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Hyung-Seok Seo

Kyung Hee University · Medicine

About the Lab

Professor Hyung-Seok Seo's research lab specializes in perioperative critical care and clinical anesthesiology, focusing on optimizing surgical outcomes through advanced hemodynamic monitoring, airway management, and fluid therapy. The lab investigates physiological challenges in complex surgical settings—such as intracranial surgery, robot-assisted laparoscopy, and liver donation—emphasizing patient safety, hemodynamic stability, and prevention of postoperative complications. Key research directions include the use of dynamic hemodynamic indices (e.g., arterial elastance), prediction of difficult airway, and the role of agents like mannitol in minimizing blood loss and organ injury. The lab integrates clinical decision-making with evidence-based protocols to improve outcomes in high-risk surgical populations.

hemodynamic monitoringairway managementfluid therapypostoperative complicationsrobot-assisted surgery

Research Overview

Papers
80
Total Citations
745
Papers (5y)
26
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
26total
2021
2023
2024
2025
2026
Citations per year (5y)
54total
20212023202420252026

Selected Papers

15
1
Article|39 citations·2016
A prospective randomized trial of the optimal dose of mannitol for intraoperative brain relaxation in patients undergoing craniotomy for supratentorial brain tumor resection
Hyungseok Seo, Eugene Kim, Haesun Jung, Young‐Jin Lim, Jin Wook Kim, Chul‐Kee Park, Young-Bem Se, Young-Tae Jeon, Jung‐Won Hwang, Hee‐Pyoung Park
SJR Q1Journal of neurosurgery

OBJECTIVE Mannitol is used intraoperatively to induce brain relaxation in patients undergoing supratentorial brain tumor resection. The authors sought to determine the dose of mannitol that provides adequate brain relaxation with the fewest adverse effects. METHODS A total of 124 patients were randomized to receive mannitol at 0.25 g/kg (Group A), 0.5 g/kg (Group B), 1.0 g/kg (Group C), and 1.5 g/kg (Group D). The degree of brain relaxation was classified according to a 4-point scale (1, bulging

Developmental NeuroscienceNeuroscience
2
Article|36 citations·2018
Correlation between modified LEMON score and intubation difficulty in adult trauma patients undergoing emergency surgery
Sung-Mi Ji, Eun-Jin Moon, Tae Jun Kim, Jae-Woo Yi, Hyungseok Seo, Bong-Jae Lee
SJR Q1World Journal of Emergency SurgeryOA

Prediction of difficult airway is critical in the airway management of trauma patients . A LEMON method which consists of following assessments; Look-Evaluate-Mallampati-Obstruction-Neck mobility is a fast and easy technique to evaluate patients’ airways in the emergency situation. And a modified LEMON method, which excludes the Mallampati classification from the original LEMON score, also can be used clinically. We investigated the relationship between modified LEMON score and intubation diffic

Anesthesiology and Pain MedicineMedicine
3
Article|32 citations·2015
Dynamic Arterial Elastance in Predicting Arterial Pressure Increase After Fluid Challenge During Robot-Assisted Laparoscopic Prostatectomy
Hyungseok Seo, Yu‐Gyeong Kong, Seok‐Joon Jin, Ji‐Hyun Chin, Hee‐Yeong Kim, Yoon-Kyung Lee, Jai‐Hyun Hwang, Young‐Kug Kim
SJR Q3MedicineOA

During robot-assisted laparoscopic prostatectomy, specific physiological conditions such as carbon dioxide insufflation and the steep Trendelenburg position can alter the cardiac workload and cerebral hemodynamics. Inadequate arterial blood pressure is associated with hypoperfusion, organ damage, and poor outcomes. Dynamic arterial elastance (Ea) has been proposed to be a useful index of fluid management in hypotensive patients. We therefore evaluated whether dynamic Ea can predict a mean arteri

SurgeryMedicine
4
Article|29 citations·2019
Incidence and Risk Factors of Pulmonary Complications after Robot-Assisted Laparoscopic Prostatectomy: A Retrospective Observational Analysis of 2208 Patients at a Large Single Center
Jihion Yu, Jun-Young Park, Doo-Hwan Kim, Sung‐Won Kim, Jai‐Hyun Hwang, Hyungseok Seo, Young‐Kug Kim
SJR Q1Journal of Clinical MedicineOA

Robot-assisted laparoscopic prostatectomy (RALP) is a minimally invasive technique for the treatment of prostate cancer. RALP requires the patient to be placed in the steep Trendelenburg position, along with pneumoperitoneum, which may increase the risk of postoperative pulmonary complications (PPCs). This large single-center retrospective study evaluated the incidence and risk factors of PPCs in 2208 patients who underwent RALP between 2014 and 2017. Patients were divided into those with (PPC g

