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Hyung-Jung Lee

Hanyang University · Medicine

About the Lab

Professor Hyung-Jung Lee's research lab specializes in cerebrovascular diseases, with a primary focus on aneurysmal subarachnoid hemorrhage (aSAH) and intracerebral hemorrhage. The lab investigates prognostic factors, neuroprotective treatments such as Cerebrolysin, and environmental influences—including meteorological and air pollution factors—on stroke incidence and outcomes. Research directions include developing predictive scoring systems (e.g., combining GCS and modified Fisher scale), evaluating treatment efficacy in different patient subgroups, and exploring diurnal and seasonal patterns in stroke occurrence. The lab integrates clinical neurosurgery with environmental health and neuroprotection to improve patient outcomes.

aneurysmal subarachnoid hemorrhagestroke prognosisneuroprotective agentsenvironmental triggerscerebrovascular disease

Research Overview

Papers
153
Total Citations
1,964
Papers (5y)
31
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
31total
2018
2019
2021
2023
2025
Citations per year (5y)
354total
20182019202120232025

Selected Papers

15
1
Article|123 citations·2008
Role of angiogenic growth factors and inflammatory cytokine on recurrence of chronic subdural hematoma
Hyun-Jong Hong, Young Jin Kim, Hyeong-Joong Yi, Yong Ko, Suck-Jun Oh, Jae Min Kim
Surgical Neurology
NeurologyMedicine
2
Review|60 citations·2018
Intraprocedural Rupture During Endovascular Treatment of Intracranial Aneurysm: Clinical Results and Literature Review
Yung Ki Park, Hyeong-Joong Yi, Kyu-Sun Choi, Young‐Jun Lee, Hyoung-Joon Chun
SJR Q2World Neurosurgery
NeurologyMedicine
3
Article|58 citations·2016
Association between hemorrhagic stroke occurrence and meteorological factors and pollutants
Myung‐Hoon Han, Hyeong-Joong Yi, Yong Ko, Young-Soo Kim, Young‐Jun Lee
SJR Q2BMC NeurologyOA

BACKGROUND: The purpose of this study is to determine whether intracerebral hemorrhage and subarachnoid hemorrhage have different incidence patterns based on monthly variations in meteorological and air pollution parameters in the Seongdong district of Seoul, South Korea. METHODS: From January 1, 2004 to December 31, 2014, 1,477 consecutive hemorrhagic stroke events (>19 years old) were registered among residents of the Seongdong district, Seoul, South Korea. The authors calculated the relative

Health, Toxicology and MutagenesisEnvironmental Science
4
Article|35 citations·2013
Effectiveness of papaverine cisternal irrigation for cerebral vasospasm after aneurysmal subarachnoid hemorrhage and measurement of biomarkers
Jae Hoon Kim, Hyeong-Joong Yi, Yong Ko, Young‐Soo Kim, Dong-Won Kim, Jae Min Kim
SJR Q1Neurological Sciences
NeurologyMedicine
5
Article|33 citations·2018
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model
Kyu-Sun Choi, Han‐Jun Kim, Sun Hee, Se Jin Hwang, Hyeong-Joong Yi
SJR Q2Brain Research Bulletin
SurgeryMedicine
6
Article|33 citations·2013
Therapeutic and prognostic implications of subarachnoid hemorrhage in patients who suffered cardiopulmonary arrest and underwent cardiopulmonary resuscitation during an emergency room stay
Kyu-Sun Choi, Yu Deok Won, Hyeong-Joong Yi, Tae Ho Lim, Young‐Jun Lee, Hyoung-Joon Chun
SJR Q2Clinical Neurology and Neurosurgery
Emergency MedicineMedicine
7
Article|30 citations·2006
Factors Associated with Survival and Neurological Outcome after Cardiopulmonary Resuscitation of Neurosurgical Intensive Care Unit Patients
Hyeong-Joong Yi, Youngsoo Kim, Yong Ko, Suck-Jun Oh, Kwang-Myung Kim, Seong-Hoon Oh
SJR Q1Neurosurgery

Even after initially successful resuscitation, survival and neurological recovery is quite dismal in patients with cerebral lesions. Prognostic factors for neurosurgical patients should be assessed on an individual basis to determine medical futility in the early post-resuscitation period.

