considered a relatively new but effective surgical treatment for low-lying rectal tumor. As the sphincter preserving techniques get popularized, we notice uncommon complication associated with it in the form of rectal mucosal prolapse. We presented 2 rare cases that developed neorectal mucosa prolapse after ISR a complication following low rectal cancer surgery. Although IS

OncologyMedicine
4
Article|7 citations·2024
Clinical Significance of Prognostic Nutrition Index in Patients with Crohn’s Disease after Primary Bowel Resection
Hyeon Woo Bae, Yong Joon Lee, Min Young Park, Seung Yoon Yang, Yoon Dae Han, Min Soo Cho, Hyuk Hur, Kang Young Lee, Jae Hee Cheon, Joseph C. Carmichael, Byung Soh Min
SJR Q2Yonsei Medical JournalOA

Preoperative PNI could serve as a predictive factor for PICs in CD patients who undergo intestinal resection. Additionally, PICs are significantly associated with a higher risk of surgical recurrence in CD.

GeneticsBiochemistry, Genetics and Molecular Biology
5
Article|6 citations·2018
Impact of Micrometastatic Axillary Nodes on Survival of Breast Cancer Patients with Tumors ≤2 cm
Hyeon Woo Bae, Kwang Hyun Yoon, Joo Heung Kim, Sung Mook Lim, Jee Ye Kim, Hyung Seok Park, Seho Park, Seung Il Kim, Young Up Cho, Byeong‐Woo Park
SJR Q1World Journal of SurgeryOA

BACKGROUND: This study investigated the impact of pN1mi disease on the survival of T1 breast cancer patients and examined the clinical usefulness of the online PREDICT tool and updated staging system. METHODS: The node stages of 2344 patients were divided into pN0, pN1mi, and pN1a. Clinicopathological parameters and survival outcomes were retrospectively analyzed. Data for 111 micrometastatic diseases were applied to the PREDICT version 2.0 and re-classified using the 8th edition of the cancer s

Cancer ResearchBiochemistry, Genetics and Molecular Biology
6
Article|4 citations·2021
Upfront chemotherapy and short-course radiotherapy with delayed surgery for locally advanced rectal cancer with synchronous liver metastases
Hyeon Woo Bae, Ho Seung Kim, Seung Yoon Yang, Han Sang Kim, Sang Joon Shin, Jee Suk Chang, Woong Sub Koom, Nam Kyu Kim
SJR Q1European Journal of Surgical OncologyOA
OncologyMedicine
7
Article|2 citations·2024
Risk Factors of Reoperation in Patients with Intestinal Behçet’s Disease Treated by Initial Bowel Resection
Sun Jung Kim, Eun Ji Park, Hyeon Woo Bae, Yong Joon Lee, Min Young Park, Seung Yoon Yang, Yoon Dae Han, Min Soo Cho, Hyuk Hur, Joseph C. Carmichael, Byung Soh Min, Kang Young Lee
SJR Q1Journal of Clinical MedicineOA

Background/Objectives: Intestinal Behçet’s disease (iBD) often requires surgical intervention, with a significant proportion of patients needing reoperation. This study aimed to investigate the risk factors associated with reoperation in patients with iBD who underwent initial bowel resection and to evaluate the perioperative and long-term outcomes in these patients. Methods: This was a retrospective case-control study analyzing patients who underwent their initial bowel resection due to iBD bet

OphthalmologyMedicine
8
Article|1 citations·2023
Optimal surgical techniques for curative resection of the rectal cancer
Hyeon Woo Bae, Nam Kyu Kim
SJR Q4Formosan Journal of SurgeryOA

Abstract The aim of rectal cancer surgery is to achieve a curative resection by completely removing the rectum involved with cancer surrounding the mesorectum, obtaining a safe adequate resection margin, and preserving important structures crucial for the patient's quality of life. Optimal dissection along the avascular embryological fusion line and among deep invisible structures is essential. Whereas a minimally invasive surgical approach allows for better visibility of deep pelvic structures

OncologyMedicine
9
Article|1 citations·2025
A randomized controlled trial comparing liquid skin adhesives and staplers for surgical wound management
Hyeon Woo Bae, Seung Yoon Yang, Ga Yoon Ku, S.K. Lee, Eun Joo Jung, Seulkee Park, Yoon Bin Jung, Jihong Kim, Byung Soh Min
SJR Q2Annals of Surgical Treatment and ResearchOA

LSA not only provides a safe alternative but also offers a resource-efficient option for wound management compared to staplers.

SurgeryMedicine
10
Article|0 citations·2026
Halide-assisted Al-doped graded shells for emission tunability and photostability in CdSe NPLs
Hyeon Woo Bae, Thi Kim Tuyen Nguyen, Jaehan Jung
SJR Q1Scientific ReportsOA

S core/shell nanoplatelets (NPLs) with a chemical composition gradient, enabled by the introduction of halide ions, which promote the formation of a uniform-thickness shell. The use of a compositionally graded shell eliminates abrupt interfaces between the core and shell, leading to both high photoluminescence quantum yield and enhanced photostability. This graded shell architecture also induces significant Stokes shift, particularly due to heterogeneous growth of the NPL vertices, thereby effec

Materials ChemistryMaterials Science
11
Preprint|0 citations·2023
Short-term outcomes and cost-effectiveness between long-course chemoradiation and short-course radiotherapy followed by consolidation chemotherapy for the treatment of locally advanced rectal cancer
Min Soo Cho, Hyeon Woo Bae, Jee Suk Chang, Seung Yoon Yang, Tae Hyun Kim, Woong Sub Koom, Sang Jun Shin, Gyu‐Seog Choi, Nam Kyu Kim
Research SquareOA

Abstract Background: Long-course chemoradiotherapy (LCRT) has been widely recommended in a majority of rectal cancer patients. Recently, encouraging data on short-course radiotherapy (SCRT) for rectal cancer has emergedWe aimed to compare these two methods in terms of short-term outcomes and cost analysis under Korean medical insurance system. Materials and methods: 62 patients with high-risk rectal cancer underwent either SCRT or LCRT followed by total mesorectal excision (TME) and classified i

OncologyMedicine
12
Article|0 citations·2026
General anesthesia without neuromuscular blocking agents using regional blocks in rocuronium-induced anaphylaxis - A case report -
Ji Young Kim, Young Chul Yoo, Na Young Kim, Hyeon Woo Bae, Soo Jung Park
SJR Q2Anesthesia and Pain MedicineOA

BACKGROUND: Neuromuscular blocking agents (NMBAs) are the leading cause of perioperative anaphylaxis. In confirmed cases with limited non-cross-reactive options, safe anesthesia requires coordination and muscle relaxant-free strategies. CASE: A 64-year-old woman with confirmed rocuronium-induced anaphylaxis and multiple comorbidities-including poorly controlled diabetes, coronary artery disease, chronic obstructive pulmonary disease, and obesity-underwent laparoscopic anterior resection of the s

Anesthesiology and Pain MedicineMedicine

Research Areas

OncologyGeneticsCancer ResearchOphthalmologySurgeryMaterials Chemistry

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