Pulmonary and Respiratory MedicineMedicine
5
Article|25 citations·2014
An awake double lumen endotracheal tube intubation using the Clarus Video System in a patient with an epiglottic cyst: a case report
Hyungseok Seo, Gunn Lee, Seung-il Ha, Jun‐Gol Song
SJR Q1Korean journal of anesthesiologyOA

A 54-year-old male patient was scheduled for an elective pylorus-preserving pancreaticoduodenectomy combined with video-assisted thoracic surgery at our hospital. This patient had a history of intubation failure in other institutions due to an epiglottic cyst. An airway assessment of the patient was normal. A preoperative laryngoscopy revealed a bulging epiglottic mass covering most of the epiglottis and occupying most of the pharyngeal space. The patient was administered intravenous midazolam 1

Anesthesiology and Pain MedicineMedicine
6
Article|13 citations·2016
High Stroke Volume Variation Method by Mannitol Administration Can Decrease Blood Loss During Donor Hepatectomy
Hyungseok Seo, In‐Gu Jun, Tae‐Yong Ha, Shin Hwang, Sung‐Gyu Lee, Young‐Kug Kim
SJR Q3MedicineOA

Optimal fluid management to reduce blood loss during donor hepatectomy is important for maximizing donor safety. Mannitol can induce osmotic diuresis, helping prevent increased intravascular volume status. We therefore evaluated the effect of high stroke volume variation (SVV) method by mannitol administration and fluid restriction on blood loss during donor hepatectomy.In this prospective study, 64 donors scheduled for donor right hepatectomy were included and allocated into 2 groups. In group

SurgeryMedicine
7
Article|13 citations·2016
A prospective randomised study of a rigid video‐stylet vs. conventional lightwand intubation in cervical spine‐immobilised patients
Hyungseok Seo, Eun Sun Kim, Jongyeon Son, Sang‐Hwan Ji, Seung-Kee Min, Hee‐Pyoung Park
SJR Q1AnaesthesiaOA

, a rigid video-stylet, can provide direct imaging of airway structures, potentially offering improved conditions in cervical spine-immobilised patients. We randomly assigned 168 patients who required cervical immobilisation during tracheal intubation to use of the Optiscope or the lightwand. The initial intubation success rate (95% CI) was 90 (82-95)% with the Optiscope and 87 (78-93)% with the lightwand (p = 0.626). Median (IQR [range]) intubation time was longer (19 (12-41 [5-195] s vs. 15 (8

Anesthesiology and Pain MedicineMedicine
8
Article|10 citations·2016
Intraoperative dexmedetomidine and postoperative cerebral hyperperfusion syndrome in patients who underwent superficial temporal artery-middle cerebral artery anastomosis for moyamoya disease
Hyungseok Seo, Ho Geol Ryu, Je Do Son, Jeong-Soo Kim, Eun Jin Ha, Jeongeun Kim, Hee‐Pyoung Park
SJR Q3MedicineOA

Dexmedetomidine, a selective α2-agonist, reduces cerebral blood flow and has neuroprotective effects against cerebral ischemia/reperfusion injury in experimental animals. We examined whether intraoperative dexmedetomidine would reduce the incidence of postoperative cerebral hyperperfusion syndrome (CHS) after superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis in patients with moyamoya disease.The electronic medical records of 117 moyamoya patients who underwent STA-MCA anas

RheumatologyMedicine
9
Article|9 citations·2013
Similar neuroprotective effects of ischemic and hypoxic preconditioning on hypoxia–ischemia in the neonatal rat: A proton MRS study
Hyungseok Seo, Keun Ho Lim, Jae‐Hyung Choi, Sung‐Moon Jeong
SJR Q3International Journal of Developmental Neuroscience

The aim of this study was to evaluate the effect of ischemic and hypoxic preconditioning on hypoxia-ischemia (HI) in the neonatal rat. Seven-day-old Sprague-Dawley rats were divided into four groups: control, sham, ischemic preconditioning, and hypoxic preconditioning. Ischemic preconditioning with a 10-min occlusion of the right carotid artery and hypoxic preconditioning with 4-h of hypoxia (8% oxygen) were performed 24-h before HI. For HI, all rats underwent right carotid artery ligature, foll

Pediatrics, Perinatology and Child HealthMedicine
10
Article|9 citations·2018
Face-to-face intubation using a lightwand in a patient with severe thoracolumbar kyphosis: a case report
Hyungmo Jeong, Min-Chul Chae, Hyungseok Seo, Jae-Woo Yi, Jong-Man Kang, Bong-Jae Lee
SJR Q1BMC AnesthesiologyOA