Emergency MedicineMedicine
8
Article|29 citations·2014
Incidence and risk factors of postoperative headache after endovascular coil embolization of unruptured intracranial aneurysms
Kyu-Sun Choi, Jung-Hyun Lee, Hyeong-Joong Yi, Hyoung-Joon Chun, Young‐Jun Lee, Dong-Won Kim
SJR Q1Acta Neurochirurgica
NeurologyMedicine
9
Article|27 citations·2018
Predictive Factors of Fever After Aneurysmal Subarachnoid Hemorrhage and Its Impact on Delayed Cerebral Ischemia and Clinical Outcomes
Yung Ki Park, Hyeong-Joong Yi, Kyu-Sun Choi, Young‐Jun Lee, Hyoung-Joon Chun, Sae Min Kwon
SJR Q2World Neurosurgery
NeurologyMedicine
10
Article|25 citations·2018
Predicting factors for shunt-dependent hydrocephalus in patients with aneurysmal subarachnoid hemorrhage
Yung Ki Park, Hyeong-Joong Yi, Kyu-Sun Choi, Young‐Jun Lee, Hyoung-Joon Chun, Sae Min Kwon, Dong-Won Kim
SJR Q1Acta Neurochirurgica
Cellular and Molecular NeuroscienceNeuroscience
11
Article|22 citations·2021
Modified Glasgow coma scale for predicting outcome after subarachnoid hemorrhage surgery
In-Suk Bae, Hyoung-Joon Chun, Kyu-Sun Choi, Hyeong-Joong Yi
SJR Q3MedicineOA

ABSTRACT: There are many grading scales that attempt to predict outcome following aneurysmal subarachnoid hemorrhage (aSAH). Most scales used to assess outcome are based on the neurological status of the patient. Here, we propose a new scale for aSAH patients that combines the Glasgow Coma Scale (GCS) and the modified Fisher scale (mFS).Five hundred ninety-seven patients with aSAH who were treated at our institution between January 2008 and December 2017 were retrospectively analyzed. Initial GC

NeurologyMedicine
12
Review|21 citations·2007
Metastasizing malignant peripheral nerve sheath tumor initially presenting as intracerebral hemorrhage. Case report and review of the literature
Sang Kyu Park, Hyeong-Joong Yi, Seung‐Sam Paik, Young Jin Kim, Yong Ko, Suck-Jun Oh
Surgical Neurology
NeurologyMedicine
13
Article|15 citations·2018
Cerebrolysin for the Treatment of Aneurysmal Subarachnoid Hemorrhage in Adults: A Retrospective Chart Review
Yung Ki Park, Hyeong-Joong Yi, Kyu-Sun Choi, Young‐Jun Lee, Dong‐Won Kim, Sae Min Kwon
SJR Q1Advances in TherapyOA

INTRODUCTION: Cerebrolysin is a neuroprotective drug used in the treatment of acute ischemic stroke. To our knowledge, this drug has never been evaluated in patients with aneurysmal subarachnoid hemorrhage (SAH). The aim of this study was to evaluate the effect of Cerebrolysin in patients with aneurysmal SAH. METHODS: Aneurysmal SAH patients who had their aneurysm obliterated at our institution from 2007 to 2016 were retrospectively studied. Patients received Cerebrolysin treatment or standard c

NeurologyNeuroscience
14
Article|15 citations·2016
Association between Diurnal Variation of Ozone Concentration and Stroke Occurrence: 24-Hour Time Series Study
Myung‐Hoon Han, Hyeong-Joong Yi, Young-Seo Kim, Yong Ko, Youngsoo Kim
SJR Q1PLoS ONEOA

The results show diurnal patterns of ischemic stroke occurrence based on upper and lower median ozone levels for a 24-hour period, which extends understanding of the association between stroke occurrence and environmental influences.

Health, Toxicology and MutagenesisEnvironmental Science
15
Article|14 citations·2012
The relationship between metabolic syndrome (MetS) and spontaneous intracerebral hemorrhage (ICH)
Yung Ki Park, Hyeong-Joong Yi, Young Jun Lee, Hyun Cho, Hyoung-Joon Chun, Suck-Jun Oh
SJR Q1Neurological Sciences
NeurologyMedicine

Research Areas

NeurologySurgeryAerospace EngineeringHealth, Toxicology and MutagenesisCellular and Molecular NeurosciencePathology and Forensic Medicine

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