BACKGROUND: Severe deformity of the thoracolumbar spine may cause difficulty in airway management during induction of anesthesia. Therefore, special attention must be devoted to patient safety. CASE PRESENTATION: A 65-year-old male with severe thoracolumbar kyphosis was scheduled to undergo posterior spinal fusion under general anesthesia. Due to his inability to lie supine, conventional tracheal intubation under direct laryngoscopy was difficult. Alternatively, face-to-face tracheal intubation

Anesthesiology and Pain MedicineMedicine
11
Article|9 citations·2014
Effect of heated humidified ventilation on bronchial mucus transport velocity in general anaesthesia: A randomized trial
Hyungseok Seo, Sung‐Hoon Kim, Jae-Hyung Choi, Jeong-Yeon Hong, Jai‐Hyun Hwang
SJR Q3Journal of International Medical ResearchOA

OBJECTIVE: To evaluate the effects of heated humidified ventilation on mucociliary function during general anaesthesia. METHODS: Male patients (ASA physical status 1 or 2), scheduled for elective radical retropubic prostatectomy, were allocated to receive sevoflurane general anaesthesia with conventional or heated humidified ventilation. Bronchial mucus transport velocity was assessed via fibreoptic bronchoscope and methylene blue dye at 3h after induction of anaesthesia. RESULTS: Median (SE) br

Anesthesiology and Pain MedicineMedicine
12
Article|7 citations·2015
Effect of Tracheal Cuff Shape on Intracuff Pressure Change During Robot-Assisted Laparoscopic Surgery: The Tapered-Shaped Cuff Tube Versus the Cylindrical-Shaped Cuff Tube
Hyungseok Seo, Ji‐Yeon Bang, Jimi Oh, Woo-Jong Choi, Jun‐Gol Song, Gyu‐Sam Hwang
SJR Q2Journal of Laparoendoscopic & Advanced Surgical Techniques

The TSC tube has a tendency to decrease intracuff pressure change compared with the CSC tube during RALS. However, neither of them was beneficial in preventing intraoperative intracuff pressure increase during RALS.

Anesthesiology and Pain MedicineMedicine
13
Article|6 citations·2020
Lung sonography can improve the specificity of determination of left-sided double-lumen tracheal tube position in both novices and experts: a randomised prospective study
Jun-Young Chung, YoonJu Go, Yong Seok Jang, Bong-Jae Lee, Hyungseok Seo
SJR Q3Journal of International Medical ResearchOA

OBJECTIVE: Lung sonography can be helpful to determine the position of a left-sided double-lumen tube (DLT). However, clinical experience is required for correct assessment. We investigated whether lung sonography can improve the diagnostic efficacy of determining the DLT position in novices and experts. METHODS: In this randomised prospective clinical study, 88 patients were allocated to two groups using auscultation or lung sonography for initial assessment of the DLT position. In each group,

Anesthesiology and Pain MedicineMedicine
14
Review|6 citations·2025
Clinical roles of point-of-care ultrasonography in airway management
Hyungseok Seo, Chung-Sik Oh, Geun Joo Choi, Jung‐Bin Park
SJR Q2Anesthesia and Pain MedicineOA

Point-of-care ultrasonography (POCUS) has emerged as a valuable tool in airway management, providing real-time visualization of airway anatomy with significant advantages in both routine and emergency settings. This review highlights key ultrasonographic techniques, anatomical landmarks, and clinical evidence supporting the growing role of POCUS in modern airway management. It also outlines the clinical applications of POCUS, including prediction of difficult airways and real-time guidance durin

Anesthesiology and Pain MedicineMedicine
15
Article|6 citations·2019
Stroke Volume Variation and Stroke Volume Index Can Predict Fluid Responsiveness after Mini-Volume Challenge Test in Patients Undergoing Laparoscopic Cholecystectomy
Eun-Jin Moon, Seung-Hwan Lee, Jae-Woo Yi, Ju-Hyun Kim, Bong-Jae Lee, Hyungseok Seo
SJR Q2MedicinaOA

Background and Objectives: For using appropriate goal-directed fluid therapy during the surgical conditions of pneumoperitoneum in the reverse Trendelenburg position, we investigated the predictability of various hemodynamic parameters for fluid responsiveness by using a mini-volume challenge test. Materials and Methods: 42 adult patients scheduled for laparoscopic cholecystectomy were enrolled. After general anesthesia was induced, CO2 pneumoperitoneum was applied and the patient was placed in

SurgeryMedicine

Research Areas

Anesthesiology and Pain MedicineSurgeryRheumatologyCritical Care and Intensive Care MedicineNeurologyPulmonary and Respiratory Medicine

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